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Journal of Asthma and Allergy Volume 14, 2021 - Issue
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Original Research

Tezepelumab Reduces Exacerbations Across All Seasons in Patients with Severe, Uncontrolled Asthma: A Post Hoc Analysis of the PATHWAY Phase 2b Study

Jonathan Corren1 Departments of Medicine and Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, CA, USACorrespondence[email protected]
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,
Martin Karpefors2 Data Science and AI, AstraZeneca, Gothenburg, SwedenORCID Iconhttps://orcid.org/0000-0003-3136-9882View further author information
ORCID Icon,
Åsa Hellqvist3 Biometrics, Late-Stage Development, Respiratory and Immunology, AstraZeneca, Gothenburg, SwedenView further author information
,
Jane R Parnes4 Amgen, Thousand Oaks, CA, USAView further author information
&
Gene Colice5 Late-Stage Development, Respiratory and Immunology, AstraZeneca, Gaithersburg, MD, USAView further author information
Pages 1-11 | Published online: 11 Jan 2021

Citations (16)

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Jane R Parnes, Nestor A Molfino, Gene Colice, Ubaldo Martin, Jonathan Corren & Andrew Menzies-Gow. (2022) Targeting TSLP in Asthma. Journal of Asthma and Allergy 15, pages 749-765.
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Articles from other publishers (15)

William C. AndersonIIIIII, Tina M. Banzon, Bo Chawes, Nikolaos G. Papadopoulos, Wanda Phipatanakul & Stanley J. Szefler. (2023) Factors to Consider in Prescribing Asthma Biologic Therapies to Children. The Journal of Allergy and Clinical Immunology: In Practice 11:3, pages 693-701.
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Gail M. Gauvreau, Celine Bergeron, Louis‐Philippe Boulet, Donald W. Cockcroft, Andréanne Côté, Beth E. Davis, Richard Leigh, Irvin Myers, Paul M. O'Byrne & Roma Sehmi. (2022) Sounding the alarmins—The role of alarmin cytokines in asthma. Allergy 78:2, pages 402-417.
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Momoko Kurihara, Hiroki Kabata, Misato Irie & Koichi Fukunaga. (2023) Current summary of clinical studies on anti-TSLP antibody, Tezepelumab, in asthma. Allergology International 72:1, pages 24-30.
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Grzegorz Kardas, Michał Panek, Piotr Kuna, Piotr Damiański & Maciej Kupczyk. (2022) Monoclonal antibodies in the management of asthma: Dead ends, current status and future perspectives. Frontiers in Immunology 13.
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Donya Imanirad & Farnaz Tabatabaian. (2022) Current Biologics in Asthma Treatment. Seminars in Respiratory and Critical Care Medicine 43:05, pages 627-634.
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Elizabeth Chorvinsky, Gustavo Nino, Kyle Salka, Susana Gaviria, Maria J. Gutierrez & Dinesh K. Pillai. (2022) TSLP bronchoalveolar lavage levels at baseline are linked to clinical disease severity and reduced lung function in children with asthma. Frontiers in Pediatrics 10.
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Samuel Cerps, Asger Sverrild, Sangeetha Ramu, Juan José Nieto‐Fontarigo, Hamid Akbarshahi, Mandy Menzel, Cecilia Andersson, Sofia Tillgren, Morten Hvidtfeldt, Celeste Porsbjerg & Lena Uller. (2022) House dust mite sensitization and exposure affects bronchial epithelial anti‐microbial response to viral stimuli in patients with asthma. Allergy 77:8, pages 2498-2508.
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Martin Steinhoff, Fareed Ahmad, Atul Pandey, Angeliki Datsi, Ayda AlHammadi, Sara Al-Khawaga, Aysha Al-Malki, Jianghui Meng, Majid Alam & Joerg Buddenkotte. (2022) Neuroimmune communication regulating pruritus in atopic dermatitis. Journal of Allergy and Clinical Immunology 149:6, pages 1875-1898.
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Chenda Chheang, Stéphane Guinand, Christophe Von Garnier & Claudio Sartori. (2022) New perspectives of biological therapy for severe asthma in adults and adolescents. Swiss Medical Weekly 152:2122, pages w30176.
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Saba Al Heialy, Rakhee K. Ramakrishnan & Qutayba Hamid. (2022) Recent advances in the immunopathogenesis of severe asthma. Journal of Allergy and Clinical Immunology 149:2, pages 455-465.
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Brittany Salter, Paige Lacy & Manali Mukherjee. (2022) Biologics in Asthma: A Molecular Perspective to Precision Medicine. Frontiers in Pharmacology 12.
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Beatrice Ragnoli, Jaymin Morjaria, Patrizia Pignatti, Paolo Montuschi, Mariangela Barbieri, Lucrezia Mondini, Luca Ruggero, Liliana Trotta & Mario Malerba. (2022) Dupilumab and tezepelumab in severe refractory asthma: new opportunities. Therapeutic Advances in Chronic Disease 13, pages 204062232210973.
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Ioana Agache, Ibon Eguiluz‐Gracia, Catalina Cojanu, Alexandru Laculiceanu, Stefano Giacco, Magdalena Zemelka‐Wiacek, Anna Kosowska, Cezmi A. Akdis & Marek Jutel. (2021) Advances and highlights in asthma in 2021. Allergy 76:11, pages 3390-3407.
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Corrado Pelaia, Giulia Pelaia, Federico Longhini, Claudia Crimi, Cecilia Calabrese, Luca Gallelli, Angela Sciacqua & Alessandro Vatrella. (2021) Monoclonal Antibodies Targeting Alarmins: A New Perspective for Biological Therapies of Severe Asthma. Biomedicines 9:9, pages 1108.
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Corrado Pelaia, Giulia Pelaia, Claudia Crimi, Angelantonio Maglio, Luca Gallelli, Rosa Terracciano & Alessandro Vatrella. (2021) Tezepelumab: A Potential New Biological Therapy for Severe Refractory Asthma. International Journal of Molecular Sciences 22:9, pages 4369.
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