Advanced search
Publication Cover
International Journal of Nanomedicine Volume 7, 2012 - Issue
Submit an article Journal homepage
112
Views
19
CrossRef citations to date
0
Altmetric
Original Research

Intracellular CXCR4+ cell targeting with T22-empowered protein-only nanoparticles

Ugutz Unzueta1 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;2 Departamento de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona
,
María Virtudes Céspedes3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona;4 Oncogenesis and Antitumor Drug Group, Biomedical Research Institute Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
,
Neus Ferrer-Miralles1 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;2 Departamento de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona
,
Isolda Casanova3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona;4 Oncogenesis and Antitumor Drug Group, Biomedical Research Institute Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
,
Juan Cedano5 Laboratory of Immunology, Regional Norte, Universidad de la Republica, Salto, Uruguay
,
José Luis Corchero1 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;2 Departamento de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona
,
Joan Domingo-Espín1 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;2 Departamento de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona
,
Antonio Villaverde1 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;2 Departamento de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, BarcelonaCorrespondence[email protected]
,
Ramón Mangues3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona;4 Oncogenesis and Antitumor Drug Group, Biomedical Research Institute Sant Pau, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
&
Esther Vázquez1 Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;2 Departamento de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Barcelona;3 CIBER en Bioingeniería, Biomateriales y Nanomedicina, Bellaterra, Barcelona
 show all
Pages 4533-4544 | Published online: 15 Aug 2012

Citations (19)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Neus Ferrer-Miralles, Escarlata Rodríguez-Carmona, José Luis Corchero, Elena García-Fruitós, Esther Vázquez & Antonio Villaverde. (2015) Engineering protein self-assembling in protein-based nanomedicines for drug delivery and gene therapy. Critical Reviews in Biotechnology 35:2, pages 209-221.
Read now

Articles from other publishers (18)

