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International Journal of Nanomedicine Volume 16, 2021 - Issue
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Original Research

Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage

Liu Zi1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;2 Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Wencheng Zhou1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;3 Department of Burn and Plastic Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Jiake Xu1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;4 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Junshu Li5 State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and Collaborative Innovation Center for Biotherapy, Chengdu, Sichuan, People’s Republic of China
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Ning Li2 Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Jianguo Xu1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;4 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;6 West China Brain Research Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Chao You1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;4 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;6 West China Brain Research Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Chengwei Wang1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;2 Department of Integrated Traditional and Western Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of ChinaCorrespondence[email protected] [email protected]
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Meng Tian1 Neurosurgery Research Laboratory, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;4 Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China;6 West China Brain Research Centre, West China Hospital, Sichuan University, Chengdu, Sichuan, People’s Republic of China
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Pages 2933-2947 | Published online: 20 Apr 2021

Citations (11)

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Yating Xu, Anqi Chen, Jiehong Wu, Yan Wan, Mingfeng You, Xinmei Gu, Hongxiu Guo, Sengwei Tan, Quanwei He & Bo Hu. (2022) Nanomedicine: An Emerging Novel Therapeutic Strategy for Hemorrhagic Stroke. International Journal of Nanomedicine 17, pages 1927-1950.
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Articles from other publishers (10)

Ravi Prakash, Akshay Vyawahare, Rahul Sakla, Neha Kumari, Ajay Kumar, Md. Meraj Ansari, Kanika, Chandrashekhar Jori, Arshi Waseem, Abu Junaid Siddiqui, Mohsin Ali Khan, Avril A. B. Robertson, Rehan Khan & Syed Shadab Raza. (2023) NLRP3 Inflammasome-Targeting Nanomicelles for Preventing Ischemia–Reperfusion-Induced Inflammatory Injury. ACS Nano 17:9, pages 8680-8693.
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Xiangyu Zhang, Suliman Khan, Ruixue Wei, Yan Zhang, Yang Liu, Voon Wee Yong & Mengzhou Xue. (2023) Application of nanomaterials in the treatment of intracerebral hemorrhage. Journal of Tissue Engineering 14, pages 204173142311570.
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Oly Katari, Sheetal Yadav, Junia Akhtar & Sanyog Jain. 2023. Nanomedicine-Based Approaches for the Treatment of Dementia. Nanomedicine-Based Approaches for the Treatment of Dementia 169 192 .
Yuting Guo, Weibo Dai, Yan Zheng, Weilin Qiao, Weixuan Chen, Lihua Peng, Hua Zhou, Tingting Zhao, Huimin Liu, Feng Zheng & Peng Sun. (2022) Mechanism and Regulation of Microglia Polarization in Intracerebral Hemorrhage. Molecules 27:20, pages 7080.
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Sabya Sachi Das, Sandeep Kumar Singh, P.R.P. Verma, Rekha Gahtori, Belay Zeleke Sibuh, Kavindra Kumar Kesari, Niraj Kumar Jha, Sugapriya Dhanasekaran, Vijay Kumar Thakur, Ling Shing Wong, Sinouvassane Djearamane & Piyush Kumar Gupta. (2022) Polyester nanomedicines targeting inflammatory signaling pathways for cancer therapy. Biomedicine & Pharmacotherapy 154, pages 113654.
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Eduardo Benarroch. (2022) What Is the Role of Microglial Metabolism in Inflammation and Neurodegeneration?. Neurology 99:3, pages 99-105.
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Muhammed A. Saad, Muhammad Y. Al-Shorbagy & Hany H. Arab. (2022) Targeting the TLR4/NF-κΒ Axis and NLRP1/3 Inflammasomes by Rosuvastatin: A Role in Impeding Ovariectomy-Induced Cognitive Decline Neuropathology in Rats. Molecular Neurobiology 59:7, pages 4562-4577.
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Alanah Sheridan, Caroline P. D. Wheeler-Jones & Matthew C. Gage. (2022) The Immunomodulatory Effects of Statins on Macrophages. Immuno 2:2, pages 317-343.
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Yoichi Morofuji, Shinsuke Nakagawa, Kenta Ujifuku, Takashi Fujimoto, Kaishi Otsuka, Masami Niwa & Keisuke Tsutsumi. (2022) Beyond Lipid-Lowering: Effects of Statins on Cardiovascular and Cerebrovascular Diseases and Cancer. Pharmaceuticals 15:2, pages 151.
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George E. Barreto, Janneth Gonzalez, Željko Reiner, Tannaz Jamialahmadi, Valentina Echeverria, Ghulam Md Ashraf & Amirhossein Sahebkar. (2021) In silico interactions of statins with cell death-inducing DNA fragmentation factor-like effector A (CIDEA). Chemico-Biological Interactions 345, pages 109528.
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