275
Views
76
CrossRef citations to date
0
Altmetric
Review

Neurological disorders and therapeutics targeted to surmount the blood–brain barrier

, &
Pages 3259-3278 | Published online: 09 Jul 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Mahendra Rai, Avinash P. Ingle, Swapnil Gaikwad, Felipe Hering Padovani & Monica Alves. (2016) The role of nanotechnology in control of human diseases: perspectives in ocular surface diseases. Critical Reviews in Biotechnology 36:5, pages 777-787.
Read now
Agnieszka Jurecka & Anna Tylki-Szymańska. (2015) Enzyme replacement therapy: lessons learned and emerging questions. Expert Opinion on Orphan Drugs 3:3, pages 293-305.
Read now
Cui-Tao Lu, Ying-Zheng Zhao, Ho Lun Wong, Jun Cai, Lei Peng & Xin-Qiao Tian. (2014) Current approaches to enhance CNS delivery of drugs across the brain barriers. International Journal of Nanomedicine 9, pages 2241-2257.
Read now
Bhasker Sriramoju, Rupinder K Kanwar & Jagat R Kanwar. (2014) Nanoformulated cell-penetrating survivin mutant and its dual actions. International Journal of Nanomedicine 9, pages 3279-3298.
Read now

Articles from other publishers (72)

Ruth Naomi, Muhammad Dain Yazid, Soo Huat Teoh, Santhra Segaran Balan, Halim Shariff, Jaya Kumar, Hasnah Bahari & Hashim Embong. (2023) Dietary Polyphenols as a Protection against Cognitive Decline: Evidence from Animal Experiments; Mechanisms and Limitations. Antioxidants 12:5, pages 1054.
Crossref
Satar Yousefiasl & Esmaeel Sharifi. 2023. Stimuli-Responsive Materials for Biomedical Applications. Stimuli-Responsive Materials for Biomedical Applications 181 201 .
Shalini Mani, Divya Jindal & Manisha Singh. (2023) Gene Therapy, A Potential Therapeutic Tool for Neurological and Neuropsychiatric Disorders: Applications, Challenges and Future Perspective. Current Gene Therapy 23:1, pages 20-40.
Crossref
Jing Zhou, Chao Fang, Chao Rong, Tao Luo, Junjie Liu & Kun Zhang. (2023) Reactive oxygen species-sensitive materials: A promising strategy for regulating inflammation and favoring tissue regeneration. Smart Materials in Medicine 4, pages 427-446.
Crossref
Naumih M. Noah, Betty N. Mbatia & Calvin A. Omolo. 2023. Advanced Nanoformulations. Advanced Nanoformulations 685 717 .
Roshani R. Pagar & Meghraj V. Suryawanshi. (2022) A SYSTEMATIC OVERVIEW ON NOSE TO BRAIN DRUG DELIVERY SYSTEM IN TREATMENT OF NEURODEGENERATIVE DISORDERS. Indian Drugs 59:11, pages 7-14.
Crossref
Richa Tyagi, Bhupesh Vaidya & Shyam Sunder Sharma. (2022) Crosstalk between neurological, cardiovascular, and lifestyle disorders: insulin and lipoproteins in the lead role. Pharmacological Reports 74:5, pages 790-817.
Crossref
Taís C. Ribeiro, Rafael M. Sábio, Gabriela C. Carvalho, Bruno Fonseca-Santos & Marlus Chorilli. (2022) Exploiting mesoporous silica, silver and gold nanoparticles for neurodegenerative diseases treatment. International Journal of Pharmaceutics 624, pages 121978.
Crossref
Jaskiran Kaur, Monica Gulati, Bhupinder Kapoor, Niraj Kumar Jha, Piyush Kumar Gupta, Gaurav Gupta, Dinesh Kumar Chellappan, Hari Prasad Devkota, Parteek Prasher, Md Salahuddin Ansari, Faris F. Aba Alkhayl, Mohammed F. Arshad, Andrew Morris, Yahya E. Choonara, Jon Adams, Kamal Dua & Sachin Kumar Singh. (2022) Advances in designing of polymeric micelles for biomedical application in brain related diseases. Chemico-Biological Interactions 361, pages 109960.
Crossref
Vanshul Saini, Ajit Singh, Rahul Shukla, Keerti Jain & A. K. Yadav. (2022) Silymarin-Encapsulated Xanthan Gum–Stabilized Selenium Nanocarriers for Enhanced Activity Against Amyloid Fibril Cytotoxicity. AAPS PharmSciTech 23:5.
