121
Views
62
CrossRef citations to date
0
Altmetric
Original Research

Core-shell hybrid liposomal vesicles loaded with panax notoginsenoside: preparation, characterization and protective effects on global cerebral ischemia/reperfusion injury and acute myocardial ischemia in rats

, , , , , , & show all
Pages 4299-4310 | Published online: 06 Aug 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (12)

Sajad Fakhri, Sadaf Abdian, Seyede Nazanin Zarneshan, Seyed Zachariah Moradi, Mohammad Hosein Farzaei & Mohammad Abdollahi. (2022) Nanoparticles in Combating Neuronal Dysregulated Signaling Pathways: Recent Approaches to the Nanoformulations of Phytochemicals and Synthetic Drugs Against Neurodegenerative Diseases. International Journal of Nanomedicine 17, pages 299-331.
Read now
Mahvash Hesari, Pantea Mohammadi, Fatemeh Khademi, Dareuosh Shackebaei, Saeideh Momtaz, Narges Moasefi, Mohammad Hosein Farzaei & Mohammad Abdollahi. (2021) Current Advances in the Use of Nanophytomedicine Therapies for Human Cardiovascular Diseases. International Journal of Nanomedicine 16, pages 3293-3315.
Read now
Andrea Perrelli, Parisa Fatehbasharzad, Valerio Benedetti, Chiara Ferraris, Marco Fontanella, Elisa De Luca, Mauro Moglianetti, Luigi Battaglia & Saverio Francesco Retta. (2021) Towards precision nanomedicine for cerebrovascular diseases with emphasis on Cerebral Cavernous Malformation (CCM). Expert Opinion on Drug Delivery 18:7, pages 849-876.
Read now
Hai Liu, Jianqiong Yang, Wanqing Yang, Shaonan Hu, Yali Wu, Bo Zhao, Haiyan Hu & Shouying Du. (2020) Focus on Notoginsenoside R1 in Metabolism and Prevention Against Human Diseases. Drug Design, Development and Therapy 14, pages 551-565.
Read now
Syed Abdullah Alkaff, Krishna Radhakrishnan, Anu Maashaa Nedumaran, Ping Liao & Bertrand Czarny. (2020) Nanocarriers for Stroke Therapy: Advances and Obstacles in Translating Animal Studies. International Journal of Nanomedicine 15, pages 445-464.
Read now
Heshu Sulaiman Rahman, Hemn Hassan Othman, Nahidah Ibrahim Hammadi, Swee Keong Yeap, Kawa Mohammad Amin, Nozlena Abdul Samad & Noorjahan Banu Alitheen. (2020) Novel Drug Delivery Systems for Loading of Natural Plant Extracts and Their Biomedical Applications. International Journal of Nanomedicine 15, pages 2439-2483.
Read now
Mengshuang Li, Jie Lan, Xuefei Li, Meng Xin, Hui Wang, Fan Zhang, Xiaohong Lu, Zengfang Zhuang & Xianggen Wu. (2019) Novel ultra-small micelles based on ginsenoside Rb1: a potential nanoplatform for ocular drug delivery. Drug Delivery 26:1, pages 481-489.
Read now
Carmelo Puglia, Maria Rosaria Lauro, Giorgia Giusy Tirendi, Giuseppina Emanuela Fassari, Claudia Carbone, Francesco Bonina & Giovanni Puglisi. (2017) Modern drug delivery strategies applied to natural active compounds. Expert Opinion on Drug Delivery 14:6, pages 755-768.
Read now
Jing Zhang, Yingchong Chen, Xiang Li, Xinli Liang & Xiaojian Luo. (2016) The influence of different long-circulating materials on the pharmacokinetics of liposomal vincristine sulfate. International Journal of Nanomedicine 11, pages 4187-4197.
Read now
Palanivel Ganesan, Hyun-Myung Ko, In-Su Kim & Dong-Kug Choi. (2015) Recent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinson’s disease models. International Journal of Nanomedicine 10, pages 6757-6772.
