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International Journal of Nanomedicine Volume 9, 2014 - Issue sup2
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Original Research

Evaluation of silica nanoparticle toxicity after topical exposure for 90 days

Hwa Jung Ryu1 Department of Dermatology, Korea University College of Medicine, Seoul, South Korea
,
Nak-won Seong2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Byoung Joon So1 Department of Dermatology, Korea University College of Medicine, Seoul, South Korea
,
Heung-sik Seo2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Jun-ho Kim2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Jeong-Sup Hong2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Myeong-kyu Park2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Min-Seok Kim2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Yu-Ri Kim3 Department of Biochemistry and Molecular Biology, Korea University College of Medicine, Seoul, South Korea
,
Kyu-Bong Cho4 Department of Clinical Laboratory Science, Shinheung College, Uijeongbu, South Korea
,
Mu Yeb Seo2 Korea Testing and Research Institute, Gyunggi-Do, South Korea
,
Meyoung-Kon Kim3 Department of Biochemistry and Molecular Biology, Korea University College of Medicine, Seoul, South Korea
,
Eun Ho Maeng2 Korea Testing and Research Institute, Gyunggi-Do, South KoreaCorrespondence[email protected]
&
Sang Wook Son1 Department of Dermatology, Korea University College of Medicine, Seoul, South KoreaCorrespondence[email protected]
 show all
Pages 127-136 | Published online: 15 Dec 2014

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Walter Brand, Petra C. E. van Kesteren, Ruud J. B. Peters & Agnes G. Oomen. (2021) Issues currently complicating the risk assessment of synthetic amorphous silica (SAS) nanoparticles after oral exposure. Nanotoxicology 15:7, pages 905-933.
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Ruud J. B. Peters, Agnes G. Oomen, Greet van Bemmel, Loes van Vliet, Anna K. Undas, Sandra Munniks, Ronald L. A. W. Bleys, Peter C. Tromp, Walter Brand & Martijn van der Lee. (2020) Silicon dioxide and titanium dioxide particles found in human tissues. Nanotoxicology 14:3, pages 420-432.
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Menglei Wang, Xuan Lai, Longquan Shao & Li Li. (2018) Evaluation of immunoresponses and cytotoxicity from skin exposure to metallic nanoparticles. International Journal of Nanomedicine 13, pages 4445-4459.
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Mansour Almansour, Saud Alarifi & Bashir Jarrar. (2018) In vivo investigation on the chronic hepatotoxicity induced by intraperitoneal administration of 10-nm silicon dioxide nanoparticles. International Journal of Nanomedicine 13, pages 2685-2696.
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Pejman Mohammadi, Marzieh Abbasinia, Mohammad Javad Assari & Mohammad Oliaei. (2018) The Toxicology of Silica Nanoparticles: A Review. Toxicological & Environmental Chemistry 100:3, pages 285-316.
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Articles from other publishers (19)

