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International Medical Case Reports Journal Volume 8, 2015 - Issue
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Case Report

Synergistic effect of regenerating agent plus cord blood serum eye drops for the treatment of resistant neurotrophic keratitis: a case report and a hypothesis for pathophysiologic mechanism

Giuseppe Giannaccare1 Ophthalmology Unit, DIMES, S Orsola-Malpighi Teaching Hospital, University of Bologna, Bologna, ItalyCorrespondence[email protected]
,
Michela Fresina1 Ophthalmology Unit, DIMES, S Orsola-Malpighi Teaching Hospital, University of Bologna, Bologna, Italy
,
Aldo Vagge2 Eye Clinic, DiNOGMI, University of Genoa, Genoa, Italy
&
Piera Versura1 Ophthalmology Unit, DIMES, S Orsola-Malpighi Teaching Hospital, University of Bologna, Bologna, Italy
Pages 277-281 | Published online: 02 Nov 2015

Citations (17)

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Read on this site (2)

Giuseppe Giannaccare, Marco Pellegrini, Federico Bolognesi, Paolo Fogagnolo, Enrico Lupardi, Fabiana Allevi, Federico Bernabei, Alessandro Lozza, Christian Plazza, Claudio Marchetti, Vincenzo Scorcia & Federico Biglioli. (2021) Spotlight on corneal neurotization. Expert Review of Ophthalmology 16:3, pages 175-184.
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Piera Versura, Giuseppe Giannaccare, Marco Pellegrini, Stefano Sebastiani & Emilio C Campos. (2018) Neurotrophic keratitis: current challenges and future prospects. Eye and Brain 10, pages 37-45.
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Articles from other publishers (15)

E. A. Kasparova & N. R. Marchenko. (2022) Neurotrophic Keratitis. Etiology, Pathogenesis, Clinical Manifestations. Review. Part 2. Ophthalmology in Russia 19:2, pages 265-271.
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Deanna H. Dang, Kamran M. Riaz & Dimitrios Karamichos. (2022) Treatment of Non-Infectious Corneal Injury: Review of Diagnostic Agents, Therapeutic Medications, and Future Targets. Drugs 82:2, pages 145-167.
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Koray Gumus. (2021) On the Horizon: Biologics and Nutrients for Neurotrophic Keratitis. Eye & Contact Lens: Science & Clinical Practice 47:3, pages 154-156.
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Paolo Fogagnolo, Giuseppe Giannaccare, Federico Bolognesi, Maurizio Digiuni, Laura Tranchina, Luca Rossetti, Angelica Dipinto, Fabiana Allevi, Alessandro Lozza, Dimitri Rabbiosi, Silvia Mariani, Marco Pellegrini, Federica E. Cazzola, Simone Bagaglia, Cosimo Mazzotta, Guido Gabriele, Paolo Gennaro, Giovanni Badiali, Claudio Marchetti, Emilio C. Campos & Federico Biglioli. (2020) Direct Versus Indirect Corneal Neurotization for the Treatment of Neurotrophic Keratopathy. American Journal of Ophthalmology 220, pages 203-214.
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Tolga Kocatürk, Mustafa Alemdar, Özge Key, Harun Çakmak & José L. Güell. (2020) Matrix regenerating agent (RGTA) plays a prominent role in treating persistent epithelial defects. Journal of EuCornea 7, pages 17-22.
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Giuseppe Giannaccare, Adriano Carnevali, Carlotta Senni, Laura Logozzo & Vincenzo Scorcia. (2020) Umbilical Cord Blood and Serum for the Treatment of Ocular Diseases: A Comprehensive Review. Ophthalmology and Therapy 9:2, pages 235-248.
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F. Pérez-Bartolomé, D. Mingo Botín, E. de Dompablo, P. de Arriba, F. Arnalich Montiel & F.J. Muñoz Negrete. (2019) Post-herpes neurotrophic keratopathy: Aetiopathogenesis, clinical signs and current therapies. Archivos de la Sociedad Española de Oftalmología (English Edition) 94:4, pages 171-183.
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F. Pérez-Bartolomé, D. Mingo Botín, E. de Dompablo, P. de Arriba, F. Arnalich Montiel & F.J. Muñoz Negrete. (2019) Queratopatía neurotrófica postherpética: etiopatogenia, clínica y terapias actuales. Archivos de la Sociedad Española de Oftalmología 94:4, pages 171-183.
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Paolo Rebulla, Sergi Querol & Alejandro Madrigal. 2019. Perinatal Stem Cells. Perinatal Stem Cells 75 82 .
Nader Nassiri, Farhad Assarzadegan, Mansoor Shahriari, Hamid Norouzi, Sara Kavousnezhad, Nariman Nassiri & Kourosh Sheibani. (2018) Vitamin B12 Deficiency as a Cause of Neurotrophic Keratopathy. The Open Ophthalmology Journal 12:1, pages 7-11.
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Mohammed Ziaei, Carol Greene & Colin R. Green. (2018) Wound healing in the eye: Therapeutic prospects. Advanced Drug Delivery Reviews 126, pages 162-176.
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Olena Pogozhykh, Volodymyr Prokopyuk, Constança Figueiredo & Denys Pogozhykh. (2018) Placenta and Placental Derivatives in Regenerative Therapies: Experimental Studies, History, and Prospects. Stem Cells International 2018, pages 1-14.
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Mina Rizk, Joseph Aziz, Risa Shorr & David S. Allan. (2017) Cell-Based Therapy Using Umbilical Cord Blood for Novel Indications in Regenerative Therapy and Immune Modulation: An Updated Systematic Scoping Review of the Literature. Biology of Blood and Marrow Transplantation 23:10, pages 1607-1613.
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Giuseppe Giannaccare, Piera Versura, Marina Buzzi, Laura Primavera, Marco Pellegrini & Emilio C. Campos. (2017) Blood derived eye drops for the treatment of cornea and ocular surface diseases. Transfusion and Apheresis Science 56:4, pages 595-604.
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Marta Sacchetti & Alessandro Lambiase. (2017) Neurotrophic factors and corneal nerve regeneration. Neural Regeneration Research 12:8, pages 1220.
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