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Review

Curcumin: a natural substance with potential efficacy in Alzheimer’s disease

Pages 23-31 | Published online: 03 May 2013

Keep up to date with the latest research on this topic with citation updates for this article.

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Asrin Bahmani, Zahra Najafi & Gholamabbas Chehardoli. (2022) Curcumin-Derived Heterocycles as Anticancer Agents. A Systematic Review.. Organic Preparations and Procedures International 54:6, pages 493-510.
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Articles from other publishers (27)

Sherry Sharma, Jai Bharti Sharma, Shailendra Bhatt & Manish Kumar. (2022) Optimization and Fabrication of Curcumin Loaded Solid Lipid Nanoparticles Using Box-Behnken Design for Nasal Delivery. Nanoscience & Nanotechnology-Asia 12:6.
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Sujan Bhowmick, Marzan Sarkar, Jakir Hussain, Mehedi Hassan, Mafroz Basunia, Taslima Nahar, Azizur Rahman, Borhan Uddin & Shahdat Hossain. (2021) Curcuma longa extract ameliorates motor and cognitive deficits of 6-hydroxydopamine-infused Parkinson’s disease model rats. Advances in Traditional Medicine 22:4, pages 773-787.
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Chenghuan Hua, Wenjie Yu, Mingyue Yang, Qun Cai, Tian Gao, Silong Zhang, Huan Xu, Huan He, Na Peng & Yi Liu. (2021) Casein-pectin nanocomplexes as a potential oral delivery system for improving stability and bioactivity of curcumin. Colloid and Polymer Science 299:10, pages 1557-1566.
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Nahid Ahmadi, Mir-Jamal Hosseini, Kobra Rostamizadeh & Mahdieh Anoush. (2021) Investigation of therapeutic effect of curcumin α and β glucoside anomers against Alzheimer’s disease by the nose to brain drug delivery. Brain Research 1766, pages 147517.
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Jiejian Kou, Minghui Wang, Junzhuo Shi, Haiyu Zhang, Xiaohui Pu, Shiyong Song, Cuiling Yang, Yi Yan, Yvonne Döring, Xinmei Xie & Xiaobin Pang. (2021) Curcumin Reduces Cognitive Deficits by Inhibiting Neuroinflammation through the Endoplasmic Reticulum Stress Pathway in Apolipoprotein E4 Transgenic Mice. ACS Omega 6:10, pages 6654-6662.
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Magisetty Obulesu. 2021. Turmeric and Curcumin for Neurodegenerative Diseases. Turmeric and Curcumin for Neurodegenerative Diseases 19 33 .
Eirini Chainoglou & Dimitra Hadjipavlou-Litina. (2020) Curcumin in Health and Diseases: Alzheimer’s Disease and Curcumin Analogues, Derivatives, and Hybrids. International Journal of Molecular Sciences 21:6, pages 1975.
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Ju‐Xian Song, Sandeep Malampati, Yu Zeng, Siva Sundara Kumar Durairajan, Chuan‐Bin Yang, Benjamin Chun‐Kit Tong, Ashok Iyaswamy, Wen‐Bin Shang, Sravan Gopalkrishnashetty Sreenivasmurthy, Zhou Zhu, King‐Ho Cheung, Jia‐Hong Lu, Chunzhi Tang, Nenggui Xu & Min Li. (2019) A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models. Aging Cell 19:2.
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Clara Bik-San Lau & Grace Gar-Lee Yue. 2020. Natural Products for Cancer Chemoprevention. Natural Products for Cancer Chemoprevention 209 239 .
Sandrine Cadel, Cécile Darmon, Alexandre Désert, Mouna Mahbouli, Christophe Piesse, Thanos Ghélis, René Lafont & Thierry Foulon. (2019) The effects of curcumin, mangiferin, resveratrol and other natural plant products on aminopeptidase B activity. Biochemical and Biophysical Research Communications 512:4, pages 832-837.
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Jia Meng, Yan Li, Mingming Zhang, Wenjing Li, Lin Zhou, Qiujun Wang, Lin Lin, Lihong Jiang & Wenliang Zhu. (2019) A combination of curcumin, vorinostat and silibinin reverses A β -induced nerve cell toxicity via activation of AKT-MDM2-p53 pathway . PeerJ 7, pages e6716.
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Guangfu Zhao, Xiaoyan Dong & Yan Sun. (2018) Self-Assembled Curcumin–Poly(carboxybetaine methacrylate) Conjugates: Potent Nano-Inhibitors against Amyloid β-Protein Fibrillogenesis and Cytotoxicity. Langmuir 35:5, pages 1846-1857.
