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International Journal of Nanomedicine Volume 17, 2023 - Issue
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Original Research

Hydroxyl Group-Targeted Conjugate and Its Self-Assembled Nanoparticle of Peptide Drug: Effect of Degree of Saturation of Fatty Acids and Modification of Physicochemical Properties

Jisoo Park1 Bioavailability Control Laboratory, College of Pharmacy, Ajou University, Suwon, 16499, Republic of Korea
,
Hai V Ngo1 Bioavailability Control Laboratory, College of Pharmacy, Ajou University, Suwon, 16499, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-5161-7911
ORCID Icon,
Hyo-Eon Jin1 Bioavailability Control Laboratory, College of Pharmacy, Ajou University, Suwon, 16499, Republic of KoreaORCID Iconhttps://orcid.org/0000-0002-1292-5508
ORCID Icon,
Kye Wan Lee2 Dongkook Pharmaceutical Co., Ltd, Seoul, Republic of Korea
&
Beom-Jin Lee1 Bioavailability Control Laboratory, College of Pharmacy, Ajou University, Suwon, 16499, Republic of KoreaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-0922-3289
ORCID Icon
Pages 2243-2260 | Published online: 17 May 2022

Citations (6)

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Read on this site (2)

Hy D Nguyen, Hai V Ngo, Van Hong Nguyen, Myung-Chul Gil & Beom-Jin Lee. (2023) Roles of Fatty Acid Chain Length and Enzyme-Oriented Drug Controlled Release from pH-Triggering Self-Assembled Fatty Acid Conjugated Quetiapine Nanosuspensions. International Journal of Nanomedicine 18, pages 7115-7131.
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Hai V Ngo, Hye-Eun Bak, Hy D Nguyen, Kye Wan Lee, Chulhun Park & Beom-Jin Lee. (2023) Physicochemical and Biopharmaceutical Controllability of New Self-Assembled Fatty Acid Conjugated Leuprolide for the Enhanced Anticancer Activity. International Journal of Nanomedicine 18, pages 2325-2344.
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Articles from other publishers (4)

Hyomin Jin, Hai V. Ngo, Chulhun Park & Beom-Jin Lee. (2023) Mucoadhesive buccal tablet of leuprolide and its fatty acid conjugate: Design, in vitro evaluation and formulation strategies. International Journal of Pharmaceutics 639, pages 122963.
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Mohamed Mahmoud Ali, Raguia Aly Shoukri & Carol Yousry. (2022) Thin film hydration versus modified spraying technique to fabricate intranasal spanlastic nanovesicles for rasagiline mesylate brain delivery: Characterization, statistical optimization, and in vivo pharmacokinetic evaluation. Drug Delivery and Translational Research 13:4, pages 1153-1168.
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Gi-Sang Seong, Seong-Wook Seo, Ji Young Cho, Kye Wan Lee, Beom-Jin Lee, In-Soo Yoon & Hyo-Eon Jin. (2022) Determination of Leuprolide–Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats. Molecules 27:24, pages 8716.
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Mahmoud H. Teaima, Doaa A. Helal, Jihad M. Alsofany, Mohamed A. El-Nabarawi & Mohamed Yasser. (2022) Ion-Triggered In Situ Gelling Intranasal Spray of Dronedarone Hydrochloride Nanocarriers: In Vitro Optimization and In Vivo Pharmacokinetic Appraisal. Pharmaceutics 14:11, pages 2405.
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