Read now

Articles from other publishers (50)

Sri Renukadevi Balusamy, Haribalan Perumalsamy, Md. Amdadul Huq, Tae Hyun Yoon, Ivan Mijakovic, Lakshmi Thangavelu, Deok Chun Yang & Shadi Rahimi. (2023) A comprehensive and systemic review of ginseng‐based nanomaterials: Synthesis, targeted delivery, and biomedical applications. Medicinal Research Reviews 43:5, pages 1374-1410.
Crossref
Lili Niu, Xiangyu Qin, Litao Wang, Na Guo, Hongyan Cao, Hanghang Li, Chunjian Zhao, Huimei Wang & Yujie Fu. (2022) Upgrading the accumulation of ginsenoside Rd in Panax notoginseng by a novel glycosidase-producing endophytic fungus G11-7. Folia Microbiologica 68:3, pages 441-452.
Crossref
Yaru Wang, Yunxia Shang, Fengyu Tang, Kun Qiu, Xiaohui Wei & Zhengtao Wang. (2023) Self-Double-Emulsifying Drug Delivery System Enteric-Coated Capsules: A Novel Approach to Improve Oral Bioavailability and Anti-inflammatory Activity of Panax notoginseng Saponins. AAPS PharmSciTech 24:4.
Crossref
Mithun Singh Rajput, Nilesh Prakash Nirmal, Viral Patel, Purnima Dey Sarkar & Manan Raval. 2023. Recent Frontiers of Phytochemicals. Recent Frontiers of Phytochemicals 463 482 .
Chen-Te Jen, Bo-Yang Hsu & Bing-Huei Chen. (2022) A study on anti-fatigue effects in rats by nanoemulsion and liposome prepared from American ginseng root residue extract. Food Bioscience 50, pages 102130.
Crossref
Fahadul Islam, Md Mohaimenul Islam, Atkia Farzana Khan Meem, Mohamed H. Nafady, Md Rezaul Islam, Aklima Akter, Saikat Mitra, Fahad A. Alhumaydhi, Talha Bin Emran, Ameer Khusro, Jesus Simal-Gandara, Aziz Eftekhari, Fatemeh Karimi & Mehdi Baghayeri. (2022) Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases. Chemosphere 307, pages 136020.
Crossref
Sonal Upadhyay, Ravi Bhushan & Mithun Rudrapal. 2022. Phytoantioxidants and Nanotherapeutics. Phytoantioxidants and Nanotherapeutics 173 201 .
Han Li, Jing Zhu, Yan-wu Xu, Fang-fang Mou, Xiao-li Shan, Qiang-li Wang, Bao-nian Liu, Ke Ning, Jia-jia Liu, Ya-chao Wang, Jin-xia Mi, Xiaohui Wei, Shui-jin Shao, Guo-hong Cui, Rong Lu & Hai-dong Guo. (2022) Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial infarction. Redox Biology 54, pages 102384.
Crossref
Zhongzhong Li, Cheng Jiang, Luxiao Chai, Taojian Fan, Chaozhou Li, Zhi Chen, Weichun Huang, Bin Zhang, Omar A. Al-Hartomy, Ahmed Al-Ghamdi, Swelm Wageh, Abdullah G. Al-Sehemi, Lin Kang, Quan Liu, Xiaoyun Liu, Qingshan Geng, Zhongjian Xie & Han Zhang. (2022) New insights to atherosclerosis management: Role of nanomaterials. Applied Materials Today 27, pages 101466.
Crossref
Daohe Wei, Han Yang, Yue Zhang, Xinhui Zhang, Jian Wang, Xiaoli Wu & Jin Chang. (2022) Nano-traditional Chinese medicine: a promising strategy and its recent advances. Journal of Materials Chemistry B 10:16, pages 2973-2994.
Crossref
Seyede Nazanin Zarneshan, Sajad Fakhri & Haroon Khan. (2022) Targeting Akt/CREB/BDNF signaling pathway by ginsenosides in neurodegenerative diseases: A mechanistic approach. Pharmacological Research 177, pages 106099.
