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Original Research

Novel piperine-loaded Tween-integrated monoolein cubosomes as brain-targeted oral nanomedicine in Alzheimer’s disease: pharmaceutical, biological, and toxicological studies

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Pages 5459-5473 | Published online: 27 Aug 2015

Keep up to date with the latest research on this topic with citation updates for this article.

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Ajit Singh, Debarati Rakshit, Ankit Kumar, Awanish Mishra & Rahul Shukla. (2023) Vitamin E modified polyamidoamine dendrimer for piperine delivery to alleviate Aβ1–42 induced neurotoxicity in Balb/c mice model. Journal of Biomaterials Science, Polymer Edition 34:16, pages 2232-2254.
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Amira Mohamed Mohsen, Abeer A. A. Salama & Marwa Hasanein Asfour. (2023) Cubosome-based thermosensitive in situ gelling system for intranasal administration of lamotrigine with enhanced antiepileptic efficacy. Pharmaceutical Development and Technology 28:6, pages 520-534.
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Ajit Singh, Rewati R. Ujjwal, Saba Naqvi, Rahul K. Verma, Sanjay Tiwari, Prashant Kesharwani & Rahul Shukla. (2022) Formulation development of tocopherol polyethylene glycol nanoengineered polyamidoamine dendrimer for neuroprotection and treatment of Alzheimer disease. Journal of Drug Targeting 30:7, pages 777-791.
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Sayan Biswas, Pulok K. Mukherjee, Amit Kar, Subhadip Bannerjee, Rawiwan Charoensub & Thidarat Duangyod. (2021) Optimized piperine–phospholipid complex with enhanced bioavailability and hepatoprotective activity. Pharmaceutical Development and Technology 26:1, pages 69-80.
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Heshu Sulaiman Rahman, Hemn Hassan Othman, Nahidah Ibrahim Hammadi, Swee Keong Yeap, Kawa Mohammad Amin, Nozlena Abdul Samad & Noorjahan Banu Alitheen. (2020) Novel Drug Delivery Systems for Loading of Natural Plant Extracts and Their Biomedical Applications. International Journal of Nanomedicine 15, pages 2439-2483.
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Cang Huynh Mai, Tung Thanh Diep, Thuy T. T. Le & Viet Nguyen. (2020) Advances in colloidal dispersions: A review. Journal of Dispersion Science and Technology 41:4, pages 479-494.
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Tianjing Ren & Zhong Zuo. (2019) Role of piperine in CNS diseases: pharmacodynamics, pharmacokinetics and drug interactions. Expert Opinion on Drug Metabolism & Toxicology 15:10, pages 849-867.
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Mohamed Yasser, Mahmoud Teaima, Mohamed El-Nabarawi & Rehab Abd El-Monem. (2019) Cubosomal based oral tablet for controlled drug delivery of telmisartan: formulation, in-vitro evaluation and in-vivo comparative pharmacokinetic study in rabbits. Drug Development and Industrial Pharmacy 45:6, pages 981-994.
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Shaimaa El-Housiny, Maii Atef Shams Eldeen, Yasmina Ahmed El-Attar, Hoda A. Salem, Dalia Attia, Ehab R. Bendas & Mohamed A. El-Nabarawi. (2018) Fluconazole-loaded solid lipid nanoparticles topical gel for treatment of pityriasis versicolor: formulation and clinical study. Drug Delivery 25:1, pages 78-90.
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Guangtao Xu, Huan Gu, Bo Hu, Fei Tong, Daojun Liu, Xiaojun Yu, Yongxia Zheng & Jiang Gu. (2017) PEG-b-(PELG-g-PLL) nanoparticles as TNF-α nanocarriers: potential cerebral ischemia/reperfusion injury therapeutic applications. International Journal of Nanomedicine 12, pages 2243-2254.
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Yosra SR Elnaggar, Sara M Talaat, Mohammed Bahey-El-Din & Ossama Y Abdallah. (2016) Novel lecithin-integrated liquid crystalline nanogels for enhanced cutaneous targeting of terconazole: development, in vitro and in vivo studies. International Journal of Nanomedicine 11, pages 5531-5547.