Nicolas Touya, Ayako Washio, Chiaki Kitamura, Adrien Naveau, Yasuhiko Tabata, Raphaël Devillard & Olivia Kérourédan. (2022) In Vivo Application of Silica-Derived Inks for Bone Tissue Engineering: A 10-Year Systematic Review. Bioengineering 9:8, pages 388.
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Taghrid Zaiter, Raphaël Cornu, Wassim El Basset, Hélène Martin, Mona Diab & Arnaud Béduneau. (2022) Toxicity assessment of nanoparticles in contact with the skin. Journal of Nanoparticle Research 24:7.
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Júlia Sala-Jarque, Elisa García-Lara, Paula Carreras-Domínguez, Chunfang Zhou, Neus Rabaneda-Lombarte, Carme Solà, Jose M Vidal-Taboada, Adam Feiler, Ninnie Abrahamsson, Elena N Kozlova & Josep Saura. (2022) Mesoporous silica particles are phagocytosed by microglia and induce a mild inflammatory response in vitro . Nanomedicine 17:15, pages 1077-1094.
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Iman Fatima, Akhtar Rasul, Shahid Shah, Malik Saadullah, Nayyer Islam, Ahmed Khames, Ahmad Salawi, Muhammad Masood Ahmed, Yosif Almoshari, Ghulam Abbas, Mohammed A. S. Abourehab, Sajid Mehmood Khan, Zunera Chauhdary, Meshal Alshamrani, Nader Ibrahim Namazi & Demiana M. Naguib. (2022) Novasomes as Nano-Vesicular Carriers to Enhance Topical Delivery of Fluconazole: A New Approach to Treat Fungal Infections. Molecules 27:9, pages 2936.
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Akhela Umapathi, Mamta Kumawat & Hemant Kumar Daima. (2021) Engineered nanomaterials for biomedical applications and their toxicity: a review. Environmental Chemistry Letters 20:1, pages 445-468.
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Valeria De Matteis, Mariafrancesca Cascione, Agnese De Luca, Daniela Erminia Manno & Rosaria Rinaldi. (2022) High Doses of Silica Nanoparticles Obtained by Microemulsion and Green Routes Compromise Human Alveolar Cells Morphology and Stiffness Differently. Bioinorganic Chemistry and Applications 2022, pages 1-23.
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Ana S. Macedo, Francisca Mendes, Patrícia Filipe, Salette Reis & Pedro Fonte. (2021) Nanocarrier-Mediated Topical Insulin Delivery for Wound Healing. Materials 14:15, pages 4257.
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Vânia Vilas-Boas & Mathieu Vinken. (2020) Hepatotoxicity induced by nanomaterials: mechanisms and in vitro models. Archives of Toxicology 95:1, pages 27-52.
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Suchetha Muniraju, S. Pradeep, Chandraprasad Madihalli, J. P. Shabaaz Begum & K. J. Thara Saraswathi. (2020) Nanostructured silica particles from Cymbopogon flexuosus (Nees ex Steud.): extraction, characterization and study of their blend with osteoporotic drugs. SN Applied Sciences 2:12.
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Barbara Vörös-Horváth, Sourav Das, Ala’ Salem, Sándor Nagy, Andrea Böszörményi, Tamás Kőszegi, Szilárd Pál & Aleksandar Széchenyi. (2020) Formulation of Tioconazole and Melaleuca alternifolia Essential Oil Pickering Emulsions for Onychomycosis Topical Treatment. Molecules 25:23, pages 5544.
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Gwang-Hoon Lee, Yun-Soon Kim, Euna Kwon, Jun-Won Yun & Byeong-Cheol Kang. (2020) Toxicologic Evaluation for Amorphous Silica Nanoparticles: Genotoxic and Non-Genotoxic Tumor-Promoting Potential. Pharmaceutics 12:9, pages 826.
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Vanitha Selvarajan, Sybil Obuobi & Pui Lai Rachel Ee. (2020) Silica Nanoparticles—A Versatile Tool for the Treatment of Bacterial Infections. Frontiers in Chemistry 8.
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Min Li, Fang Cheng, Changying Xue, Hanqi Wang, Chen Chen, Qiqi Du, Dan Ge & Bingbing Sun. (2019) Surface Modification of Stöber Silica Nanoparticles with Controlled Moiety Densities Determines Their Cytotoxicity Profiles in Macrophages. Langmuir 35:45, pages 14688-14695.
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Brian C. Palmer, Samreen Jatana, Sarah J. Phelan-Dickinson & Lisa A. DeLouise. (2019) Amorphous silicon dioxide nanoparticles modulate immune responses in a model of allergic contact dermatitis. Scientific Reports 9:1.
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Rafael Carlos Lajmanovich, Paola Mariela Peltzer, Candela Soledad Martinuzzi, Andrés Maximiliano Attademo, Carlina Leila Colussi & Agustín Bassó. (2018) Acute Toxicity of Colloidal Silicon Dioxide Nanoparticles on Amphibian Larvae: Emerging Environmental Concern. International Journal of Environmental Research 12:3, pages 269-278.
Crossref
Sivakumar Murugadoss, Dominique Lison, Lode Godderis, Sybille Van Den Brule, Jan Mast, Frederic Brassinne, Noham Sebaihi & Peter H. Hoet. (2017) Toxicology of silica nanoparticles: an update. Archives of Toxicology 91:9, pages 2967-3010.
Crossref
Martha Kim, Joo-Hee Park, Hyejoong Jeong, Jinkee Hong, Woo Sung Choi, Byung-Han Lee & Choul Yong Park. (2017) An Evaluation of the in vivo Safety of Nonporous Silica Nanoparticles: Ocular Topical Administration versus Oral Administration. Scientific Reports 7:1.
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Raymond Ebabe Elle, Saher Rahmani, Céline Lauret, Marion Morena, Luc Philippe Régis Bidel, Abdelhay Boulahtouf, Patrick Balaguer, Jean-Paul Cristol, Jean-Olivier Durand, Clarence Charnay & Eric Badia. (2016) Functionalized Mesoporous Silica Nanoparticle with Antioxidants as a New Carrier That Generates Lower Oxidative Stress Impact on Cells. Molecular Pharmaceutics 13:8, pages 2647-2660.
Crossref
Sanae Kanno. 2016. Biological Effects of Fibrous and Particulate Substances. Biological Effects of Fibrous and Particulate Substances 27 50 .

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