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Review

Multifaceted applications of bile salts in pharmacy: an emphasis on nanomedicine

Pages 3955-3971 | Published online: 12 Jun 2015

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Sara M. Soliman, Shaimaa Mosallam, Mohamed A. Mamdouh, Mohammed Abdalla Hussein & Shady M. Abd El-Halim. (2022) Design and optimization of cranberry extract loaded bile salt augmented liposomes for targeting of MCP-1/STAT3/VEGF signaling pathway in DMN-intoxicated liver in rats. Drug Delivery 29:1, pages 427-439.
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Marija Gvoic, Sasa Vukmirovic, Hani Al-Salami, Armin Mooranian, Momir Mikov & Karmen Stankov. (2021) Bile acids as novel enhancers of CNS targeting antitumor drugs: a comprehensive review. Pharmaceutical Development and Technology 26:6, pages 617-633.
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Mohamed Ahmed El-Nabarawi, Rehab Nabil Shamma, Faten Farouk & Samar Mohamed Nasralla. (2020) Bilosomes as a novel carrier for the cutaneous delivery for dapsone as a potential treatment of acne: preparation, characterization and in vivo skin deposition assay. Journal of Liposome Research 30:1, pages 1-11.
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Poonam Parashar, Preeti Rana, Monika Dwivedi & Shubhini A Saraf. (2019) Dextrose modified bilosomes for peroral delivery: improved therapeutic potential and stability of silymarin in diethylnitrosamine-induced hepatic carcinoma in rats. Journal of Liposome Research 29:3, pages 251-263.
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Rajan Rajabalaya, Muhammad Nuh Musa, Nurolaini Kifli & Sheba R David. (2017) Oral and transdermal drug delivery systems: role of lipid-based lyotropic liquid crystals. Drug Design, Development and Therapy 11, pages 393-406.
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Célia Faustino, Cláudia Serafim, Patrícia Rijo & Catarina Pinto Reis. (2016) Bile acids and bile acid derivatives: use in drug delivery systems and as therapeutic agents. Expert Opinion on Drug Delivery 13:8, pages 1133-1148.
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Subhrajit Mohanty, Binita Tirkey, Soumya Ranjan Jena, Luna Samanta & Usharani Subuddhi. (2023) Exploring Steroidal Surfactants as Potential Drug Carriers for an Anticancer Drug Curcumin: An Insight into the Effect of Surfactants’ Structure on the Photophysical Properties, Stability, and Activity of Curcumin. Langmuir 39:5, pages 1852-1869.
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Claudia Pigliacelli, Peter Belton, Peter Wilde, Francesca Baldelli Bombelli, Paul A. Kroon, Mark S. Winterbone & Sheng Qi. (2023) Interaction of polymers with bile salts – Impact on solubilisation and absorption of poorly water-soluble drugs. Colloids and Surfaces B: Biointerfaces 222, pages 113044.
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Paresh Y. Parekh, Vijay I. Patel, Mehul R. Khimani & Pratap Bahadur. (2023) Self-assembly of bile salts and their mixed aggregates as building blocks for smart aggregates. Advances in Colloid and Interface Science 312, pages 102846.
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Ana ToaderMariaMaria, Izabella Dascalu, Elena NeacsuIonelaIonela & Mirela Enache. (2023) Binding interactions of actinomycin D anticancer drug with bile salts micelles. Journal of the Serbian Chemical Society 88:4, pages 367-379.
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Raghda Abdel-moneum & Rania S. Abdel-Rashid. (2023) Bile salt stabilized nanovesicles as a promising drug delivery technology: A general overview and future perspectives. Journal of Drug Delivery Science and Technology 79, pages 104057.
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Mariam Zewail, Passent M. E. Gaafar, Nancy Abdel Hamid Abou Youssef, Merhan E. Ali, Mai F. Ragab, Miranda F. Kamal, Mohamed H. Noureldin & Haidy Abbas. (2022) Novel Siprulina platensis Bilosomes for Combating UVB Induced Skin Damage. Pharmaceuticals 16:1, pages 36.
