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Journal of Experimental Pharmacology Volume 12, 2020 - Issue

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Review

MET Inhibitors for the Treatment of Gastric Cancer: What’s Their Potential?

Haidar El Darsa1 Division of Medical Oncology, Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Alberta, Canada

Rola El Sayed2 Division of Hematology-Oncology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon

https://orcid.org/0000-0002-1711-2696

Omar Abdel-Rahman1 Division of Medical Oncology, Department of Oncology, Cross Cancer Institute, University of Alberta, Edmonton, Alberta, CanadaCorrespondence[email protected]

https://orcid.org/0000-0002-5117-2502

Pages 349-361 | Published online: 06 Oct 2020

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Jin‐Jiao Chen, Jin‐Mei Jin, Wen‐Jie Gu, Zeng Zhao, Hu Yuan, Yu‐Dong Zhou, Dale G. Nagle, Qiu‐Lei Xi, Xue‐Mei Zhang, Qing‐Yan Sun, Ye Wu, Wei‐Dong Zhang & Xin Luan. (2023) Crizotinib‐based proteolysis targeting chimera suppresses gastric cancer by promoting MET degradation . Cancer Science 114:5, pages 1958-1971.
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C. Röcken. (2022) Predictive biomarkers in gastric cancer. Journal of Cancer Research and Clinical Oncology 149:1, pages 467-481.
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Pei-Yi Chu, Wei-Chieh Huang, Shiao-Lin Tung, Chung-Ying Tsai, Chih Jung Chen, Yu-Chin Liu, Chia-Wen Lee, Yang-Hsiang Lin, Hung-Yu Lin, Cheng-Yi Chen, Chau-Ting Yeh, Kwang-Huei Lin & Hsiang-Cheng Chi. (2022) IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis. Cell & Bioscience 12:1.
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Barani Karikalan & Srikumar Chakravarthi. (2022) Target Therapy and Immunotherapy for Gastric Cancer - Recent Updates. Current Cancer Therapy Reviews 18:3, pages 202-208.
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Yakun Wang, Tianshu Liu, Gongyan Chen, Jifang Gong, Yuxian Bai, Tao Zhang, Nong Xu, Li Liu, Jianming Xu, Jianxing He, Yunpeng Liu, Li Zhang, Da Jiang, Mengzhao Wang, Jianhua Chang, Wei Li, Chunmei Bai, Jinghong Zhou, Jian Wang, Yongxin Ren, Liya Zhang, Weiguo Su, Baorui Liu, & Lin Shen. (2022) Phase Ia/Ib Study of the Selective MET Inhibitor, Savolitinib, in Patients with Advanced Solid Tumors:  Safety, Efficacy, and Biomarkers. The Oncologist 27:5, pages 342-e383.
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Wei-Chieh Huang, Jia-Hau Yen, Yu-Wen Sung, Shiao-Lin Tung, Po-Ming Chen, Pei-Yi Chu, Ya-Chi Shih, Hsiang-Cheng Chi, Yi-Ching Huang, Shih-Jei Huang & Lu‐Hai Wang. (2022) Novel function of THEMIS2 in the enhancement of cancer stemness and chemoresistance by releasing PTP1B from MET. Oncogene 41:7, pages 997-1010.
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Nadja Niclauss, Ines Gütgemann, Jonas Dohmen, Jörg C. Kalff & Philipp Lingohr. (2021) Novel Biomarkers of Gastric Adenocarcinoma: Current Research and Future Perspectives. Cancers 13:22, pages 5660.
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Ryota Tanaka, Mizue Terai, Eric Londin & Takami Sato. (2021) The Role of HGF/MET Signaling in Metastatic Uveal Melanoma. Cancers 13:21, pages 5457.
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Justus Körfer, Florian Lordick & Ulrich T. Hacker. (2021) Molecular Targets for Gastric Cancer Treatment and Future Perspectives from a Clinical and Translational Point of View. Cancers 13:20, pages 5216.
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Omar Abdel-Rahman, Karen Mulder & Jacob Easaw. (2021) Outcomes of Ramucirumab Plus Paclitaxel Among Patients With Previously Treated Metastatic Gastric/Lower Esophageal Cancer. American Journal of Clinical Oncology 44:4, pages 158-161.
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Fatemeh Moosavi, Elisa Giovannetti, Godefridus J. Peters & Omidreza Firuzi. (2021) Combination of HGF/MET-targeting agents and other therapeutic strategies in cancer. Critical Reviews in Oncology/Hematology 160, pages 103234.
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MET Inhibitors for the Treatment of Gastric Cancer: What’s Their Potential?

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MET Inhibitors for the Treatment of Gastric Cancer: What’s Their Potential?

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