Crossref
Adriana Trapani, Stefania Cometa, Elvira De Giglio, Filomena Corbo, Roberta Cassano, Maria Luisa Di Gioia, Sonia Trombino, Md Niamat Hossain, Sante Di Gioia, Giuseppe Trapani & Massimo Conese. (2022) Novel Nanoparticles Based on N,O-Carboxymethyl Chitosan-Dopamine Amide Conjugate for Nose-to-Brain Delivery. Pharmaceutics 14:1, pages 147.
Crossref
Manpreet Kaur, Rupinder Kaur Sodhi, Vaskuri G.S. Sainaga Jyothi, Veerabomma Haritha Sree, Shubhra, Pankaj Kumar Singh, Neelesh Kumar Mehra, Dharmendra Kumar Khatri, Saurabh Srivastava, Shashi Bala Singh, Jitender Madan & Satish Sardana. 2022. Multifunctional Nanocarriers. Multifunctional Nanocarriers 289 345 .
Dania Alphonse Jose, Krishnapriya & P. S. Baby Chakrapani. 2022. Micro- and Nano-containers for Smart Applications. Micro- and Nano-containers for Smart Applications 309 325 .
Aaishwarya Deshmukh, Jayvadan Patel, Govind Vyas & Mukesh Patel. 2022. Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems. Pharmacokinetics and Pharmacodynamics of Nanoparticulate Drug Delivery Systems 365 384 .
Mahtab Amiri, Samira Jafari, Masoumeh Kurd, Hamed Mohamadpour, Maryam Khayati, Farbod Ghobadinezhad, Omid Tavallaei, Hossein Derakhshankhah, Soroor Sadegh Malvajerd & Zhila Izadi. (2021) Engineered Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as New Generations of Blood–Brain Barrier Transmitters. ACS Chemical Neuroscience 12:24, pages 4475-4490.
Crossref
Claudia Riccardi, Filomena Napolitano, Daniela Montesarchio, Simone Sampaolo & Mariarosa Anna Beatrice Melone. (2021) Nanoparticle-Guided Brain Drug Delivery: Expanding the Therapeutic Approach to Neurodegenerative Diseases. Pharmaceutics 13:11, pages 1897.
Crossref
Johra Khan, Mithun Rudrapal, Eijaz Ahmed Bhat, Ahmad Ali, Mohammad Alaidarous, Bader Alshehri, Saeed Banwas, Randa Ismail & Chukwuebuka Egbuna. (2021) Perspective Insights to Bio-Nanomaterials for the Treatment of Neurological Disorders. Frontiers in Bioengineering and Biotechnology 9.
Crossref
Mark J. Lynch & Oliviero L. Gobbo. (2021) Advances in Non-Animal Testing Approaches towards Accelerated Clinical Translation of Novel Nanotheranostic Therapeutics for Central Nervous System Disorders. Nanomaterials 11:10, pages 2632.
Crossref
Viridiane Gratpain, Ariane Mwema, Yasmine Labrak, Giulio G. Muccioli, Vincent van Pesch & Anne des Rieux. (2021) Extracellular vesicles for the treatment of central nervous system diseases. Advanced Drug Delivery Reviews 174, pages 535-552.
Crossref
Roberta Cassano, Camilla Servidio & Sonia Trombino. (2021) Biomaterials for Drugs Nose–Brain Transport: A New Therapeutic Approach for Neurological Diseases. Materials 14:7, pages 1802.
Crossref
Xun Zhang, Jie Zhou, Zhongwei Gu, Hu Zhang, Qiyong Gong & Kui Luo. (2021) Advances in nanomedicines for diagnosis of central nervous system disorders. Biomaterials 269, pages 120492.
Crossref
Hitendra S. Mahajan & Payal H. Patil. 2021. Direct Nose-to-Brain Drug Delivery. Direct Nose-to-Brain Drug Delivery 225 245 .
Ikram Ahmad, Hina Tabassum, Farwa Batool Shamsi, Saad Maroof Saeed, Awais Ahmad & Shahid Hussain. 2021. Nanomedicine Manufacturing and Applications. Nanomedicine Manufacturing and Applications 173 191 .
Nabodita Sinha, Abhayraj Shrikrishna Joshi & Ashwani Kumar Thakur. (2020) Analytical validation of an ATR-FTIR based method for quantifying the amount of polysorbate 80 adsorbed on PLGA nanoparticles. Analytical Methods 12:44, pages 5360-5366.
