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Original Research

Nanoalumina induces apoptosis by impairing antioxidant enzyme systems in human hepatocarcinoma cells

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Pages 3751-3760 | Published online: 25 May 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Hanouf Almukhlafi, Daoud Ali, Bader Almutairi, Khadijah N Yaseen, Nouf Alyami, Rafa Almeer, Saad Alkahtani & Saud Alarifi. (2021) Role of Oxidative Stress in La2O3 Nanoparticle-Induced Cytotoxicity and Apoptosis in CHANG and HuH-7 Cells. International Journal of Nanomedicine 16, pages 3487-3496.
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Vladimir V. Chrishtop, Vladimir A. Mironov, Artur Y. Prilepskii, Varvara G. Nikonorova & Vladimir V. Vinogradov. (2021) Organ-specific toxicity of magnetic iron oxide-based nanoparticles. Nanotoxicology 15:2, pages 167-204.
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May Bin-Jumah, Monera AL-Abdan, Gadah Albasher & Saud Alarifi. (2020) Effects of Green Silver Nanoparticles on Apoptosis and Oxidative Stress in Normal and Cancerous Human Hepatic Cells in vitro. International Journal of Nanomedicine 15, pages 1537-1548.
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Jéssica Schveitzer Köerich, Diego José Nogueira, Vitor Pereira Vaz, Carmen Simioni, Marlon Luiz Neves Da Silva, Luciane Cristina Ouriques, Denice Schulz Vicentini & William Gerson Matias. (2020) Toxicity of binary mixtures of Al2O3 and ZnO nanoparticles toward fibroblast and bronchial epithelium cells. Journal of Toxicology and Environmental Health, Part A 83:9, pages 363-377.
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Daoud Ali, Saud Alarifi, Saad Alkahtani & Rafa S Almeer. (2018) Silver-doped graphene oxide nanocomposite triggers cytotoxicity and apoptosis in human hepatic normal and carcinoma cells. International Journal of Nanomedicine 13, pages 5685-5699.
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Saud Alarifi, Huma Ali, Saad Alkahtani & Mohammed S Alessia. (2017) Regulation of apoptosis through bcl-2/bax proteins expression and DNA damage by nano-sized gadolinium oxide. International Journal of Nanomedicine 12, pages 4541-4551.
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Articles from other publishers (13)

Sepehr Darvishan, Mehrab Pourmadadi, Majid Abdouss, Saeedeh Mazinani, Fatemeh Yazdian, Abbas Rahdar & Ana M. Díez-Pascual. (2023) Gamma alumina coated-PAA/PVP hydrogel as promising quercetin nanocarrier: Physiochemical characterization and toxicity activity. Journal of Drug Delivery Science and Technology 84, pages 104500.
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Melnikova Anzhelika, Kirkin Roman & Komarova Luidmila. (2023) Optimization of the kinetics of siRNA desorption from the surface of silicon nanoparticles. Annals of Biomedical Science and Engineering 7:1, pages 020-023.
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Gobichettipalayam Balasubramaniam Maadurshni, Ganeshmurthy Kanniamal Tharani, Inbamani Udayakumar, Manigandan Nagarajan & Jeganathan Manivannan. (2022) Al2O3 nanoparticles trigger the embryonic hepatotoxic response and potentiate TNF-α-induced apoptosis—modulatory effect of p38 MAPK and JNK inhibitors. Environmental Science and Pollution Research 29:36, pages 54250-54263.
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Nermeen B. El‐Borai, Basma A. Elkhadrawey, Huda O. AbuBakr, Anis Anis, Badr E. El‐Bialy, Hesham S. Elsabbagh & Shimaa M. Abou‐Zeid. (2022) Sesamol protects against aluminum oxide nanoparticles‐induced hepatorenal toxicity in rats via modulation of oxidative stress, inflammation, apoptosis, and DNA damage . Environmental Toxicology 37:8, pages 1914-1924.
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Hadeel A. Almasoud, Daoud Ali, Khadijah N. Yaseen, Hanouf Almukhlafi, Norah S. Alothman, Bader Almutairi, Rafa Almeer, Nouf Alyami, Saad Alkahtani & Saud Alarifi. (2022) Dose-Dependent Variation in Anticancer Activity of Hexane and Chloroform Extracts of Field Horsetail Plant on Human Hepatocarcinoma Cells. BioMed Research International 2022, pages 1-8.
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A. D. Khalid, N. -ur-Rehman, F. Hadi, S. S. Iqbal, S. A. Buzdar & A. K. Khan. (2022) Cytotoxicity of zinc oxide nanoparticles coupled with folic acid and polyethylene glycol. Digest Journal of Nanomaterials and Biostructures 17:1, pages 73-79.
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Sofía Navarro Espinoza, Diana Meza-Figueroa, Diego Soto-Puebla, Beatriz Castañeda & Martín Pedroza-Montero. (2021) NANOPARTÍCULAS: EFECTOS EN LA SALUD HUMANA Y EL MEDIO AMBIENTE. EPISTEMUS 15:30.
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Bader Almutairi, Daoud Ali, Khadijah N. Yaseen, Norah S. Alothman, Nouf Alyami, Hanouf Almukhlafi, Saad Alakhtani & Saud Alarifi. (2021) Mechanisms of Apoptotic Cell Death by Stainless Steel Nanoparticle Through Reactive Oxygen Species and Caspase-3 Activities on Human Liver Cells. Frontiers in Molecular Biosciences 8.
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Monera A. Al-Abdan, May N. Bin-Jumah & Saud Alarifi. (2020) Exploration of Cadmium Dioxide Nanoparticles on Bioaccumulation, Oxidative Stress, and Carcinogenic Potential in Oreochromis mossambicus L. . Oxidative Medicine and Cellular Longevity 2020, pages 1-11.
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Diego J. Nogueira, Miriam Arl, Jéssica S. Köerich, Carmen Simioni, Luciane C. Ouriques, Denice S. Vicentini & William G. Matias. (2019) Comparison of cytotoxicity of α-Al2O3 and η-Al2O3 nanoparticles toward neuronal and bronchial cells. Toxicology in Vitro 61, pages 104596.
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Mengling Li, Zheng‐guo Cui, Shahbaz Ahmad Zakki, Qianwen Feng, Lu Sun, Loreto B. FerilJrJr & Hidekuni Inadera. (2019) Aluminum chloride causes 5‐fluorouracil resistance in hepatocellular carcinoma HepG2 cells. Journal of Cellular Physiology 234:11, pages 20249-20265.
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Eliana Baez-Jurado, Gina Guio-Vega, Oscar Hidalgo-Lanussa, Janneth González, Valentina Echeverria, Ghulam Md Ashraf, Amirhossein Sahebkar & George E. Barreto. (2018) Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury. Molecular Neurobiology 56:7, pages 5167-5187.
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Saud Alarifi, Daoud Ali & Saad Alkahtani. (2017) Oxidative Stress-Induced DNA Damage by Manganese Dioxide Nanoparticles in Human Neuronal Cells. BioMed Research International 2017, pages 1-10.
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