Meichen Zhang & Haiyan Xu. (2023) Peptide-assembled nanoparticles targeting tumor cells and tumor microenvironment for cancer therapy. Frontiers in Chemistry 11.
Crossref
Giuseppe Bardi. (2022) Chemokines and nanomaterials: interaction for useful immune-applications. Exploration of Immunology, pages 637-647.
Crossref
Esperanza Medina-Gutiérrez, María Virtudes Céspedes, Alberto Gallardo, Elisa Rioja-Blanco, Miquel Àngel Pavón, Laura Asensio-Puig, Lourdes Farré, Lorena Alba-Castellón, Ugutz Unzueta, Antonio Villaverde, Esther Vázquez, Isolda Casanova & Ramon Mangues. (2022) Novel Endometrial Cancer Models Using Sensitive Metastasis Tracing for CXCR4-Targeted Therapy in Advanced Disease. Biomedicines 10:7, pages 1680.
Crossref
Naroa Serna, Aïda Falgàs, Annabel García-León, Ugutz Unzueta, Yáiza Núñez, Alejandro Sánchez-Chardi, Carlos Martínez-Torró, Ramón Mangues, Esther Vazquez, Isolda Casanova & Antonio Villaverde. (2022) Time-Prolonged Release of Tumor-Targeted Protein–MMAE Nanoconjugates from Implantable Hybrid Materials. Pharmaceutics 14:1, pages 192.
Crossref
Ramon Roca-Pinilla, Ravi Holani, Adrià López-Cano, Cristina Saubi, Ricardo Baltà-Foix, Eduardo R. Cobo, Elena Garcia-Fruitós & Anna Arís. (2021) Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins. Scientific Reports 11:1.
Crossref
Naroa Serna, José Vicente Carratalá, Oscar Conchillo-Solé, Carlos Martínez-Torró, Ugutz Unzueta, Ramón Mangues, Neus Ferrer-Miralles, Xavier Daura, Esther Vázquez & Antonio Villaverde. (2021) Antibacterial Activity of T22, a Specific Peptidic Ligand of the Tumoral Marker CXCR4. Pharmaceutics 13:11, pages 1922.
Crossref
Olivia Cano-Garrido, Patricia Álamo, Laura Sánchez-García, Aïda Falgàs, Alejandro Sánchez-Chardi, Naroa Serna, Eloi Parladé, Ugutz Unzueta, Mònica Roldán, Eric Voltà-Durán, Isolda Casanova, Antonio Villaverde, Ramón Mangues & Esther Vázquez. (2021) Biparatopic Protein Nanoparticles for the Precision Therapy of CXCR4+ Cancers. Cancers 13:12, pages 2929.
Crossref
Zeeshan Javed, Muhammad Javed Iqbal, Amna Rasheed, Haleema Sadia, Shahid Raza, Asma Irshad, Wojciech Koch, Wirginia Kukula-Koch, Anna Głowniak-Lipa, William C. Cho & Javad Sharifi-Rad. (2021) Regulation of Hedgehog Signaling by miRNAs and Nanoformulations: A Possible Therapeutic Solution for Colorectal Cancer. Frontiers in Oncology 10.
Crossref
Anissa Pisani, Roberto Donno, Arianna Gennari, Giulia Cibecchini, Federico Catalano, Roberto Marotta, Pier Paolo Pompa, Nicola Tirelli & Giuseppe Bardi. (2020) CXCL12-PLGA/Pluronic Nanoparticle Internalization Abrogates CXCR4-Mediated Cell Migration. Nanomaterials 10:11, pages 2304.
Crossref
Patricia Álamo, Victor Pallarès, María Virtudes Céspedes, Aïda Falgàs, Julieta M. Sanchez, Naroa Serna, Laura Sánchez-García, Eric Voltà-Duràn, Gordon A. Morris, Alejandro Sánchez-Chardi, Isolda Casanova, Ramón Mangues, Esther Vazquez, Antonio Villaverde & Ugutz Unzueta. (2020) Fluorescent Dye Labeling Changes the Biodistribution of Tumor-Targeted Nanoparticles. Pharmaceutics 12:11, pages 1004.
Crossref
Ping Yang, Yae Hu & Quansheng Zhou. (2020) The CXCL12-CXCR4 Signaling Axis Plays a Key Role in Cancer Metastasis and is a Potential Target for Developing Novel Therapeutics against Metastatic Cancer. Current Medicinal Chemistry 27:33, pages 5543-5561.
Crossref
Hèctor López-Laguna, Rafael Cubarsi, Ugutz Unzueta, Ramón Mangues, Esther Vázquez & Antonio Villaverde. (2019) Endosomal escape of protein nanoparticles engineered through humanized histidine-rich peptides. Science China Materials 63:4, pages 644-653.
Crossref
Zhen Luo, Fengze Miao, Menghong Hu & Youji Wang. (2020) Research Development on Horseshoe Crab: A 30-Year Bibliometric Analysis. Frontiers in Marine Science 7.
Crossref
Eric Voltà-Durán, Olivia Cano-Garrido, Naroa Serna, Hèctor López-Laguna, Laura Sánchez-García, Mireia Pesarrodona, Alejandro Sánchez-Chardi, Ramón Mangues, Antonio Villaverde, Esther Vázquez & Ugutz Unzueta. (2019) Controlling self-assembling and tumor cell-targeting of protein-only nanoparticles through modular protein engineering. Science China Materials 63:1, pages 147-156.
Crossref
Naroa Serna, Julieta M Sánchez, Ugutz Unzueta, Laura Sánchez-García, Alejandro Sánchez-Chardi, Ramón Mangues, Esther Vázquez & Antonio Villaverde. (2019) Recruiting potent membrane penetrability in tumor cell-targeted protein-only nanoparticles. Nanotechnology 30:11, pages 115101.
Crossref
Sara Cabrero-de las Heras & Eva Martínez-Balibrea. (2018) CXC family of chemokines as prognostic or predictive biomarkers and possible drug targets in colorectal cancer. World Journal of Gastroenterology 24:42, pages 4738-4749.
Crossref
Julieta M. Sánchez, Laura Sánchez-García, Mireia Pesarrodona, Naroa Serna, Alejandro Sánchez-Chardi, Ugutz Unzueta, Ramón Mangues, Esther Vázquez & Antonio Villaverde. (2018) Conformational Conversion during Controlled Oligomerization into Nonamylogenic Protein Nanoparticles. Biomacromolecules 19:9, pages 3788-3797.
Crossref
Ugutz Unzueta, Joaquin Seras-Franzoso, María Virtudes Céspedes, Paolo Saccardo, Francisco Cortés, Fabián Rueda, Elena Garcia-Fruitós, Neus Ferrer-Miralles, Ramon Mangues, Esther Vázquez & Antonio Villaverde. (2017) Engineering tumor cell targeting in nanoscale amyloidal materials. Nanotechnology 28:1, pages 015102.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.