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Journal of Experimental Pharmacology Volume 12, 2020 - Issue
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Original Research

Alpha-Mangostin Improves Cardiac Hypertrophy and Fibrosis and Associated Biochemical Parameters in High-Fat/High-Glucose Diet and Low-Dose Streptozotocin Injection-Induced Type 2 Diabetic Rats

Vivian Soetikno1 Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, IndonesiaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0002-2123-6448
ORCID Icon,
Andriyani Murwantara2 Graduate Course, Faculty of Medicine, Universitas Indonesia, Jakarta10430, Indonesia
,
Prisma Andini2 Graduate Course, Faculty of Medicine, Universitas Indonesia, Jakarta10430, Indonesia
,
Fabrian Charlie2 Graduate Course, Faculty of Medicine, Universitas Indonesia, Jakarta10430, Indonesia
,
Gilbert Lazarus3 Undergraduate Course, Faculty of Medicine, Universitas Indonesia, Jakarta10430, IndonesiaORCID Iconhttps://orcid.org/0000-0002-3605-6167
ORCID Icon,
Melva Louisa1 Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, IndonesiaORCID Iconhttps://orcid.org/0000-0002-9451-0380
ORCID Icon &
Wawaimuli Arozal1 Department of Pharmacology and Therapeutics, Faculty of Medicine, Universitas Indonesia, Jakarta, 10430, Indonesia
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Pages 27-38 | Published online: 28 Jan 2020

Citations (11)

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Vivian Soetikno, Prisma Andini, Miskiyah Iskandar, Clark Christensen Matheos, Joshua Alward Herdiman, Iqbal Kevin Kyle, Muhammad Nur Imaduddin Suma, Melva Louisa & Ari Estuningtyas. (2023) Alpha-Mangosteen lessens high-fat/high-glucose diet and low-dose streptozotocin induced-hepatic manifestations in the insulin resistance rat model. Pharmaceutical Biology 61:1, pages 241-248.
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Yao Chen, Xuejiao Qie, Wei Quan, Maomao Zeng, Fang Qin, Jie Chen, Benu Adhikari & Zhiyong He. (2023) Omnifarious fruit polyphenols: an omnipotent strategy to prevent and intervene diabetes and related complication?. Critical Reviews in Food Science and Nutrition 63:20, pages 4288-4324.
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Articles from other publishers (9)

Yu-Hsien Lee, Pei-Ling Hsieh, Shih-Chi Chao, Yi-Wen Liao, Chia-Ming Liu & Cheng-Chia Yu. (2023) α-Mangostin Inhibits the Activation of Myofibroblasts via Downregulation of Linc-ROR-Mediated TGFB1/Smad Signaling. Nutrients 15:6, pages 1321.
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Wencong He, Hong Ye, Hua Li & Qianqian Gao. (2023) Alpha Mangostin Ameliorates Gestational Diabetes in Rats via Alteration of Oxidative Stress and Inflammation Reaction. International Journal of Pharmacology 19:1, pages 1-13.
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Vivian Soetikno, Andriyani Murwantara, Ahmad Aulia Jusuf & Melva Louisa. (2022) Alpha-mangostin counteracts hyperuricemia and renal dysfunction by inhibiting URAT1 renal transporter in insulin resistance rat model. Beni-Suef University Journal of Basic and Applied Sciences 11:1.
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Dina Salem Abdelaziz Elshenawy, Nehal Mohammed Ramadan, Vivian Boshra Abdo & Rehab Hamdy Ashour. (2022) Sacubitril/valsartan combination enhanced cardiac glycophagy and prevented the progression of murine diabetic cardiomyopathy. Biomedicine & Pharmacotherapy 153, pages 113382.
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Oliver John, Annals Mushunje, Noumie Surugau & Rhanye Guad. (2022) The metabolic and molecular mechanisms of α‑mangostin in cardiometabolic disorders (Review). International Journal of Molecular Medicine 50:3.
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Desak Gede Budi Krisnamurti, Erni H. Purwaningsih, Tri Juli Edi Tarigan, Vivian Soetikno & Melva Louisa. (2022) Hematological indices and their correlation with glucose control parameters in a prediabetic rat model. Veterinary World, pages 672-678.
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Yu Kakimoto, Kumiko Asakura & Motoki Osawa. (2021) Cutoff value for hypertrophic heart weight in the Japanese population. Legal Medicine 48, pages 101831.
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Hee-Sung Chae, Hyun Ji Kim, Hyun-Jeong Ko, Chang Hoon Lee, Young Hee Choi & Young-Won Chin. (2020) Transcriptome Analysis Illuminates a Hub Role of SREBP2 in Cholesterol Metabolism by α-Mangostin . ACS Omega 5:48, pages 31126-31136.
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Guangru Li, Lei Yang, Lifeng Feng, Jiu Yang, Yafei Li, Jiale An, Dihua Li, Yang Xu, Yang Gao, Jing Li, Jie Liu, Liang Yang & Zhi Qi. (2020) Syringaresinol Protects against Type 1 Diabetic Cardiomyopathy by Alleviating Inflammation Responses, Cardiac Fibrosis, and Oxidative Stress. Molecular Nutrition & Food Research 64:18, pages 2000231.
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