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Original Research

A randomized, Phase IIb study investigating oliceridine (TRV130), a novel µ-receptor G-protein pathway selective (μ-GPS) modulator, for the management of moderate to severe acute pain following abdominoplasty

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Pages 2413-2424 | Published online: 06 Oct 2017

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Read on this site (15)

Neil Daksla, Ashley Wang, Zhaosheng Jin, Abhishek Gupta & Sergio D Bergese. (2023) Oliceridine for the Management of Moderate to Severe Acute Postoperative Pain: A Narrative Review. Drug Design, Development and Therapy 17, pages 875-886.
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Jingwen Niu, Wenmin Hu, Yuntao Lu & Hui Tang. (2023) Efficacy and safety of oliceridine treatment in patients with postoperative pain: a systematic review and meta-analysis of randomized controlled trials. Expert Review of Clinical Pharmacology 16:6, pages 589-599.
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Qiu Qiu, Joshua CJ Chew & Michael G Irwin. (2022) Opioid MOP receptor agonists in late-stage development for the treatment of postoperative pain. Expert Opinion on Pharmacotherapy 23:16, pages 1831-1843.
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Eugene R. Viscusi. (2022) A critical review of oliceridine injection as an IV opioid analgesic for the management of severe acute pain. Expert Review of Neurotherapeutics 22:6, pages 419-426.
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Ammar A.H. Azzam & David G. Lambert. (2022) Preclinical discovery and development of oliceridine (Olinvyk®) for the treatment of post-operative pain. Expert Opinion on Drug Discovery 17:3, pages 215-223.
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Jill E. Elwing, Hadi Atassi, Benjamin D. Rogers & Gregory S. Sayuk. (2022) Emerging therapies in the management of Irritable Bowel Syndrome (IBS). Expert Opinion on Emerging Drugs 27:1, pages 55-73.
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Zhaosheng Jin, Mingxi Zhu, Abhishek Gupta, Christopher Page, Tong J Gan & Sergio D Bergese. (2022) Evaluating oliceridine as a treatment option for moderate to severe acute post-operative pain in adults. Expert Opinion on Pharmacotherapy 23:1, pages 9-17.
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Hon Sen Tan & Ashraf S Habib. (2021) Oliceridine: A Novel Drug for the Management of Moderate to Severe Acute Pain – A Review of Current Evidence. Journal of Pain Research 14, pages 969-979.
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Hon Sen Tan & Ashraf S. Habib. (2021) Safety evaluation of oliceridine for the management of postoperative moderate-to-severe acute pain. Expert Opinion on Drug Safety 20:11, pages 1291-1298.
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Abhishek K Gupta, Shayla Mena, Zhaosheng Jin, Tong J Gan & Sergio Bergese. (2021) Postoperative pain: a review of emerging therapeutic options. Expert Review of Neurotherapeutics 21:10, pages 1085-1100.
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Apoorva Phadke & Purnima Amin. (2021) A Recent Update on Drug Delivery Systems for Pain Management. Journal of Pain & Palliative Care Pharmacotherapy 35:3, pages 175-214.
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Sergio D Bergese, Marek Brzezinski, Gregory B Hammer, Timothy L Beard, Peter H Pan, Sharon E Mace, Richard D Berkowitz, Kristina Cochrane, Linda Wase, Harold S Minkowitz & Ashraf S Habib. (2019) ATHENA: A Phase 3, Open-Label Study Of The Safety And Effectiveness Of Oliceridine (TRV130), A G-Protein Selective Agonist At The µ-Opioid Receptor, In Patients With Moderate To Severe Acute Pain Requiring Parenteral Opioid Therapy. Journal of Pain Research 12, pages 3113-3126.
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Gary M. Oderda, Anthony J. Senagore, Kellie Morland, Sheikh Usman Iqbal, Marla Kugel, Sizhu Liu & Ashraf S. Habib. (2019) Opioid-related respiratory and gastrointestinal adverse events in patients with acute postoperative pain: prevalence, predictors, and burden. Journal of Pain & Palliative Care Pharmacotherapy 33:3-4, pages 82-97.
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Aliza T. Ehrlich, Brigitte L. Kieffer & Emmanuel Darcq. (2019) Current strategies toward safer mu opioid receptor drugs for pain management. Expert Opinion on Therapeutic Targets 23:4, pages 315-326.
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