Search in:

Journal of Experimental Pharmacology Volume 10, 2018 - Issue

Submit an article Journal homepage

Open access

104

Views

CrossRef citations to date

Altmetric

Original Research

Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis

Suliman Al-Fayoumi1 CTI BioPharma, Seattle, WA, USACorrespondence[email protected]

Taishi Hashiguchi2 SMC Laboratories, Tokyo, Japan

Yuka Shirakata2 SMC Laboratories, Tokyo, Japan

John Mascarenhas3 Tish Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Jack W Singer1 CTI BioPharma, Seattle, WA, USA

Pages 9-17 | Published online: 09 May 2018

Cite this article
CrossMark

Full Article
Figures & data
References
Citations
Metrics
Licensing
Reprints & Permissions
View PDF PDF

Citations (11)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Articles from other publishers (11)

Ismail Sami Mahmoud, Yazun Bashir Jarrar & Febrimarsa. (2023) Modulation of IRAK enzymes as a therapeutic strategy against SARS-CoV-2 induced cytokine storm. Clinical and Experimental Medicine.
Crossref

Sandra Torres, Cristina Ortiz, Nadine Bachtler, Wenyi Gu, Leon D. Grünewald, Nico Kraus, Robert Schierwagen, Christoph Hieber, Caroline Meier, Olaf Tyc, Maximilian Joseph Brol, Frank Erhard Uschner, Bart Nijmeijer, Christoph Welsch, Marie‐Luise Berres, Carmen Garcia‐Ruiz, Jose Carlos Fernandez‐Checa, Christian Trautwein, Thomas J. Vogl, Stefan Zeuzem, Jonel Trebicka & Sabine Klein. (2023) Janus kinase 2 inhibition by pacritinib as potential therapeutic target for liver fibrosis. Hepatology 77:4, pages 1228-1240.
Crossref

Elisa Fiorentini, Francesco Bonomi, Silvia Peretti, Martina Orlandi, Gemma Lepri, Marco Matucci Cerinic, Silvia Bellando Randone & Serena Guiducci. (2022) Potential Role of JAK Inhibitors in the Treatment of Systemic Sclerosis-Associated Interstitial Lung Disease: A Narrative Review from Pathogenesis to Real-Life Data. Life 12:12, pages 2101.
Crossref

Yvette N. Lamb. (2022) Pacritinib: First Approval. Drugs 82:7, pages 831-838.
Crossref

Rioko Migita, Yasutaka Kimoto, Junki Hiura, Yuta Okumura & Takahiko Horiuchi. (2022) A Case of Rapidly Progressing Hepatocellular Carcinoma after Administration of JAK Inhibitors to Treat Rheumatoid Arthritis. Case Reports in Rheumatology 2022, pages 1-5.
Crossref

Constanze Mittermeier, Andreas Konopa & Susanne Muehlich. (2020) Molecular Mechanisms to Target Cellular Senescence in Hepatocellular Carcinoma. Cells 9:12, pages 2540.
Crossref

Yun-Ti Chen, Cheng-Hsuan Wu, Yi-Cyun Chen, Yen-Chao Hsu, Yu-Wei Huang & Jinn-Moon Yang. (2020) Configurational Differences and Binding Mechanisms of Interleukin-1 Receptor-Associated Kinase 1. Configurational Differences and Binding Mechanisms of Interleukin-1 Receptor-Associated Kinase 1.

Alain Lescoat, Marie Lelong, Mohamed Jeljeli, Claire Piquet-Pellorce, Claudie Morzadec, Alice Ballerie, Stéphane Jouneau, Patrick Jego, Laurent Vernhet, Fréderic Batteux, Olivier Fardel & Valérie Lecureur. (2020) Combined anti-fibrotic and anti-inflammatory properties of JAK-inhibitors on macrophages in vitro and in vivo: Perspectives for scleroderma-associated interstitial lung disease. Biochemical Pharmacology 178, pages 114103.
Crossref

Naeimeh Atabaki-Pasdar, Mattias Ohlsson, Ana Viñuela, Francesca Frau, Hugo Pomares-Millan, Mark Haid, Angus G. Jones, E. Louise Thomas, Robert W. Koivula, Azra Kurbasic, Pascal M. Mutie, Hugo Fitipaldi, Juan Fernandez, Adem Y. Dawed, Giuseppe N. Giordano, Ian M. Forgie, Timothy J. McDonald, Femke Rutters, Henna Cederberg, Elizaveta Chabanova, Matilda Dale, Federico De Masi, Cecilia Engel Thomas, Kristine H. Allin, Tue H. Hansen, Alison Heggie, Mun-Gwan Hong, Petra J. M. Elders, Gwen Kennedy, Tarja Kokkola, Helle Krogh Pedersen, Anubha Mahajan, Donna McEvoy, Francois Pattou, Violeta Raverdy, Ragna S. Häussler, Sapna Sharma, Henrik S. Thomsen, Jagadish Vangipurapu, Henrik Vestergaard, Leen M. ‘t Hart, Jerzy Adamski, Petra B. Musholt, Soren Brage, Søren Brunak, Emmanouil Dermitzakis, Gary Frost, Torben Hansen, Markku Laakso, Oluf Pedersen, Martin Ridderstråle, Hartmut Ruetten, Andrew T. Hattersley, Mark Walker, Joline W. J. Beulens, Andrea Mari, Jochen M. Schwenk, Ramneek Gupta, Mark I. McCarthy, Ewan R. Pearson, Jimmy D. Bell, Imre Pavo & Paul W. Franks. (2020) Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts. PLOS Medicine 17:6, pages e1003149.
Crossref

Justin Jit Hin Tang, Dexter Kai Hao Thng, Jhin Jieh Lim & Tan Boon Toh. (2020) JAK/STAT signaling in hepatocellular carcinoma. Hepatic Oncology 7:1.
Crossref

Jack W. Singer, Angela Fleischman, Suliman Al-Fayoumi, John O. Mascarenhas, Qiang Yu & Anupriya Agarwal. (2018) Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy. Oncotarget 9:70, pages 33416-33439.
Crossref

Share icon
Back to Top

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.

People also read
Recommended articles
Cited by

To cite this article:

Reference style: APA Chicago Harvard

Citation copied to clipboard

Reference styles above use APA (6th edition), Chicago (16th edition) & Harvard (10th edition)

Download citation

Download a citation file in RIS format that can be imported by citation management software including EndNote, ProCite, RefWorks and Reference Manager.

Choose format: RIS BibTex RefWorks Direct Export

Choose options: Citation Citation & abstract Citation & references

Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis

Articles from other publishers (11)

Information for

Open access

Opportunities

Help and information

Your download is now in progress and you may close this window

Login or register to access this feature

Pilot study of the antifibrotic effects of the multikinase inhibitor pacritinib in a mouse model of liver fibrosis

Citations (11)

Articles from other publishers (11)

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date