Crossref
Chhavi Bhalothia & Girima Nagda. (2022) Nanotherapeutics a promising approach for treatment of Parkinson’s disease. Materials Today: Proceedings 69, pages A1-A13.
Crossref
Yotsanan Weerapol & Pornsak Sriamornsak. 2022. Herbal Bioactive-Based Drug Delivery Systems. Herbal Bioactive-Based Drug Delivery Systems 409 418 .
Namrata Sangwan & Pramod K. Avti. 2022. Regenerative Therapies in Ischemic Stroke Recovery. Regenerative Therapies in Ischemic Stroke Recovery 157 197 .
Jyotsna Shankar, Geetha K.M & Barnabas Wilson. (2021) Potential applications of nanomedicine for treating Parkinson's disease. Journal of Drug Delivery Science and Technology 66, pages 102793.
Crossref
Jing Zhang, Kaili Hu, Liuqing Di, Penglong Wang, Zhidong Liu, Jinming Zhang, Pengfei Yue, Wantong Song, Jingwei Zhang, Tongkai Chen, Zuhua Wang, Yongtai Zhang, Xiaoying Wang, Changyou Zhan, Yung-Chi Cheng, Xiang Li, Quan Li, Jing-Yu Fan, Youqing Shen, Jing-Yan Han & Hongzhi Qiao. (2021) Traditional herbal medicine and nanomedicine: Converging disciplines to improve therapeutic efficacy and human health. Advanced Drug Delivery Reviews 178, pages 113964.
Crossref
Jinyan Wan, Yu Long, Songyu Liu, Yulu Zhang, Yan Xiang, Dan Li, Ai Shi, Yu Shuang, Ying Li, Yanan He, Nan Li & Yongmei Guan. (2021) Geniposide-Loaded Liposomes for Brain Targeting: Development, Evaluation, and In Vivo Studies. AAPS PharmSciTech 22:7.
Crossref
Anastasia Kyriakoudi, Eleni Spanidi, Ioannis Mourtzinos & Konstantinos Gardikis. (2021) Innovative Delivery Systems Loaded with Plant Bioactive Ingredients: Formulation Approaches and Applications. Plants 10:6, pages 1238.
Crossref
Guini Song, Min Zhao, Hanmin Chen, Cameron Lenahan, Xiangyue Zhou, Yibo Ou & Yue He. (2021) The Role of Nanomaterials in Stroke Treatment: Targeting Oxidative Stress. Oxidative Medicine and Cellular Longevity 2021, pages 1-15.
Crossref
Andleeb Khan, Sadaf Jahan, Saeed Alshahrani, Bader Mohammed Alshehri, Aga Syed Sameer, Azher Arafah, Ajaz Ahmad & Muneeb U. Rehman. 2021. Phytomedicine. Phytomedicine 581 620 .
Bang-Yue Luo, Jia-Li Jiang, Yi-Fan Fang, Fang Yang, Meng-Die Yin, Bing-Chen Zhang, Rui-Rui Zhao & Jing-Wei Shao. (2020) The effects of ginsenosides on platelet aggregation and vascular intima in the treatment of cardiovascular diseases: From molecular mechanisms to clinical applications. Pharmacological Research 159, pages 105031.
Crossref
Firoozeh Alavian & Nasrin Shams. (2020) Oral and Intra-nasal Administration of Nanoparticles in the Cerebral Ischemia Treatment in Animal Experiments: Considering its Advantages and Disadvantages. Current Clinical Pharmacology 15:1, pages 20-29.
Crossref
Fereshteh Bayat, Reza Hosseinpour-Moghadam, Fatemeh Mehryab, Yousef Fatahi, Niayesh Shakeri, Rassoul Dinarvand, Timo L.M. Ten Hagen & Azadeh Haeri. (2020) Potential application of liposomal nanodevices for non-cancer diseases: an update on design, characterization and biopharmaceutical evaluation. Advances in Colloid and Interface Science 277, pages 102121.
Crossref
Mohammad Zaidur Rahman Sabuj & Nazrul Islam. 2020. Nanophytomedicine. Nanophytomedicine 55 70 .
