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Original Research

The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility

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Pages 5757-5768 | Published online: 12 Nov 2012

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Read on this site (7)

Andreas Schittny, Jörg Huwyler & Maxim Puchkov. (2020) Mechanisms of increased bioavailability through amorphous solid dispersions: a review. Drug Delivery 27:1, pages 110-127.
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Sophia Yui Kau Fong, Annette Bauer-Brandl & Martin Brandl. (2017) Oral bioavailability enhancement through supersaturation: an update and meta-analysis. Expert Opinion on Drug Delivery 14:3, pages 403-426.
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Silvana A. Barea, Cristiane B. Mattos, Ariadne C. C. Cruz, Vitor C. Chaves, Rafael N. Pereira, Claudia M. O. Simões, Jadel M. Kratz & Letícia S. Koester. (2017) Solid dispersions enhance solubility, dissolution, and permeability of thalidomide. Drug Development and Industrial Pharmacy 43:3, pages 511-518.
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Shashank Jain, Niketkumar Patel & Senshang Lin. (2015) Solubility and dissolution enhancement strategies: current understanding and recent trends. Drug Development and Industrial Pharmacy 41:6, pages 875-887.
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Bo Lang, James W. McGinity & Robert O. Williams$suffix/text()$suffix/text(). (2014) Hot-melt extrusion – basic principles and pharmaceutical applications. Drug Development and Industrial Pharmacy 40:9, pages 1133-1155.
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Articles from other publishers (7)

Gayathri Ramachandran & M. S. Sudheesh. (2021) Role of Permeability on the Biopredictive Dissolution of Amorphous Solid Dispersions. AAPS PharmSciTech 22:7.
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Sugandha Saboo, Pradnya Bapat, Dana Moseson, Umesh Kestur & Lynne Taylor. (2021) Exploring the Role of Surfactants in Enhancing Drug Release from Amorphous Solid Dispersions at Higher Drug Loadings. Pharmaceutics 13:5, pages 735.
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Frank Theil, Johanna Milsmann, Sankaran Anantharaman & Holger van Lishaut. (2018) Manufacturing Amorphous Solid Dispersions with a Tailored Amount of Crystallized API for Biopharmaceutical Testing. Molecular Pharmaceutics 15:5, pages 1870-1877.
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Paul Harmon, Kendra Galipeau, Wei Xu, Chad Brown & W. Peter Wuelfing. (2016) Mechanism of Dissolution-Induced Nanoparticle Formation from a Copovidone-Based Amorphous Solid Dispersion. Molecular Pharmaceutics 13:5, pages 1467-1481.
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Luis Almeida e Sousa, Susan M. Reutzel-Edens, Gregory A. Stephenson & Lynne S. Taylor. (2016) Supersaturation Potential of Salt, Co-Crystal, and Amorphous Forms of a Model Weak Base. Crystal Growth & Design 16:2, pages 737-748.
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Shunsuke Kimura, Sachiha Kasatani, Megumi Tanaka, Kaeko Araki, Masakazu Enomura, Kei Moriyama, Daisuke Inoue, Tomoyuki Furubayashi, Akiko Tanaka, Kosuke Kusamori, Hidemasa Katsumi, Toshiyasu Sakane & Akira Yamamoto. (2015) Importance of the Direct Contact of Amorphous Solid Particles with the Surface of Monolayers for the Transepithelial Permeation of Curcumin. Molecular Pharmaceutics 13:2, pages 493-499.
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Cameron Ball & Kim A. Woodrow. (2014) Electrospun Solid Dispersions of Maraviroc for Rapid Intravaginal Preexposure Prophylaxis of HIV. Antimicrobial Agents and Chemotherapy 58:8, pages 4855-4865.
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