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Journal of Asthma and Allergy Volume 9, 2016 - Issue

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Original Research

Anti-inflammatory dosing of theophylline in the treatment of status asthmaticus in children

Nemr S Eid1 Division of Pediatric Pulmonology, University of LouisvilleCorrespondence[email protected]

Adrian O’Hagan1 Division of Pediatric Pulmonology, University of Louisville

Scott Bickel1 Division of Pediatric Pulmonology, University of Louisville

Ronald Morton1 Division of Pediatric Pulmonology, University of Louisville

Sarah Jacobson2 Department of Pharmacy, Kosair Children’s Hospital

John A Myers3 Department of Pediatrics, University of Louisville, Louisville, KY, USA

Pages 183-189 | Published online: 13 Oct 2016

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Katarzyna Wójcik-Pszczoła, Krzysztof Pociecha, Grażyna Chłoń-Rzepa, Monika Zadrożna, Barbara Nowak, Hanna Plutecka, Paulina Koczurkiewicz-Adamczyk, Katarzyna Przejczowska-Pomierny, Elżbieta Pękala, Reinoud Gosens & Elżbieta Wyska. (2023) Inhaled pan-phosphodiesterase inhibitors ameliorate ovalbumin-induced airway inflammation and remodeling in murine model of allergic asthma. International Immunopharmacology 119, pages 110264.
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Dirk Tänzler, Marc Kipping, Marcell Lederer, Wiebke F. Günther, Christian Arlt, Stefan Hüttelmaier, Andreas Merkenschlager & Andrea Sinz. (2023) Effects of theophylline on ADCY5 activation—From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients. PLOS ONE 18:3, pages e0282593.
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Katarzyna Wójcik-Pszczoła, Agnieszka Jankowska, Marietta Ślusarczyk, Bogdan Jakieła, Hanna Plutecka, Krzysztof Pociecha, Artur Świerczek, Justyna Popiół, Paulina Koczurkiewicz-Adamczyk, Elżbieta Wyska, Elżbieta Pękala, Reinoud Gosens & Grażyna Chłoń-Rzepa. (2021) Synthesis and in vitro evaluation of anti-inflammatory, antioxidant, and anti-fibrotic effects of new 8-aminopurine-2,6-dione-based phosphodiesterase inhibitors as promising anti-asthmatic agents. Bioorganic Chemistry 117, pages 105409.
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A. Aralihond, Z. Shanta, A. Pullattayil & C.V.E. Powell. (2021) Treating acute severe asthma attacks in children: using aminophylline. Breathe 16:4, pages 200081.
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Ying Zhang, Ran Guo, Guo-xin Li, Xiao-feng Ling, Isao Noda & Yizhuang Xu. (2020) Investigation on the interaction between theophylline and alkaline substances using the DAOSD approach. Journal of Molecular Structure 1202, pages 127294.
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Alejandro E. Gutierrez, Prachi Shah, Abigail E. Rex, Tien C. Nguyen, Saamiha P. Kenkare, Jeffrey E. Barrick & Dennis M. Mishler. (2019) Bioassay for Determining the Concentrations of Caffeine and Individual Methylxanthines in Complex Samples. Applied and Environmental Microbiology 85:23.
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Pankaj Bhavsar, Georgina Harmer, Ian M. Adcock & Kian Fan Chung. 2019. Severe Asthma. Severe Asthma 211 230 .

Luciana Indinnimeo, Elena Chiappini & Michele Miraglia del Giudice. (2018) Guideline on management of the acute asthma attack in children by Italian Society of Pediatrics. Italian Journal of Pediatrics 44:1.
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Sheng-Chieh Lin, Fang-Yi Cheng, Jun-Jen Liu & Yi-Ling Ye. (2018) Expression and Regulation of Thymic Stromal Lymphopoietin and Thymic Stromal Lymphopoietin Receptor Heterocomplex in the Innate–Adaptive Immunity of Pediatric Asthma. International Journal of Molecular Sciences 19:4, pages 1231.
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Erin K. Stenson, Michael J. Tchou & Derek S. Wheeler. (2017) Management of acute asthma exacerbations. Current Opinion in Pediatrics 29:3, pages 305-310.
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Anti-inflammatory dosing of theophylline in the treatment of status asthmaticus in children

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Anti-inflammatory dosing of theophylline in the treatment of status asthmaticus in children

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