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Original Research

An MRI-visible non-viral vector for targeted Bcl-2 siRNA delivery to neuroblastoma

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Pages 3319-3332 | Published online: 02 Jul 2012

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Hitesh Jagani, Narayanan Kasinathan, Sreenivasa Reddy Meka & Venkata Rao Josyula. (2016) Antiapoptotic Bcl-2 protein as a potential target for cancer therapy: A mini review. Artificial Cells, Nanomedicine, and Biotechnology 44:5, pages 1212-1221.
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Paulo Jc Lin, Ying Kee Tam & Pieter R Cullis. (2014) Development and clinical applications of siRNA-encapsulated lipid nanoparticles in cancer. Clinical Lipidology 9:3, pages 317-331.
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Jin-Ming Li, Yuan-Yuan Wang, Wei Zhang, Hua Su, Liang-Nian Ji & Zong-Wan Mao. (2013) Low-weight polyethylenimine cross-linked 2-hydroxypopyl-β-cyclodextrin and folic acid as an efficient and nontoxic siRNA carrier for gene silencing and tumor inhibition by VEGF siRNA. International Journal of Nanomedicine 8, pages 2101-2117.
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Articles from other publishers (35)

You-Sheng Lin, Kuen-Song Lin, Yun Chen & Ndumiso Vukile Mdlovu. (2022) Synthesis, characterization, and application of gene conjugated polymerized nitrogen-doped graphene quantum dots carriers for in vivo bio-targeting in neuroblastoma treatment. Journal of the Taiwan Institute of Chemical Engineers 131, pages 104167.
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Madkour Loutfy H. (2021) Imaging modalities delivery of RNAi therapeutics in cancer therapy and clinical applications. Journal of Radiology and Oncology 5:1, pages 005-034.
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Sin Wi Ng, Yinghan Chan, Xin Yi Ng, Kamal Dua & Dinesh Kumar Chellappan. 2021. Advanced Drug Delivery Systems in the Management of Cancer. Advanced Drug Delivery Systems in the Management of Cancer 281 297 .
Sanyog Jain, Kaisar Raza, Ashish Kumar Agrawal & Ankur Vaidya. 2021. Nanotechnology Applications for Cancer Chemotherapy. Nanotechnology Applications for Cancer Chemotherapy 243 270 .
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Praful R. Nair. (2019) Delivering Combination Chemotherapies and Targeting Oncogenic Pathways via Polymeric Drug Delivery Systems. Polymers 11:4, pages 630.
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Yen-Ling Lin, Yu-Chun Lin, Li-Jen Wang, Sin-Ting Ngo & Yunn-Hwa Ma. (2019) Renal perfusion assessment using magnetic nanoparticles with 7T dynamic susceptibility contrast MRI in rats. Journal of Magnetism and Magnetic Materials 475, pages 76-82.
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Janki Shah, Saket Kumar, Mukesh Ranjan, Yogesh Sonvane, Prachi Thareja & Sanjeev K. Gupta. (2018) The effect of filler geometry on thermo-optical and rheological properties of CuO nanofluid. Journal of Molecular Liquids 272, pages 668-675.
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Wondossen Sime, Qiankun Niu, Yasmin Abassi, Katarzyna Chmielarska Masoumi, Reihaneh Zarrizi, Julie Bonne Køhler, Sven Kjellström, Vito Alessandro Lasorsa, Mario Capasso, Haian Fu & Ramin Massoumi. (2018) BAP1 induces cell death via interaction with 14-3-3 in neuroblastoma. Cell Death & Disease 9:5.
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Jianliang Shen, Wei Zhang, Ruogu Qi, Zong-Wan Mao & Haifa Shen. (2018) Engineering functional inorganic–organic hybrid systems: advances in siRNA therapeutics. Chemical Society Reviews 47:6, pages 1969-1995.
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Qixin Leng, Martin C. Woodle & A. James Mixson. (2017) Targeted Delivery of siRNA Therapeutics to Malignant Tumors. Journal of Drug Delivery 2017, pages 1-22.
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Liteng Lin, Mingyue Cai, Shaohui Deng, Wensou Huang, Jingjun Huang, Xinghua Huang, Mingsheng Huang, Yong Wang, Xintao Shuai & Kangshun Zhu. (2017) Amelioration of cirrhotic portal hypertension by targeted cyclooxygenase-1 siRNA delivery to liver sinusoidal endothelium with polyethylenimine grafted hyaluronic acid. Nanomedicine: Nanotechnology, Biology and Medicine 13:7, pages 2329-2339.
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Aili Suo, Junmin Qian, Minghui Xu, Weijun Xu, Yaping Zhang & Yu Yao. (2017) Folate-decorated PEGylated triblock copolymer as a pH/reduction dual-responsive nanovehicle for targeted intracellular co-delivery of doxorubicin and Bcl-2 siRNA. Materials Science and Engineering: C 76, pages 659-672.
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O. S. Vezo, K. G. Gareev, D. V. Korolev, I. A. Kuryshev, S. V. Lebedev, V. A. Moshnikov, E. S. Sergienko & P. V. Kharitonskii. (2017) Aggregate stability and magnetic characteristics of colloidal Fe m O n –SiO2 particles obtained by sol–gel method. Physics of the Solid State 59:5, pages 1008-1013.