Crossref
Mukta Agrawal, Shailendra Saraf, Swarnlata Saraf, Sunil K. Dubey, Anu Puri, Umesh Gupta, Prashant Kesharwani, V. Ravichandiran, Pramod Kumar, V.G.M. Naidu, Upadhyayula Suryanarayana Murty, Ajazuddin & Amit Alexander. (2020) Stimuli-responsive In situ gelling system for nose-to-brain drug delivery. Journal of Controlled Release 327, pages 235-265.
Crossref
Tao Ming Sim, Dinesh Tarini, S. Thameem Dheen, Boon Huat Bay & Dinesh Kumar Srinivasan. (2020) Nanoparticle-Based Technology Approaches to the Management of Neurological Disorders. International Journal of Molecular Sciences 21:17, pages 6070.
Crossref
G.Y. Wang, S.L. Rayner, R. Chung, B.Y. Shi & X.J. Liang. (2020) Advances in nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis. Materials Today Bio 6, pages 100055.
Crossref
Yao Liu, Wei Liu, Sha Xiong, Jingshan Luo, Ye Li, Yuying Zhao, Qun Wang, Zexin Zhang, Xiaojia Chen & Tongkai Chen. (2020) Highly stabilized nanocrystals delivering Ginkgolide B in protecting against the Parkinson’s disease. International Journal of Pharmaceutics 577, pages 119053.
Crossref
Nina Filipczak, Jiayi Pan, Satya Siva Kishan Yalamarty & Vladimir P. Torchilin. (2020) Recent advancements in liposome technology. Advanced Drug Delivery Reviews 156, pages 4-22.
Crossref
Sandeep Ramchandra Pai, Varsha Vasantrao Sonkamble & Nilesh Shirish Wagh. 2020. Plant-derived Bioactives. Plant-derived Bioactives 409 433 .
William C. Ballance, Ellen C. Qin, Hee Jung Chung, Martha U. Gillette & Hyunjoon Kong. (2019) Reactive oxygen species-responsive drug delivery systems for the treatment of neurodegenerative diseases. Biomaterials 217, pages 119292.
Crossref
B.A. Aderibigbe, T. Naki & S.J. Owonubi. 2019. Handbook of Graphene. Handbook of Graphene 225 246 .
Zheng Zhang, Jingrong Yang, Qingqing Min, Chenjie Ling, Debabrata Maiti, Jiaying Xu, Liqiang Qin & Kai Yang. (2019) Holo-Lactoferrin Modified Liposome for Relieving Tumor Hypoxia and Enhancing Radiochemotherapy of Cancer. Small 15:6, pages 1803703.
Crossref
John M. McGregor, Nancy D. Doolittle, Emily Youngers, Susan D. Bell & Edward A. Neuwelt. 2019. Nervous System Drug Delivery. Nervous System Drug Delivery 57 72 .
Shabir Ahmad GanaiShabir Ahmad Ganai. 2019. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders. Histone Deacetylase Inhibitors — Epidrugs for Neurological Disorders 11 19 .
Anisha A. D’Souza. 2019. Nanotechnology: Applications in Energy, Drug and Food. Nanotechnology: Applications in Energy, Drug and Food 209 225 .
Sathika G. G. Arachchige, Ryan Rienzie & Nadeesh M. Adassooriya. 2019. Nanobiotechnology in Neurodegenerative Diseases. Nanobiotechnology in Neurodegenerative Diseases 267 287 .
Khwaja Salahuddin Siddiqi, Azamal Husen, Sayed Sartaj Sohrab & Mensur Osman Yassin. (2018) Recent Status of Nanomaterial Fabrication and Their Potential Applications in Neurological Disease Management. Nanoscale Research Letters 13:1.
Crossref
Amit Sharma, Min-Goo Lee, Hu Shi, Miae Won, Jonathan F. Arambula, Jonathan L. Sessler, Jin Yong Lee, Sung-Gil Chi & Jong Seung Kim. (2018) Overcoming Drug Resistance by Targeting Cancer Bioenergetics with an Activatable Prodrug. Chem 4:10, pages 2370-2383.
Crossref
B.I. Tamba, V. Streinu, G. Foltea, A.N. Neagu, G. Dodi, M. Zlei, A. Tijani & C. Stefanescu. (2018) Tailored surface silica nanoparticles for blood-brain barrier penetration: Preparation and in vivo investigation. Arabian Journal of Chemistry 11:6, pages 981-990.