Anna Rita Bilia, Vieri Piazzini & Maria Camilla Bergonzi. 2020. Sustainable Agriculture Reviews 44. Sustainable Agriculture Reviews 44 1 46 .
Priyanka Kumari, Suaib Luqman & Abha Meena. (2019) Application of the combinatorial approaches of medicinal  and aromatic plants with nanotechnology and its impacts on healthcare. DARU Journal of Pharmaceutical Sciences 27:1, pages 475-489.
Crossref
Weijie Xie, Ping Zhou, Yifan Sun, Xiangbao Meng, Ziru Dai, Guibo Sun & Xiaobo Sun. (2018) Protective Effects and Target Network Analysis of Ginsenoside Rg1 in Cerebral Ischemia and Reperfusion Injury: A Comprehensive Overview of Experimental Studies. Cells 7:12, pages 270.
Crossref
Anna Rita Bilia, Vieri Piazzini, Martina Asprea, Laura Risaliti, Giulia Vanti & Maria Camilla Bergonzi. (2018) Plants Extracts Loaded in Nanocarriers: An Emergent Formulating Approach. Natural Product Communications 13:9, pages 1934578X1801300.
Crossref
Xiaohong Tracey GanMorris Karmazyn. (2018) Cardioprotection by ginseng: experimental and clinical evidence and underlying mechanisms. Canadian Journal of Physiology and Pharmacology 96:9, pages 859-868.
Crossref
Anxin Liu, Weiwei Zhu, Lirui Sun, Guangming Han, Huiping Liu, Zhaoyu Chen, Li Zhuang, Wen Jiang & Xia Xue. (2018) Ginsenoside Rb1 administration attenuates focal cerebral ischemic reperfusion injury through inhibition of HMGB1 and inflammation signals. Experimental and Therapeutic Medicine.
Crossref
Lorena F. Fernandes, Gisele E. Bruch, André R. Massensini & Frédéric Frézard. (2018) Recent Advances in the Therapeutic and Diagnostic Use of Liposomes and Carbon Nanomaterials in Ischemic Stroke. Frontiers in Neuroscience 12.
Crossref
Hyeongmin Kim, Jong Hyuk Lee, Jee Eun Kim, Young Su Kim, Choong Ho Ryu, Hong Joo Lee, Hye Min Kim, Hyojin Jeon, Hyo-Joong Won, Ji-Yun Lee & Jaehwi Lee. (2018) Micro-/nano-sized delivery systems of ginsenosides for improved systemic bioavailability. Journal of Ginseng Research 42:3, pages 361-369.
Crossref
Alexander S. Timin, Maxim M. Litvak, Dmitry A. Gorin, Elena N. Atochina-Vasserman, Dmitriy N. Atochin & Gleb B. Sukhorukov. (2018) Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization. Advanced Healthcare Materials 7:3, pages 1700818.
Crossref
Jie Qiu, Guoqiang Cai, Xinmei Liu & Dongwen Ma. (2017) αvβ3 integrin receptor specific peptide modified, salvianolic acid B and panax notoginsenoside loaded nanomedicine for the combination therapy of acute myocardial ischemia. Biomedicine & Pharmacotherapy 96, pages 1418-1426.
Crossref
Jing-Yan Han, Quan Li, Zhi-Zhong Ma & Jing-Yu Fan. (2017) Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion. Pharmacology & Therapeutics 177, pages 146-173.
Crossref
Xiaowei Shi, Wenjing Yu, Lixing Liu, Wei Liu, Xiaomeng Zhang, Tiantian Yang, Limin Chai, Lixia Lou, Yonghong Gao & Lingqun Zhu. (2016) Panax notoginseng saponins administration modulates pro- /anti-inflammatory factor expression and improves neurologic outcome following permanent MCAO in rats. Metabolic Brain Disease 32:1, pages 221-233.
Crossref
Xiaowei Shi, Wenjing Yu, Tiantian Yang, Wei Liu, Yizhou Zhao, Yikun Sun, Limin Chai, Yonghong Gao, Bin Dong & Lingqun Zhu. (2016) Panax notoginseng saponins provide neuroprotection by regulating NgR1/RhoA/ROCK2 pathway expression, in vitro and in vivo. Journal of Ethnopharmacology 190, pages 301-312.
