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International Journal of Nanomedicine Volume 7, 2012 - Issue
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Original Research

Modification of polyethylene glycol onto solid lipid nanoparticles encapsulating a novel chemotherapeutic agent (PK-L4) to enhance solubility for injection delivery

Yi-Ping Fang1 Department of Biotechnology, Yuanpei University, Hsinchu, Taiwan
,
Pao-Chu Wu2 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
,
Yaw-Bin Huang3 Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
,
Cherng-Chyi Tzeng4 School of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan
,
Yeh-Long Chen4 School of Medicinal and Applied Chemistry, College of Life Science, Kaohsiung Medical University, Kaohsiung, Taiwan
,
Yu-Han Hung2 School of Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, Taiwan
,
Ming-Jun Tsai5 Department of Neurology, China Medical University Hospital, Taichung, Taiwan;6 School of Medicine, Medical College, China Medical University, Taichung, TaiwanCorrespondence[email protected] [email protected]
&
Yi-Hung Tsai3 Graduate Institute of Clinical Pharmacy, College of Pharmacy, Kaohsiung Medical University, Kaohsiung, TaiwanCorrespondence[email protected] [email protected]
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Pages 4995-5005 | Published online: 17 Sep 2012

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Abdelrahman R. Said, Hager S. Zoghroban, Mona F. Arafa, Soheir S. Mahmoud & Gamal M. El Maghraby. (2021) Nanostructured lipid carriers for enhanced in vitro and in vivo schistosomicidal activity of praziquantel: effect of charge. Drug Development and Industrial Pharmacy 47:4, pages 663-672.
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Yi-Ping Fang, Chih-Hung Chuang, Pao-Chu Wu, Yaw-Bin Huang, Cherng-Chyi Tzeng, Yeh-Long Chen, Ya-Ting Liu, Yi-Hung Tsai & Ming-Jun Tsai. (2016) Amsacrine analog-loaded solid lipid nanoparticle to resolve insolubility for injection delivery: characterization and pharmacokinetics. Drug Design, Development and Therapy 10, pages 1019-1028.
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Li-Wen Chang, Mei-Ling Hou, Shuo-Hui Hung, Lie-Chwen Lin & Tung-Hu Tsai. (2015) Pharmacokinetics of quercetin-loaded nanodroplets with ultrasound activation and their use for bioimaging. International Journal of Nanomedicine 10, pages 3031-3042.
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Articles from other publishers (14)

Paola Ruiz Puentes, Maria C. Henao, Javier Cifuentes, Carolina Muñoz-Camargo, Luis H. Reyes, Juan C. Cruz & Pablo Arbeláez. (2022) Rational Discovery of Antimicrobial Peptides by Means of Artificial Intelligence. Membranes 12:7, pages 708.
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Mushfiq Akanda, Giullia Getti, Uttom Nandi, Md Sadeque Mithu & Dennis Douroumis. (2021) Bioconjugated solid lipid nanoparticles (SLNs) for targeted prostate cancer therapy. International Journal of Pharmaceutics 599, pages 120416.
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Tanem Garanti, Mohamed A Alhnan & Ka-Wai Wan. (2020) RGD-decorated solid lipid nanoparticles enhance tumor targeting, penetration and anticancer effect of asiatic acid. Nanomedicine 15:16, pages 1567-1583.
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Nidhi Jyotsana, Amit Sharma, Anuhar Chaturvedi, Ramachandramouli Budida, Michaela Scherr, Florian Kuchenbauer, Robert Lindner, Fatih Noyan, Kurt-Wolfram Sühs, Martin Stangel, Denis Grote-Koska, Korbinian Brand, Hans-Peter Vornlocher, Matthias Eder, Felicitas Thol, Arnold Ganser, R. Keith Humphries, Euan Ramsay, Pieter Cullis & Michael Heuser. (2019) Lipid nanoparticle-mediated siRNA delivery for safe targeting of human CML in vivo. Annals of Hematology 98:8, pages 1905-1918.
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Raj Rai, Saniya Alwani & Ildiko Badea. (2019) Polymeric Nanoparticles in Gene Therapy: New Avenues of Design and Optimization for Delivery Applications. Polymers 11:4, pages 745.
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Bing Wang, Qiangqiang Li, Wei Shi, Li Chen & Jianbo Sun. (2018) Design, synthesis, and cytotoxic evaluation of novel furo[2,3-b]quinoline derivatives. Chemical Biology & Drug Design 91:4, pages 957-961.
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Yu‐Chih Lin, Ming‐Yi Gao, Yi‐Jhun Wu & Yi‐Ping Fang. (2017) Lipid‐enveloped PLGA as a hybrid carrier for sustained delivering camptothecin in ovarian cancer. IET Nanobiotechnology 11:7, pages 797-802.
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Simone M. Vieira, Luana R. Michels, Katiane Roversi, Vinícia G. Metz, Barbra K.S. Moraes, Eduarda M. Piegas, Rodrigo J. Freddo, André Gundel, Teresa Dalla Costa, Marilise E. Burger, Letícia M. Colomé & Sandra E. Haas. (2016) A surface modification of clozapine-loaded nanocapsules improves their efficacy: A study of formulation development and biological assessment. Colloids and Surfaces B: Biointerfaces 145, pages 748-756.
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Jong-Suep Baek, Bo-Sik Kim, Anu Puri, K. Kumar & Cheong-Weon Cho. (2016) Stability of paclitaxel-loaded solid lipid nanoparticles in the presence of 2-hydoxypropyl-β-cyclodextrin. Archives of Pharmacal Research 39:6, pages 785-793.
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Cristiano Farace, Paola Sánchez-Moreno, Marco Orecchioni, Roberto Manetti, Francesco Sgarrella, Yolande Asara, José M. Peula-García, Juan A. Marchal, Roberto Madeddu & Lucia G. Delogu. (2016) Immune cell impact of three differently coated lipid nanocapsules: pluronic, chitosan and polyethylene glycol. Scientific Reports 6:1.
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Apurva R. Patel, Mahavir Chougule & Mandip Singh. (2014) EphA2 Targeting Pegylated Nanocarrier Drug Delivery System for Treatment of Lung Cancer. Pharmaceutical Research 31:10, pages 2796-2809.
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Apurva R. Patel, Mahavir B. Chougule, Ed Lim, Kevin P. Francis, Stephen Safe & Mandip Singh. (2014) Theranostic tumor homing nanocarriers for the treatment of lung cancer. Nanomedicine: Nanotechnology, Biology and Medicine 10:5, pages e1053-e1063.
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Soheila Kashanian & Elham Rostami. (2014) PEG-stearate coated solid lipid nanoparticles as levothyroxine carriers for oral administration. Journal of Nanoparticle Research 16:3.
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Samuel V. Mussi & Vladimir P. Torchilin. (2013) Recent trends in the use of lipidic nanoparticles as pharmaceutical carriers for cancer therapy and diagnostics. Journal of Materials Chemistry B 1:39, pages 5201.
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