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International Journal of Nanomedicine Volume 10, 2015 - Issue
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Original Research

Codelivery of SH-aspirin and curcumin by mPEG-PLGA nanoparticles enhanced antitumor activity by inducing mitochondrial apoptosis

Lin Zhou1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China;2 Sichuan Food and Drug Safety Monitoring and Review of Certification, Adverse Reaction Monitoring Center, Drug Abuse Monitoring Center, Chengdu, People’s Republic of China
,
Xingmei Duan1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China;2 Sichuan Food and Drug Safety Monitoring and Review of Certification, Adverse Reaction Monitoring Center, Drug Abuse Monitoring Center, Chengdu, People’s Republic of China
,
Shi Zeng1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China
,
Ke Men1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China
,
Xueyan Zhang1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of China
,
Li Yang1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of ChinaCorrespondence[email protected]
&
Xiang Li1 State Key Laboratory of Biotherapy, Cancer Center and Department of Urology, West China Hospital, Sichuan University, Chengdu, People’s Republic of ChinaCorrespondence[email protected]
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Pages 5205-5218 | Published online: 18 Aug 2015

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Yingli Wu, Yu Yang, Xiaolin Lv, Menghan Gao, Xujin Gong, Qingqiang Yao & Yanna Liu. (2023) Nanoparticle-Based Combination Therapy for Ovarian Cancer. International Journal of Nanomedicine 18, pages 1965-1987.
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Intouch Sakpakdeejaroen, Sukrut Somani, Margaret Mullin & Christine Dufès. (2020) Development of transferrin-bearing vesicles encapsulating aspirin for cancer therapy. Journal of Liposome Research 30:2, pages 174-181.
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Ming Shao, Weitao Zhu, Xianping Lv, Qiankun Yang, Xin Liu, Ying Xie, Ping Tang & Ling Sun. (2018) Encapsulation of chloroquine and doxorubicin by MPEG-PLA to enhance anticancer effects by lysosomes inhibition in ovarian cancer. International Journal of Nanomedicine 13, pages 8231-8245.
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Maryam Afsharzadeh, Maryam Hashemi, Ahad Mokhtarzadeh, Khalil Abnous & Mohammad Ramezani. (2018) Recent advances in co-delivery systems based on polymeric nanoparticle for cancer treatment. Artificial Cells, Nanomedicine, and Biotechnology 46:6, pages 1095-1110.
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Yinghua Li, Zhengfang Lin, Mingqi Zhao, Tiantian Xu, Changbing Wang, Huimin Xia, Hanzhong Wang & Bing Zhu. (2016) Multifunctional selenium nanoparticles as carriers of HSP70 siRNA to induce apoptosis of HepG2 cells. International Journal of Nanomedicine 11, pages 3065-3076.
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Phuong H.L. Tran, Beom-Jin Lee & Thao T.D. Tran. (2021) Current Studies of Aspirin as an Anticancer Agent and Strategies to Strengthen its Therapeutic Application in Cancer. Current Pharmaceutical Design 27:18, pages 2209-2220.
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Nanasaheb D. Thorat, Ewa Dworniczek, Grace Brennan, Grzegorz Chodaczek, Rabah Mouras, Victoria Gascón Pérez, Christophe Silien, Syed A. M. Tofail & Joanna Bauer. (2021) Photo-responsive functional gold nanocapsules for inactivation of community-acquired, highly virulent, multidrug-resistant MRSA. Journal of Materials Chemistry B 9:3, pages 846-856.
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Nadia G. Kandile, Hemat M. Mohamed & Abir S. Nasr. (2020) Novel hydrazinocurcumin derivative loaded chitosan, ZnO, and Au nanoparticles formulations for drug release and cell cytotoxicity. International Journal of Biological Macromolecules 158, pages 1216-1226.