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Guimiao Lin, Chih-Kuang Chen, Feng Yin, Chengbin Yang, Jinglin Tian, Ting Chen, Gaixia Xu, Chunxiao He, Marie Chia-Mi Lin, Jie Wang, Fei Lu, Xiaomei Wang & Ken-Tye Yong. (2017) Biodegradable nanoparticles as siRNA carriers for in vivo gene silencing and pancreatic cancer therapy. Journal of Materials Chemistry B 5:18, pages 3327-3337.
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Daniel A. Richards, Antoine Maruani & Vijay Chudasama. (2017) Antibody fragments as nanoparticle targeting ligands: a step in the right direction. Chemical Science 8:1, pages 63-77.
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David B. Rozema. 2017. Platform Technologies in Drug Discovery and Validation. Platform Technologies in Drug Discovery and Validation 17 59 .
Junqing Wang, Peng Mi, Gan Lin, Yì Xiáng J. Wáng, Gang Liu & Xiaoyuan Chen. (2016) Imaging-guided delivery of RNAi for anticancer treatment. Advanced Drug Delivery Reviews 104, pages 44-60.
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M D Kumar, A Dravid, A Kumar & D Sen. (2016) Gene therapy as a potential tool for treating neuroblastoma—a focused review. Cancer Gene Therapy 23:5, pages 115-124.
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Nicholas Fletcher, Aditya Ardana & Kristofer J. Thurecht. (2016) Preclinical Imaging of siRNA Delivery. Australian Journal of Chemistry 69:10, pages 1073.
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Ran Pan, Wen Xu, Feng Yuan, Dafeng Chu, Yong Ding, Baoling Chen, Mousa Jafari, Yongfang Yuan & P. Chen. (2015) A novel peptide for efficient siRNA delivery in vitro and therapeutics in vivo. Acta Biomaterialia 21, pages 74-84.
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James T. Cole & Nolan B. Holland. (2015) Multifunctional nanoparticles for use in theranostic applications. Drug Delivery and Translational Research 5:3, pages 295-309.
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Jin Wang, Linglan Ren, Jingguo Li, Jinsheng Huang, Du Cheng & Xintao Shuai. (2015) Effective siRNA therapy of hepatoma mediated by a nonviral vector with MRI-visibility and biodegradability. RSC Advances 5:27, pages 21103-21111.
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Mamta Kapoor & Diane J. Burgess. 2015. Targeted Drug Delivery : Concepts and Design. Targeted Drug Delivery : Concepts and Design 271 312 .
Rick F. J. Kwekkeboom, Zhiyong Lei, Pieter A. Doevendans, René J. P. Musters & Joost P. G. Sluijter. (2014) Targeted delivery of miRNA therapeutics for cardiovascular diseases: opportunities and challenges. Clinical Science 127:6, pages 351-365.
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M. Videira, A. Arranja, D. Rafael & R. Gaspar. (2014) Preclinical development of siRNA therapeutics: Towards the match between fundamental science and engineered systems. Nanomedicine: Nanotechnology, Biology and Medicine 10:4, pages 689-702.
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Fa-ming Gong, Zuo-quan Zhang, Xiao-dong Chen, Lu Zhang, Xing-su Yu, Qi-hua Yang, Xin-tao Shuai, Bi-ling Liang & Du Cheng. (2014) A dual ligand targeted nanoprobe with high MRI sensitivity for diagnosis of breast cancer. Chinese Journal of Polymer Science 32:3, pages 321-332.
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Mahiuddin Ahmed & Nai-Kong V. Cheung. (2014) Engineering anti-GD2 monoclonal antibodies for cancer immunotherapy. FEBS Letters 588:2, pages 288-297.
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Charles Fortier, Yves Durocher & Gregory De Crescenzo. (2014) Surface modification of nonviral nanocarriers for enhanced gene delivery. Nanomedicine 9:1, pages 135-151.
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Sarah E. Smith & Sara J. Reeder. (2013) What nurse practitioners should know about gene therapy. The Nurse Practitioner 38:11, pages 16-22.
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Pengfei Pang, Chun Wu, Min Shen, Faming Gong, Kangshun Zhu, Zaibo Jiang, Shouhai Guan, Hong Shan & Xintao Shuai. (2013) An MRI-Visible Non-Viral Vector Bearing GD2 Single Chain Antibody for Targeted Gene Delivery to Human Bone Marrow Mesenchymal Stem Cells. PLoS ONE 8:10, pages e76612.
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Sabrina Höbel & Achim Aigner. (2013) Polyethylenimines for siRNA and miRNA delivery in vivo . WIREs Nanomedicine and Nanobiotechnology 5:5, pages 484-501.
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Chun Wu, Faming Gong, Pengfei Pang, Min Shen, Kangshun Zhu, Du Cheng, Zhihao Liu & Hong Shan. (2013) An RGD-Modified MRI-Visible Polymeric Vector for Targeted siRNA Delivery to Hepatocellular Carcinoma in Nude Mice. PLoS ONE 8:6, pages e66416.
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Gang Liu, Jinhao Gao, Hua Ai & Xiaoyuan Chen. (2013) Applications and Potential Toxicity of Magnetic Iron Oxide Nanoparticles. Small 9:9-10, pages 1533-1545.
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Xiaoyong Wang, Zijian Zhou, Zhiyong Wang, Yunxin Xue, Yun Zeng, Jinhao Gao, Lei Zhu, Xianzhong Zhang, Gang Liu & Xiaoyuan Chen. (2013) Gadolinium embedded iron oxide nanoclusters as T1–T2 dual-modal MRI-visible vectors for safe and efficient siRNA delivery. Nanoscale 5:17, pages 8098.
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