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Journal of Pain Research Volume 9, 2016 - Issue

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Original Research

Efficacy, tolerability, and safety of an oral enzyme combination vs diclofenac in osteoarthritis of the knee: results of an individual patient-level pooled reanalysis of data from six randomized controlled trials

Michael A Ueberall1 Institute of Neurological Sciences, NurembergCorrespondence[email protected]

Gerhard HH Mueller-Schwefe2 Interdisciplinary Center for Pain and Palliative Care Medicine, Göppingen

Rainer Wigand3 Interdisciplinary Center for Rheumatology and Immunology, Frankfurt

Ute Essner4 O.Meany Consultancy, Hamburg, Germany

Pages 941-961 | Published online: 04 Nov 2016

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Articles from other publishers (3)

Yan-Tao Ma, Yu-Lin Dong, Bo Wang, Wen-Pin Xie, Qiang-Min Huang & Yong-Jun Zheng. (2023) Dry needling on latent and active myofascial trigger points versus oral diclofenac in patients with knee osteoarthritis: a randomized controlled trial. BMC Musculoskeletal Disorders 24:1.
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Yves E. Henrotin, Christoph Michlmayr, Stefanie M. Rau, Anne-Marie Quirke, Marco Bigoni & Michael A. Ueberall. (2022) Combination of Enzymes and Rutin to Manage Osteoarthritis Symptoms: Lessons from a Narrative Review of the Literature. Rheumatology and Therapy 9:5, pages 1305-1327.
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Amit Bhatia, Vijay Goni, Shruti Chopra, Bhupinder Singh & Om Prakash Katare. (2020) Evaluation of efficacy and safety of a novel lipogel containing diclofenac: A randomized, placebo controlled, double-blind clinical trial in patients with signs and symptoms of osteoarthritis. Contemporary Clinical Trials Communications 20, pages 100664.
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