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Journal of Hepatocellular Carcinoma Volume 7, 2020 - Issue
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Original Research

Validation of the GALAD Model and Establishment of GAAP Model for Diagnosis of Hepatocellular Carcinoma in Chinese Patients

Miaoxia Liu1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of China;2 Hepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou510515, People’s Republic of ChinaView further author information
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Ruihong Wu1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of China;3 Phase I Clinical Research Center, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-7585-0059View further author information
ORCID Icon,
Xu Liu1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Hongqin Xu1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Xiumei Chi1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of China;3 Phase I Clinical Research Center, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-6291-8496View further author information
ORCID Icon,
Xiaomei Wang1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Mengru Zhan1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-2419-6859View further author information
ORCID Icon,
Bao Wang1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Fei Peng1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0002-5446-9854View further author information
ORCID Icon,
Xiuzhu Gao1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of China;3 Phase I Clinical Research Center, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaORCID Iconhttps://orcid.org/0000-0001-6310-1456View further author information
ORCID Icon,
Ying Shi1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Xiaoyu Wen1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Yali Ji2 Hepatology Unit, Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou510515, People’s Republic of ChinaView further author information
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Qinglong Jin1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaCorrespondence[email protected]
View further author information
&
Junqi Niu1 Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin Province130021, People’s Republic of ChinaView further author information
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Pages 219-232 | Published online: 23 Oct 2020

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Bernardo Stefanini, Matteo Tonnini, Ilaria Serio, Matteo Renzulli & Francesco Tovoli. (2022) Surveillance for hepatocellular carcinoma: current status and future perspectives for improvement. Expert Review of Anticancer Therapy 22:4, pages 371-381.
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Ting Sun, Ruicen Li, Yiwen Qiu, Shu Shen & Wentao Wang. (2021) New Thresholds for AFP and Des-γ-Carboxy Prothrombin in Chronic Liver Disease Depending on the Use of Nucleoside Analogs and an Integrated Nomogram. International Journal of General Medicine 14, pages 6149-6165.
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Articles from other publishers (11)

Yongwu Chen, Xiuli Yang, Yanfei Shao, Hongying Zhao, Jinying Jiang, Ping Huang, Yi Lu & Zixue Xuan. (2023) Comparison of diagnostic performance of AFP, DCP and two diagnostic models in hepatocellular carcinoma: a retrospective study. Annals of Hepatology 28:4, pages 101099.
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Yi‐Te Lee, Naoto Fujiwara, Ju Dong Yang & Yujin Hoshida. (2023) Risk stratification and early detection biomarkers for precision HCC screening. Hepatology 78:1, pages 319-362.
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Jia-Mei Dong, Rui-Qi Wang, Ning-Ning Yuan, Jia-Hao Guo, Xin-Yang Yu, Ang-Hui Peng, Jia-Yi Cai, Lei Xue, Zhi-Ling Zhou, Yi-Hao Sun & Ying-Yin Chen. (2023) Recent advances in optical aptasensors for biomarkers in early diagnosis and prognosis monitoring of hepatocellular carcinoma. Frontiers in Cell and Developmental Biology 11.
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Endrit Shahini, Giuseppe Pasculli, Antonio Giovanni Solimando, Claudio Tiribelli, Raffaele Cozzolongo & Gianluigi Giannelli. (2023) Updating the Clinical Application of Blood Biomarkers and Their Algorithms in the Diagnosis and Surveillance of Hepatocellular Carcinoma: A Critical Review. International Journal of Molecular Sciences 24:5, pages 4286.
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Ming-Cheng Guan, Shi-Yu Zhang, Qian Ding, Na Li, Ting-Ting Fu, Gui-Xia Zhang, Qian-Qian He, Feng Shen, Tian Yang & Hong Zhu. (2023) The Performance of GALAD Score for Diagnosing Hepatocellular Carcinoma in Patients with Chronic Liver Diseases: A Systematic Review and Meta-Analysis. Journal of Clinical Medicine 12:3, pages 949.
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Ping Chen, Haolin Song, Wei Xu, Jin Guo, Jianfei Wang, Juhong Zhou, Xiang Kang, Chaolei Jin, Yubo Cai, Zixuan Feng, Hainv Gao, Fengmin Lu & Lanjuan Li. (2022) Validation of the GALAD model and establishment of a new model for HCC detection in Chinese patients. Frontiers in Oncology 12.
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Sophie Schlosser, Deniz Tümen, Barbara Volz, Katja Neumeyer, Niklas Egler, Claudia Kunst, Hauke Christian Tews, Stephan Schmid, Arne Kandulski, Martina Müller & Karsten Gülow. (2022) HCC biomarkers – state of the old and outlook to future promising biomarkers and their potential in everyday clinical practice. Frontiers in Oncology 12.
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Si-Yu Liu, Chao Li, Li-Yang Sun, Ming-Cheng Guan, Li-Hui Gu, Dong-Xu Yin, Lan-Qing Yao, Lei Liang, Ming-Da Wang, Hao Xing, Hong Zhu, Timothy M. Pawlik, Wan Yee Lau, Feng Shen, Xiang-Min Tong & Tian Yang. (2022) ASAP Score versus GALAD Score for detection of hepatitis C-related hepatocellular carcinoma: A multicenter case-control analysis. Frontiers in Oncology 12.
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Chenjun Huang, Meng Fang, Xiao Xiao, Hong Wang, Zhiyuan Gao, Jun Ji, Lijuan Liu, Erli Gu, Ya Li, Mengmeng Wang & Chunfang Gao. (2021) Validation of the GALAD model for early diagnosis and monitoring of hepatocellular carcinoma in Chinese multicenter study. Liver International 42:1, pages 210-223.
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Nia Adeniji & Renumathy Dhanasekaran. (2021) Current and Emerging Tools for Hepatocellular Carcinoma Surveillance. Hepatology Communications 5:12, pages 1972-1986.
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Chunye Zhang & Ming Yang. (2021) The Emerging Factors and Treatment Options for NAFLD-Related Hepatocellular Carcinoma. Cancers 13:15, pages 3740.
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