Crossref
Peramaiyan Rajendran, Ya‐Fang Chen, Yu‐Feng Chen, Li‐Chin Chung, Shanmugam Tamilselvi, Chia‐Yao Shen, Cecilia Hsuan Day, Ray‐Jade Chen, Vijaya P. Viswanadha, Wei‐Wen Kuo & Chih‐Yang Huang. (2018) The multifaceted link between inflammation and human diseases. Journal of Cellular Physiology 233:9, pages 6458-6471.
Crossref
Natalia Fernández-Bertólez, Carla Costa, Fátima Brandão, Gözde Kiliç, José Alberto Duarte, Joao Paulo Teixeira, Eduardo Pásaro, Vanessa Valdiglesias & Blanca Laffon. (2018) Toxicological assessment of silica-coated iron oxide nanoparticles in human astrocytes. Food and Chemical Toxicology 118, pages 13-23.
Crossref
Blessing Aderibigbe. (2018) In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases. Pharmaceutics 10:2, pages 40.
Crossref
Sau Har Lee, Nadia Atiya, Seok Mui Wang, Rishya Manikam, Chandramathi Samudi Raju & Shamala Devi Sekaran. (2018) Loss of Transfected Human Brain Micro-Vascular Endothelial Cell Integrity during Herpes Simplex Virus Infection. Intervirology 61:4, pages 193-203.
Crossref
N. Poovaiah, Z. Davoudi, H. Peng, B. Schlichtmann, S. Mallapragada, B. Narasimhan & Q. Wang. (2018) Treatment of neurodegenerative disorders through the blood–brain barrier using nanocarriers. Nanoscale 10:36, pages 16962-16983.
Crossref
Sophia Antimisiaris, Spyridon Mourtas & Konstantina Papadia. 2018. Design of Nanostructures for Versatile Therapeutic Applications. Design of Nanostructures for Versatile Therapeutic Applications 255 324 .
Arunachalam Muthuraman. 2018. Nanostructures for the Engineering of Cells, Tissues and Organs. Nanostructures for the Engineering of Cells, Tissues and Organs 105 154 .
Mohammed Nadim Sardoiwala, Babita Kaundal & Subhasree Roy Choudhury. 2018. Handbook of Nanomaterials for Industrial Applications. Handbook of Nanomaterials for Industrial Applications 696 709 .
Jiaming Liu, Fangyan Wang, Suzhi Liu, Jimei Du, Xuezhen Hu, Jiaojiao Xiong, Renchi Fang, Wenqian Chen & Jing Sun. (2017) Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1. Journal of the Neurological Sciences 381, pages 176-181.
Crossref
Mukta Agrawal, Ajazuddin, Dulal K. Tripathi, Swarnlata Saraf, Shailendra Saraf, Sophia G. Antimisiaris, Spyridon Mourtas, Margareta Hammarlund-Udenaes & Amit Alexander. (2017) Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease. Journal of Controlled Release 260, pages 61-77.
Crossref
Anil Kumar Kalvala, Priyanka Giri, Jyothirmai Kaligatla, Wahid Khan & Ashutosh Kumar. 2017. Advances in Personalized Nanotherapeutics. Advances in Personalized Nanotherapeutics 157 185 .
Jing Sun, Fangyan Wang, Guangliang Hong, Mengqi Pang, Hailing Xu, Haixiao Li, Feng Tian, Renchi Fang, Ye Yao & Jiaming Liu. (2016) Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. Neuroscience Letters 618, pages 159-166.
Crossref
Kathrin Backes, Helga Lorenz, Loic Laplanche, Thomas J. Hudzik, Heidrun Potschka & Katja Hempel. (2016) A retrospective evaluation of species-specific sensitivity for neurological signs in toxicological studies: Is the dog more sensitive than the non-human primate?. Toxicology Letters 243, pages 78-87.
Crossref
H. G. StratmannH. G. Stratmann. 2016. Using Medicine in Science Fiction. Using Medicine in Science Fiction 361 388 .
Deqing Sun, Aiying Xue, Bin Zhang, Haiyan Lou, Huanying Shi & Xiumei Zhang. (2015) Polysorbate 80-coated PLGA nanoparticles improve the permeability of acetylpuerarin and enhance its brain-protective effects in rats. Journal of Pharmacy and Pharmacology 67:12, pages 1650-1662.
Crossref
Bhasker Sriramoju, Prasad Neerati, Rupinder K. Kanwar & Jagat R. Kanwar. (2015) Brain targeted PLGA nanocarriers alleviating amyloid-Β expression and preserving basal survivin in degenerating mice model. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1852:11, pages 2423-2431.