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Tahira Farooqui & Akhlaq A. Farooqui. 2019. Curcumin for Neurological and Psychiatric Disorders. Curcumin for Neurological and Psychiatric Disorders 479 493 .
Omar M. E. Abdel-Salam. 2019. Pathology, Prevention and Therapeutics of Neurodegenerative Disease. Pathology, Prevention and Therapeutics of Neurodegenerative Disease 279 301 .
Aparna Krishnamoorthy, Narjes Tavoosi, Gary K. L. Chan, Jianfang Liu, Gang Ren, Giorgio Cavigiolio & Robert O. Ryan. (2018) Effect of curcumin on amyloid‐like aggregates generated from methionine‐oxidized apolipoprotein A‐I. FEBS Open Bio 8:2, pages 302-310.
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Pei Shan Lu, Baskaran Stephen Inbaraj & Bing Huei Chen. (2018) Determination of oral bioavailability of curcuminoid dispersions and nanoemulsions prepared from Curcuma longa Linnaeus . Journal of the Science of Food and Agriculture 98:1, pages 51-63.
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Johant Lakey-Beitia, Yisett González, Deborah Doens, David E. Stephens, Ricardo Santamaría, Enrique Murillo, Marcelino Gutiérrez, Patricia L. Fernández, K.S. Rao, Oleg V. Larionov & Armando A. Durant-Archibold. (2017) Assessment of Novel Curcumin Derivatives as Potent Inhibitors of Inflammation and Amyloid-β Aggregation in Alzheimer’s Disease. Journal of Alzheimer's Disease 60:s1, pages S59-S68.
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Mehmet Akif Topcuoglu & Ethem Murat Arsava. 2017. Nutrition in Neurologic Disorders. Nutrition in Neurologic Disorders 155 206 .
Anthony Taghogho Eduviere, Solomon Umukoro, Olusegun A. Adeoluwa, Itivere Adrian Omogbiya & Oritoke Modupe Aluko. (2016) Possible Mechanisms Involved in Attenuation of Lipopolysaccharide-Induced Memory Deficits by Methyl Jasmonate in Mice. Neurochemical Research 41:12, pages 3239-3249.
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Krzysztof Szczepanowicz, Danuta Jantas, Marek Piotrowski, Jakub Staroń, Monika Leśkiewicz, Magdalena Regulska, Władysław Lasoń & Piotr Warszyński. (2016) Encapsulation of curcumin in polyelectrolyte nanocapsules and their neuroprotective activity. Nanotechnology 27:35, pages 355101.
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Zhiqiang Jiang, Xiaoyan Dong, Hu Liu, Yongjian Wang, Lei Zhang & Yan Sun. (2016) Multifunctionality of self-assembled nanogels of curcumin-hyaluronic acid conjugates on inhibiting amyloid β-protein fibrillation and cytotoxicity. Reactive and Functional Polymers 104, pages 22-29.
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Akhlaq A. FarooquiAkhlaq A. Farooqui. 2016. Therapeutic Potentials of Curcumin for Alzheimer Disease. Therapeutic Potentials of Curcumin for Alzheimer Disease 369 392 .
Praveen P. N. Rao, Tarek Mohamed, Karan Teckwani & Gary Tin. (2015) Curcumin Binding to Beta Amyloid: A Computational Study. Chemical Biology & Drug Design 86:4, pages 813-820.
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Pierfausto Seneci. 2015. Chemical Modulators of Protein Misfolding and Neurodegenerative Disease. Chemical Modulators of Protein Misfolding and Neurodegenerative Disease 173 228 .
Sathya N. Prasad & Muralidhara. (2014) Mitigation of acrylamide-induced behavioral deficits, oxidative impairments and neurotoxicity by oral supplements of geraniol (a monoterpene) in a rat model. Chemico-Biological Interactions 223, pages 27-37.
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Marcos J. Guerrero-Muñoz, Diana L. Castillo-Carranza & Rakez Kayed. (2014) Therapeutic approaches against common structural features of toxic oligomers shared by multiple amyloidogenic proteins. Biochemical Pharmacology 88:4, pages 468-478.
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Sathya N. Prasad & Muralidhara. (2014) Neuroprotective effect of geraniol and curcumin in an acrylamide model of neurotoxicity in Drosophila melanogaster: Relevance to neuropathy. Journal of Insect Physiology 60, pages 7-16.
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