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Mutasem Rawas-Qalaji, Hnin Ei Thu & Zahid Hussain. (2022) Oromucosal delivery of macromolecules: Challenges and recent developments to improve bioavailability. Journal of Controlled Release 352, pages 726-746.
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Mohadeseh Nemati, Anahita Fathi‐Azarbayjani, Hani Al‐Salami, Elmira Roshani Asl & Yousef Rasmi. (2022) Bile acid‐based advanced drug delivery systems, bilosomes and micelles as novel carriers for therapeutics. Cell Biochemistry and Function 40:6, pages 623-635.
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Daisuke Watase, Shuichi Setoguchi, Nami Nagata-Akaho, Shotaro Goto, Hirofumi Yamakawa, Ayano Yamada, Mitsuhisa Koga, Yoshiharu Karube, Kazuhisa Matsunaga & Jiro Takata. (2022) Cationic N,N-Dimethylglycine Ester Prodrug of 2R-α-Tocotrienol Promotes Intestinal Absorption via Efficient Self-Micellization with Intrinsic Bile Acid Anion. Molecules 27:9, pages 2727.
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Manal A. Elsheikh, Yasmin A. El-Feky, Majid Mohammad Al-Sawahli, Merhan E. Ali, Ahmed M. Fayez & Haidy Abbas. (2022) A Brain-Targeted Approach to Ameliorate Memory Disorders in a Sporadic Alzheimer’s Disease Mouse Model via Intranasal Luteolin-Loaded Nanobilosomes. Pharmaceutics 14:3, pages 576.
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Haidy Abbas, Nesrine S. El Sayed, Merhan E. Ali & Manal A. Elsheikh. (2022) Integrated lecithin–bile salt nanovesicles as a promising approach for effective skin delivery of luteolin to improve UV-induced skin damage in Wistar Albino rats. Colloids and Surfaces B: Biointerfaces 211, pages 112299.
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Ameeduzzafar Zafar, Nabil K Alruwaili, Syed Sarim Imam, Mohd Yasir, Omar Awad Alsaidan, Ali Alquraini, Alenazy Rawaf, Bader Alsuwayt, Md. Khalid Anwer, Sultan Alshehri & Mohammed M. Ghoneim. (2022) Development and Optimization of Nanolipid-Based Formulation of Diclofenac Sodium: In Vitro Characterization and Preclinical Evaluation. Pharmaceutics 14:3, pages 507.
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Aygul Can, Arwen I.I. Tyler & Alan R. Mackie. (2021) Potential use of bile salts in lipid self-assembled systems for the delivery of phytochemicals. Current Opinion in Colloid & Interface Science 56, pages 101502.
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Subinur Ilshat Kemal, Camila Alexandra Uribe Ortiz & Vivek Sharma. (2021) Surface forces and stratification in foam films formed with bile salts. Molecular Systems Design & Engineering 6:7, pages 520-533.
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Yashwant Kumar, Reena Yadav & Alka Bhatia. (2020) Can natural detergent properties of bile acids be used beneficially in tackling coronavirus disease-19?. Future Virology 15:12, pages 779-782.
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Lamiaa R. Abdelalim, Ossama Y. Abdallah & Yosra S.R. Elnaggar. (2020) High efficacy, rapid onset nanobiolosomes of sildenafil as a topical therapy for erectile dysfunction in aged rats. International Journal of Pharmaceutics 591, pages 119978.
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Zoya Saifi, Md. Rizwanullah, Showkat R. Mir & Saima Amin. (2020) Bilosomes nanocarriers for improved oral bioavailability of acyclovir: A complete characterization through in vitro, ex-vivo and in vivo assessment. Journal of Drug Delivery Science and Technology 57, pages 101634.
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S. Kecman, R. Škrbić, Alma Badnjevic Cengic, A. Mooranian, H. Al-Salami, M. Mikov & S. Golocorbin-Kon. (2020) Potentials of human bile acids and their salts in pharmaceutical nano delivery and formulations adjuvants. Technology and Health Care 28:3, pages 325-335.
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Mennatullah M. Ibrahim, Emad B. Basalious & Mohamed A. El-Nabarawi. (2020) Consolidated bile-based vesicles/self-nanoemulsifying system (CBBVs/SNES) as a solution for limitations of oral delivery of vesicular dispersions: In-vitro optimization and elucidation of ex-vivo intestinal transport mechanisms. Journal of Drug Delivery Science and Technology 56, pages 101489.
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