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May S Freag, Yosra SR Elnaggar, Doaa A Abdelmonsif & Ossama Y Abdallah. (2016) Stealth, biocompatible monoolein-based lyotropic liquid crystalline nanoparticles for enhanced aloe-emodin delivery to breast cancer cells: in vitro and in vivo studies. International Journal of Nanomedicine 11, pages 4799-4818.
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Ayesha Waheed & Mohd. Aqil. (2021) Lyotropic liquid crystalline nanoparticles: Scaffolds for delivery of myriad therapeutics and diagnostics. Journal of Molecular Liquids 338, pages 116919.
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Crossref
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Jiali Zhai, Celesta Fong, Nhiem Tran & Calum J. Drummond. (2019) Non-Lamellar Lyotropic Liquid Crystalline Lipid Nanoparticles for the Next Generation of Nanomedicine. ACS Nano 13:6, pages 6178-6206.
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Stephanie Andrade, Maria João Ramalho, Joana Angélica Loureiro & Maria do Carmo Pereira. (2019) Natural Compounds for Alzheimer’s Disease Therapy: A Systematic Review of Preclinical and Clinical Studies. International Journal of Molecular Sciences 20:9, pages 2313.
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Hanna M. G. Barriga, Margaret N. Holme & Molly M. Stevens. (2019) Cubosomes: The Next Generation of Smart Lipid Nanoparticles?. Angewandte Chemie International Edition 58:10, pages 2958-2978.
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Hanna M. G. Barriga, Margaret N. Holme & Molly M. Stevens. (2018) Cubosomen: die nächste Generation intelligenter Lipid‐Nanopartikel?. Angewandte Chemie 131:10, pages 2984-3006.
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Filippo Valente, Helena Bysell, Edi Simoni, Lukas Boge, Mimmi Eriksson, Alessandro Martini & Laura Astolfi. (2018) Evaluation of toxicity of glycerol monooleate nanoparticles on PC12 cell line. International Journal of Pharmaceutics 539:1-2, pages 23-30.
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Mona A. Moustafa, Yosra S.R. Elnaggar, Wessam M. El-Refaie & Ossama Y. Abdallah. (2017) Hyalugel-integrated liposomes as a novel ocular nanosized delivery system of fluconazole with promising prolonged effect. International Journal of Pharmaceutics 534:1-2, pages 14-24.
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Yosra SR Elnaggar, Eman MM Shehata, Sally Galal & Ossama Y Abdallah. (2017) Self-emulsifying preconcentrates of daidzein–phospholipid complex: design, in vitro and in vivo appraisal . Nanomedicine 12:8, pages 893-910.
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Chad Curtis, Mengying Zhang, Rick Liao, Thomas Wood & Elizabeth Nance. (2016) Systems‐level thinking for nanoparticle‐mediated therapeutic delivery to neurological diseases. WIREs Nanomedicine and Nanobiotechnology 9:2.
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Francesco Bonetti, Gloria Brombo & Giovanni Zuliani. 2017. Nutrition and Functional Foods for Healthy Aging. Nutrition and Functional Foods for Healthy Aging 211 232 .
May S Freag, Yosra SR Elnaggar, Doaa A Abdelmonsif & Ossama Y Abdallah. (2016) Layer-by-layer-coated lyotropic liquid crystalline nanoparticles for active tumor targeting of rapamycin. Nanomedicine 11:22, pages 2975-2996.
Crossref
Mohammad Younus, Richard N. Prentice, Andrew N. Clarkson, Ben J. Boyd & Shakila B. Rizwan. (2016) Incorporation of an Endogenous Neuromodulatory Lipid, Oleoylethanolamide, into Cubosomes: Nanostructural Characterization. Langmuir 32:35, pages 8942-8950.
Crossref
Zahra Karami & Mehrdad Hamidi. (2016) Cubosomes: remarkable drug delivery potential. Drug Discovery Today 21:5, pages 789-801.
Crossref