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International Journal of Nanomedicine Volume 10, 2015 - Issue
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Original Research

Chitosan/siRNA functionalized titanium surface via a layer-by-layer approach for in vitro sustained gene silencing and osteogenic promotion

Wen Song1 State Key Laboratory of Military Stomatology, Department of Prosthetic Dentistry, School of Stomatology, The Fourth Military Medical University, Xi’an, People’s Republic of China
,
Xin Song2 Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark
,
Chuanxu Yang2 Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark
,
Shan Gao2 Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark
,
Lasse Hyldgaard Klausen2 Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark
,
Yumei Zhang1 State Key Laboratory of Military Stomatology, Department of Prosthetic Dentistry, School of Stomatology, The Fourth Military Medical University, Xi’an, People’s Republic of ChinaCorrespondence[email protected]
,
Mingdong Dong2 Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark
&
Jørgen Kjems2 Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, DenmarkCorrespondence[email protected]
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Pages 2335-2346 | Published online: 24 Mar 2015

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Jiahao Tang, Liang Chen, Deyi Yan, Zijian Shen, Bingzhang Wang, Sheji Weng, Zongyi Wu, Zhongjie Xie, Jiancan Shao, Lei Yang & Liyan Shen. (2020) Surface Functionalization with Proanthocyanidins Provides an Anti-Oxidant Defense Mechanism That Improves the Long-Term Stability and Osteogenesis of Titanium Implants. International Journal of Nanomedicine 15, pages 1643-1659.
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Liangrui Chen, Mingxuan Bai, Ruiyu Du, Hao Wang, Yi Deng, Anqi Xiao & Xueqi Gan. (2020) The non-viral vectors and main methods of loading siRNA onto the titanium implants and their application. Journal of Biomaterials Science, Polymer Edition 31:16, pages 2152-2168.
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Shuhei Tsuchiya, Keisuke Sugimoto, Hisanobu Kamio, Kazuto Okabe, Kensuke Kuroda, Masazumi Okido & Hideharu Hibi. (2018) Kaempferol-immobilized titanium dioxide promotes formation of new bone: effects of loading methods on bone marrow stromal cell differentiation in vivo and in vitro. International Journal of Nanomedicine 13, pages 1665-1676.
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Zhenlin Wang, Zhiqiang Hu, Dawei Zhang, Mengchuan Zhuo, Jiwei Cheng, Xingping Xu, Yongming Xing & Jie Fan. (2016) Silencing tumor necrosis factor-alpha in vitro from small interfering RNA-decorated titanium nanotube array can facilitate osteogenic differentiation of mesenchymal stem cells. International Journal of Nanomedicine 11, pages 3205-3214.
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Articles from other publishers (8)

Wen Han, Shuobo Fang, Qun Zhong & Shengcai Qi. (2022) Influence of Dental Implant Surface Modifications on Osseointegration and Biofilm Attachment. Coatings 12:11, pages 1654.
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Sen Jia, Yan Liu, Zhiwei Ma, Changkui Liu, Juan Chai, Zixia Li, Wen Song & Kaijin Hu. (2021) A novel vertical aligned mesoporous silica coated nanohydroxyapatite particle as efficient dexamethasone carrier for potential application in osteogenesis. Biomedical Materials 16:3, pages 035030.
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Heng Dong, Hui Liu, Na Zhou, Qiang Li, Guangwen Yang, Li Chen & Yongbin Mou. (2020) Surface Modified Techniques and Emerging Functional Coating of Dental Implants. Coatings 10:11, pages 1012.
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Ghadeer Falah, Abram Giller, Danielle Gutman & Gil Atzmon. (2020) Breaking the Glass Ceiling. Gerontology 66:4, pages 309-314.
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Biao Hu, Liangzhe Chen, Shuang Lan, Ping Ren, Si Wu, Xinghai Liu, Xiaowen Shi, Houbin Li, Yumin Du & Fuyuan Ding. (2018) Layer-by-Layer Assembly of Polysaccharide Films with Self-Healing and Antifogging Properties for Food Packaging Applications. ACS Applied Nano Materials 1:7, pages 3733-3740.
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Wen Song, Chuanxu Yang, Dang Quang Svend Le, Yumei Zhang & Jørgen Kjems. (2018) Calcium–MicroRNA Complex-Functionalized Nanotubular Implant Surface for Highly Efficient Transfection and Enhanced Osteogenesis of Mesenchymal Stem Cells. ACS Applied Materials & Interfaces 10:9, pages 7756-7764.
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Quan Shi, Zhiyong Qian, Donghua Liu & Hongchen Liu. (2017) Surface Modification of Dental Titanium Implant by Layer-by-Layer Electrostatic Self-Assembly. Frontiers in Physiology 8.
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Bita Sedaghati, Jan Hoyer, Achim Aigner, Michael C. Hacker & Michaela Schulz-Siegmund. 2016. Regenerative Medicine - from Protocol to Patient. Regenerative Medicine - from Protocol to Patient 185 210 .

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