Stressor-Induced Reduction in Cognitive Behavior is Associated with Impaired Colonic Mucus Layer Integrity and is Dependent Upon the LPS-Binding Protein Receptor CD14

Robert M Jaggers1 Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, 43205, USA

Damon J DiSabato2 Institute for Behavioral Medicine Research, Columbus, OH, 43210, USA;3 Department of Neuroscience, The Ohio State University, Columbus, OH, 43210, USA

Brett R Loman1 Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, 43205, USA

Danica Kontic1 Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, 43205, USA

Kyle D Spencer1 Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, 43205, USA;4 Department of Biomedical Informatics, The Ohio State University, Columbus, OH, USA;5 Graduate Partnership Program, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, OH, USA

Jacob M Allen1 Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, 43205, USA

Jonathan P Godbout2 Institute for Behavioral Medicine Research, Columbus, OH, 43210, USA;3 Department of Neuroscience, The Ohio State University, Columbus, OH, 43210, USA

Ning Quan6 Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, Jupiter, FL, 33458, USA

Tamar L Gur2 Institute for Behavioral Medicine Research, Columbus, OH, 43210, USA;7 Department of Psychiatry, College of Medicine, The Ohio State University, Columbus, OH, 43210, USA

Michael T Bailey1 Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children’s Hospital, Columbus, OH, 43205, USA;2 Institute for Behavioral Medicine Research, Columbus, OH, 43210, USA;8 Department of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH, 43210, USACorrespondence[email protected]

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Stressor-Induced Reduction in Cognitive Behavior is Associated with Impaired Colonic Mucus Layer Integrity and is Dependent Upon the LPS-Binding Protein Receptor CD14

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Stressor-Induced Reduction in Cognitive Behavior is Associated with Impaired Colonic Mucus Layer Integrity and is Dependent Upon the LPS-Binding Protein Receptor CD14

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