Crossref
Shibu M. Poulose, Nopporn Thangthaeng, Marshall G. Miller & Barbara Shukitt-Hale. (2015) Effects of pterostilbene and resveratrol on brain and behavior. Neurochemistry International 89, pages 227-233.
Crossref
Arsalan Ahmed, Chao Zhang, Jian Guo, Yong Hu & Xiqun Jiang. (2015) Fabrication and Characterization of Gd-DTPA-Loaded Chitosan-Poly(Acrylic Acid) Nanoparticles for Magnetic Resonance Imaging. Macromolecular Bioscience 15:8, pages 1105-1114.
Crossref
K. K. Pulicherla & Mahendra Kumar Verma. (2015) Targeting Therapeutics Across the Blood Brain Barrier (BBB), Prerequisite Towards Thrombolytic Therapy for Cerebrovascular Disorders—an Overview and Advancements. AAPS PharmSciTech 16:2, pages 223-233.
Crossref
Surya K. Mallapragada, Timothy M. Brenza, JoEllyn M. McMillan, Balaji Narasimhan, Donald S. Sakaguchi, Anup D. Sharma, Svitlana Zbarska & Howard E. Gendelman. (2015) Enabling nanomaterial, nanofabrication and cellular technologies for nanoneuromedicines. Nanomedicine: Nanotechnology, Biology and Medicine 11:3, pages 715-729.
Crossref
Laura Bana, Stefania Minniti, Elisa Salvati, Silvia Sesana, Vanessa Zambelli, Alfredo Cagnotto, Antonina Orlando, Emanuela Cazzaniga, Rob Zwart, Wiep Scheper, Massimo Masserini & Francesca Re. (2014) Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood–brain-barrier: Implications for therapy of Alzheimer disease. Nanomedicine: Nanotechnology, Biology and Medicine 10:7, pages 1583-1590.
Crossref
Ravi Kant Upadhyay. (2014) Transendothelial Transport and Its Role in Therapeutics. International Scholarly Research Notices 2014, pages 1-39.
Crossref
Clara Grosso, Patrícia Valentão, Federico Ferreres & Paula Andrade. (2014) Bioactive Marine Drugs and Marine Biomaterials for Brain Diseases. Marine Drugs 12:5, pages 2539-2589.
Crossref
Weirong Fang, Rui Zhang, Lan Sha, Peng Lv, Erxin Shang, Dan Han, Jie Wei, Xiaohan Geng, Qichuan Yang & Yunman Li. (2014) Platelet activating factor induces transient blood-brain barrier opening to facilitate edaravone penetration into the brain. Journal of Neurochemistry 128:5, pages 662-671.
Crossref
Howard E GendelmanR Lee Mosley, Michael D Boska & JoEllyn McMillan. (2014) The promise of nanoneuromedicine. Nanomedicine 9:2, pages 171-176.
Crossref
Ravi Kant Upadhyay. (2014) Drug Delivery Systems, CNS Protection, and the Blood Brain Barrier. BioMed Research International 2014, pages 1-37.
Crossref
Antonietta Vilella, Giovanni Tosi, Andreas M. Grabrucker, Barbara Ruozi, Daniela Belletti, Maria Angela Vandelli, Tobias M. Boeckers, Flavio Forni & Michele Zoli. (2014) Insight on the fate of CNS-targeted nanoparticles. Part I: Rab5-dependent cell-specific uptake and distribution. Journal of Controlled Release 174, pages 195-201.
Crossref
Narenda Kumar & Rajiv Kumar. 2014. Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases. Nanotechnology and Nanomaterials in the Treatment of Life-threatening Diseases 109 175 .
Yuan Yin, Dina Rassias & Anjana Jain. 2014. Natural and Synthetic Biomedical Polymers. Natural and Synthetic Biomedical Polymers 373 386 .
JoEllyn M. McMillan, Xin-Ming Liu & Howard E. Gendelman. 2014. Current Laboratory Methods in Neuroscience Research. Current Laboratory Methods in Neuroscience Research 223 231 .
Dongwei Guo, JoEllyn M. McMillan & Howard E. Gendelman. 2014. Handbook of Neurotoxicity. Handbook of Neurotoxicity 2125 2156 .
Jens Pahnke, Christina Fröhlich, Markus Krohn, Toni Schumacher & Kristin Paarmann. (2013) Impaired mitochondrial energy production and ABC transporter function—A crucial interconnection in dementing proteopathies of the brain. Mechanisms of Ageing and Development 134:10, pages 506-515.
Crossref