Crossref
Tatsushi MutohTomoko MutohYasuyuki TakiTatsuya Ishikawa. (2016) Therapeutic Potential of Natural Product-Based Oral Nanomedicines for Stroke Prevention. Journal of Medicinal Food 19:6, pages 521-527.
Crossref
A.M. Cardoso, J.R. Guedes, A.L. Cardoso, C. Morais, P. Cunha, A.T. Viegas, R. Costa, A. Jurado & M.C. Pedroso de Lima. 2016. Nanotechnology and the Brain. Nanotechnology and the Brain 1 40 .
Alice Gaudin, Karine Andrieux & Patrick Couvreur. (2015) Nanomedicines and stroke: Toward translational research. Journal of Drug Delivery Science and Technology 30, pages 278-299.
Crossref
Lijun Zhou, Rong Xing, Lin Xie, Tai Rao, Qian Wang, Wei Ye, Hanxu Fu, Jingcheng Xiao, Yuhao Shao, Dian Kang, Guangji Wang & Yan Liang. (2015) Development and validation of an UFLC–MS/MS assay for the absolute quantitation of nine notoginsenosides in rat plasma: Application to the pharmacokinetic study of Panax Notoginseng Extract. Journal of Chromatography B 995-996, pages 46-53.
Crossref
Peng-Fei Wang, Yu Zhou, Huang Fang, Sen Lin, Yan-Chun Wang, Yong Liu, Jun Xia, Guy D. Eslick & Qing-Wu Yang. (2015) Treatment of acute cerebral ischemia using animal models: a meta-analysis. Translational Neuroscience 6:1, pages 47-58.
Crossref
Palanivel Ganesan, Hyun-Myung Ko, In-Su Kim & Dong-Kug Choi. (2015) Recent trends of nano bioactive compounds from ginseng for its possible preventive role in chronic disease models. RSC Advances 5:119, pages 98634-98642.
Crossref
Kiran S. Panickar. 2015. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease. Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain Disease 3 15 .
Shyamasree Ghosh & Waliza Ansar. 2015. Nanoparticles' Promises and Risks. Nanoparticles' Promises and Risks 167 210 .
Thirumurugan Gunasekaran, Tedesse Haile, Tedele Nigusse & Magharla Dasaratha Dhanaraju. (2014) Nanotechnology: an effective tool for enhancing bioavailability and bioactivity of phytomedicine. Asian Pacific Journal of Tropical Biomedicine 4, pages S1-S7.
Crossref
Peng Zou, Stephan T. Stern & Duxin Sun. (2013) PLGA/Liposome Hybrid Nanoparticles for Short-Chain Ceramide Delivery. Pharmaceutical Research 31:3, pages 684-693.
Crossref
Xian-Si ZengXiao-Shuang ZhouFu-Cheng LuoJin-Jing JiaLei QiZhao-Xiang YangWei ZhangJie Bai. (2014) Comparative analysis of the neuroprotective effects of ginsenosides Rg1 and Rb1 extracted from Panax notoginseng against cerebral ischemia . Canadian Journal of Physiology and Pharmacology 92:2, pages 102-108.
Crossref
Yu Lin, Yun-Fei Wang, Dong-Qun Lin, Jing-Wei Chen, Jun-Zhe Li, Tao-Hua Lan, Ai-Hua Ou & Xin-Min Ruan. (2014) Efficacy and Safety of Huxin Formula in Patients after CABG: A Multicenter, Double-Blind, Randomized Clinical Trial. Complementary Medicine Research 21:6, pages 351-359.
Crossref
Jian-Guo Jiang, Xi-Lin Xu, Si-Bo Zhao & Li Yang. (2022) Macroporous Resin Simultaneously Enriched Flavonoids and Saponins with Antioxidant and Anti-Inflammatory Activitites from Eclipta Prostrata. SSRN Electronic Journal.
Crossref