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Journal of Inflammation Research Volume 15, 2022 - Issue
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ORIGINAL RESEARCH

Apelin-13 Attenuates Lipopolysaccharide-Induced Inflammatory Responses and Acute Lung Injury by Regulating PFKFB3-Driven Glycolysis Induced by NOX4-Dependent ROS

Yafei Yuan1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Wei Wang1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Yue Zhang1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Qiaohui Hong1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Wenhui Huang1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Lijuan Li1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Zhanzhan Xie1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Yixin Chen1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China
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Xu Li2 Department of Emergency Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China;3 Ministry of Education, Key Laboratory of Hainan Trauma and Disaster Rescue, College of Emergency and Trauma, Hainan Medical University, Haikou, 571199, People’s Republic of ChinaCorrespondence[email protected]
&
Ying Meng1 Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence[email protected]
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Pages 2121-2139 | Published online: 30 Mar 2022

Citations (10)

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Read on this site (1)

Min Xiao, Dadong Liu, Yao Xu, Wenjian Mao & Weiqin Li. (2023) Role of PFKFB3-driven glycolysis in sepsis. Annals of Medicine 55:1, pages 1278-1289.
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Articles from other publishers (9)

Jingqian Su, Shun Wu, Fen Zhou & Zhiyong Tong. (2023) Research Progress of Macromolecules in the Prevention and Treatment of Sepsis. International Journal of Molecular Sciences 24:16, pages 13017.
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Jiawei Xu, Yunpeng Zhang, Rong Gan, Zhuoqi Liu & Yan Deng. (2023) Identification and validation of lactate metabolism-related genes in oxygen-induced retinopathy. Scientific Reports 13:1.
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Ge Gong, Wenhui Wan, Xinhui Liu & Jian Yin. (2023) Apelin-13, a regulator of autophagy, apoptosis and inflammation in multifaceted bone protection. International Immunopharmacology 117, pages 109991.
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Guo-wei Tu, Yi Zhang, Jie-fei Ma, Jun-yi Hou, Guang-wei Hao, Ying Su, Jing-chao Luo, Lulu Sheng & Zhe Luo. (2023) Extracellular vesicles derived from CD4+ T cells carry DGKK to promote sepsis-induced lung injury by regulating oxidative stress and inflammation. Cellular & Molecular Biology Letters 28:1.
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Tianpeng Huang, Danyang Chen, Wei Ye, Wenwen Chen, Min Zhang, Jiale Hao, Licong Xu, Xiaoqing Bai & Sunzhong Mao. (2023) Effect and mechanism of apelin on lipopolysaccharide induced acute pulmonary vascular endothelial barrier dysfunction. Scientific Reports 13:1.
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Huang Liu, Qingqiang Shi, Ling Tang, Hanghang Wang & Daoxin Wang. (2023) APELIN-13 AMELIORATES LPS-INDUCED ENDOTHELIAL-TO-MESENCHYMAL TRANSITION AND POST–ACUTE LUNG INJURY PULMONARY FIBROSIS BY SUPPRESSING TRANSFORMING GROWTH FACTOR-Β1 SIGNALING. Shock 59:1, pages 108-117.
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Rumei Luan, Dongyan Ding & Junling Yang. (2022) The protective effect of natural medicines against excessive inflammation and oxidative stress in acute lung injury by regulating the Nrf2 signaling pathway. Frontiers in Pharmacology 13.
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Meng Ning, Yingwu Liu, Donglian Wang, Jin Wei, Guoyong Hu & Pengcheng Xing. (2022) Knockdown of TRIM27 alleviated sepsis-induced inflammation, apoptosis, and oxidative stress via suppressing ubiquitination of PPARγ and reducing NOX4 expression. Inflammation Research 71:10-11, pages 1315-1325.
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Xu Wang, Lu Zhang, Peisen Li, Yafei Zheng, Yanjie Yang & Shaoping Ji. (2022) Apelin/APJ system in inflammation. International Immunopharmacology 109, pages 108822.
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