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Peng He, Hong Yan, Junning Zhao, Maling Gou & Xiaolu Li. (2019) An evaluation of the wound healing potential of tetrahydrocurcumin-loaded MPEG-PLA nanoparticles. Journal of Biomaterials Applications 34:3, pages 315-325.
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R. López-Muñoz, M. E. Treviño, G. Morales, J. A. Valdez-Garza, R. Díaz de León, H. Saade, F. J. Enríquez-Medrano & R. G. López. (2019) Ultrafine Nanoparticles of Poly(Methyl Methacrylate- co -Methacrylic Acid) Loaded with Aspirin . Journal of Nanomaterials 2019, pages 1-9.
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Tanweer Haider, Rahul Tiwari, Suresh Prasad Vyas & Vandana Soni. (2019) Molecular determinants as therapeutic targets in cancer chemotherapy: An update. Pharmacology & Therapeutics 200, pages 85-109.
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Kamil Rahme & Nazih Dagher. (2019) Chemistry Routes for Copolymer Synthesis Containing PEG for Targeting, Imaging, and Drug Delivery Purposes. Pharmaceutics 11:7, pages 327.
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Donato Cosco, Rosario Mare, Donatella Paolino, Maria Cristina Salvatici, Felisa Cilurzo & Massimo Fresta. (2019) Sclareol-loaded hyaluronan-coated PLGA nanoparticles: Physico-chemical properties and in vitro anticancer features. International Journal of Biological Macromolecules 132, pages 550-557.
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Yinghua Li, Tiantian Xu, Zhengfang Lin, Changbing Wang, Yu Xia, Min Guo, Mingqi Zhao, Yi Chen & Bing Zhu. (2019) Inhibition of Enterovirus A71 by Selenium Nanoparticles Interferes with JNK Signaling Pathways. ACS Omega 4:4, pages 6720-6725.
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Mohammad Sajid, Swaranjit Singh Cameotra, Mohd Sajjad Ahmad Khan & Iqbal Ahmad. 2019. New Look to Phytomedicine. New Look to Phytomedicine 597 623 .
Giovanna Lollo, Gabriela Ullio-Gamboa, Edmundo Fuentes, Kevin Matha, Nolwenn Lautram & Jean-Pierre Benoit. (2018) In vitro anti-cancer activity and pharmacokinetic evaluation of curcumin-loaded lipid nanocapsules. Materials Science and Engineering: C 91, pages 859-867.
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Mahboubeh Ebrahimian, Sahar Taghavi, Ahad Mokhtarzadeh, Mohammad Ramezani & Maryam Hashemi. (2017) Co-delivery of Doxorubicin Encapsulated PLGA Nanoparticles and Bcl-xL shRNA Using Alkyl-Modified PEI into Breast Cancer Cells. Applied Biochemistry and Biotechnology 183:1, pages 126-136.
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Lipika Ray, Manish Kumar Pal & Ratan Singh Ray. (2017) Synergism of co-delivered nanosized antioxidants displayed enhanced anticancer efficacy in human colon cancer cell lines. Bioactive Materials 2:2, pages 82-95.
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Yinghua Li, Zhengfang Lin, Tiantian Xu, Changbing Wang, Mingqi Zhao, Misi Xiao, Hanzhong Wang, Ning Deng & Bing Zhu. (2017) Delivery of VP1 siRNA to inhibit the EV71 virus using functionalized silver nanoparticles through ROS-mediated signaling pathways. RSC Advances 7:3, pages 1453-1463.
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Divya Arora & Sundeep Jaglan. (2016) Nanocarriers based delivery of nutraceuticals for cancer prevention and treatment: A review of recent research developments. Trends in Food Science & Technology 54, pages 114-126.
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Yinbo Zhao, Qi Zeng, Fengbo Wu, Jing Li, Zhaoping Pan, Pengfei Shen, Lu Yang, Ting Xu, Lulu Cai & Li Guo. (2016) Novel naproxen-peptide-conjugated amphiphilic dendrimer self-assembly micelles for targeting drug delivery to osteosarcoma cells. RSC Advances 6:65, pages 60327-60335.
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