Combination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects

Yin-Chih Fu1 Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan;2 Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan;3 Department of Orthopaedics, Kaohsiung Medical University, Kaohsiung, Taiwan;4 Department of Orthopaedics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Yan-Hsiung Wang1 Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan;5 School of Dentistry, College of Dental Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Chung-Hwan Chen1 Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan;3 Department of Orthopaedics, Kaohsiung Medical University, Kaohsiung, Taiwan;4 Department of Orthopaedics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Chih-Kuang Wang1 Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan;6 Department of Medicinal and Applied Chemistry, Kaohsiung Medical University, Kaohsiung, Taiwan

Gwo-Jaw Wang1 Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan;3 Department of Orthopaedics, Kaohsiung Medical University, Kaohsiung, Taiwan;4 Department of Orthopaedics, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan

Mei-Ling Ho1 Orthopaedic Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan;3 Department of Orthopaedics, Kaohsiung Medical University, Kaohsiung, Taiwan;7 Department of Physiology, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan;8 Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung, TaiwanCorrespondence[email protected]

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Combination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects

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Combination of calcium sulfate and simvastatin-controlled release microspheres enhances bone repair in critical-sized rat calvarial bone defects

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