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International Journal of Nanomedicine Volume 18, 2023 - Issue
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ORIGINAL RESEARCH

Disulfide Bond-Based SN38 Prodrug Nanoassemblies with High Drug Loading and Reduction-Triggered Drug Release for Pancreatic Cancer Therapy

Zhi-Xin Zhong1 School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People’s Republic of China
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Xu-Zhao Li1 School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People’s Republic of China
,
Jin-Tao Liu1 School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People’s Republic of China
,
Nan Qin1 School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People’s Republic of China
,
Hong-Quan Duan1 School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People’s Republic of China;2 Research Center of Basic Medical Sciences, Tianjin Medical University, Tianjin, 300070, People’s Republic of China;3 Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), Tianjin Medical University, Tianjin, 300070, People’s Republic of ChinaCorrespondence[email protected] [email protected]
&
Xiao-Chuan Duan1 School of Pharmacy, Tianjin Medical University, Tianjin, 300070, People’s Republic of China;4 School of Biomedical Engineering and Technology, Tianjin Medical University, Tianjin, 300070, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-5677-8135
ORCID Icon
Pages 1281-1298 | Received 25 Jan 2023, Accepted 11 Mar 2023, Published online: 15 Mar 2023

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Qing-rui Qi, Huan Tian, Bao-sen Yue, Bing-tao Zhai & Feng Zhao. (2024) Research Progress of SN38 Drug Delivery System in Cancer Treatment. International Journal of Nanomedicine 19, pages 945-964.
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Mei Cong, Houjun Pang, Guangxing Xie, Feifei Li, Chunxiao Li, Hao Sun, Shaoyou Yang & Weidong Zhao. (2023) Engineering of Amphiphilic Erlotinib Analogue as Novel Nanomedicine for Non-Small Cell Lung Cancer Therapy. International Journal of Nanomedicine 18, pages 6367-6377.
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Tahta Amrillah, Bintang Adji Notodidjojo, Mohammad Kalimanjaro, Rangga Adhi Prastika, Azka Muhammad Nurrahman, Ahmad Taufiq, Djoko Santoso & Dwi Setyawan. (2024) Crafting Iron Oxides for Next-Generation Biomedical Applications. Crystal Growth & Design 24:13, pages 5834-5864.
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Chengzhen Pan, Chi Zhang, Zonghan Lin, Zhou Liang, Yinhang Cui, Zhihao Shang, Yuanxun Wei & Feng Chen. (2024) Disulfidptosis-related Protein RPN1 may be a Novel Anti-osteoporosis Target of Kaempferol. Combinatorial Chemistry & High Throughput Screening 27:11, pages 1611-1628.
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Nuo Li, Ludan Zhang, Kaijun Sun, Junheng Liu, Zixuan Wang, Yujing Wang, Huinan Lu, Wenjun Xiang, Hailin Yang, Rupei Tang & Guoqing Yan. (2024) pH-Sensitive Nanodrug Self-Assembled from Aliphatic 5-Fluorouracil Derivative and Doxorubicin for Synergistic Cancer Therapy. ACS Applied Nano Materials 7:9, pages 10419-10428.
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Debojit Chakraborty, Anindita Sengupta, Jayanta Bhattacharyya & Josemon Jacob. (2024) Facile synthesis and polymerization of 1,4,5-oxadithiepan-2-one for disulfide-based redox-responsive drug delivery. Polymer 298, pages 126920.
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Matilde Tubertini, Luca Menilli, Celeste Milani, Cecilia Martini, Maria Luisa Navacchia, Marta Nugnes, Manuela Bartolini, Marina Naldi, Daniele Tedesco, Elisa Martella, Andrea Guerrini, Claudia Ferroni, Francesca Moret & Greta Varchi. (2024) HSA-nanobinders crafted from bioresponsive prodrugs for combined cancer chemoimmunotherapy–an in vitro exploration. Frontiers in Chemistry 12.
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Yanhua Zhang, Hui Xu, Yue Li, Yang Sun & Xiaochun Peng. (2023) Advances in the treatment of pancreatic cancer with traditional Chinese medicine. Frontiers in Pharmacology 14.
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Yi Dai, Meng Qian & Yan Li. (2023) Structural Modification Endows Small-Molecular SN38 Derivatives with Multifaceted Functions. Molecules 28:13, pages 4931.
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