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Original Research

Risk of respiratory depression with opioids and concomitant gabapentinoids

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Pages 2635-2641 | Published online: 10 Nov 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Ceyda Teker, Rukiye Aslan, Cahit İpekçi, Mehmet Tokdemir & Serap Annette Akgür. (2023) Pregabalin Qualitative Detection in Turkish Forensic Cases Between 2017 to 2018. Journal of Psychoactive Drugs 0:0, pages 1-7.
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Marine Tambon, Berenice Montarnal, Marianne Lepetit & Maryse Lapeyre-Mestre. (2023) Non-opioid antinociceptive drugs : risk of respiratory depression and death related to concomitant use of gabapentinoids in addition to opioids. Expert Opinion on Drug Safety 22:3, pages 183-194.
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Udo Bonnet, Ann-Kristin Kanti, Norbert Scherbaum & Michael Specka. (2023) The Role of Gabapentinoids in the Substance Use Pattern of Adult Germans Seeking Inpatient Detoxification Treatment – A Pilot Study. Journal of Psychoactive Drugs 55:1, pages 102-111.
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Jennifer M. Byrne, Paula Mesarwi, Kyle P. Edmonds & Rabia S. Atayee. (2022) Dexmedetomidine Continuous Infusion for Refractory Cancer Pain at End of Life: A Case Report. Journal of Pain & Palliative Care Pharmacotherapy 36:3, pages 200-206.
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Jessica F. Jones, Jeremy M. Hirst, Kyle P. Edmonds & Rabia S. Atayee. (2021) A Case Report of Phenobarbital for Proportionate Sedation to Control Refractory Symptoms at the End of Life in an Opioid Tolerant Patient. Journal of Pain & Palliative Care Pharmacotherapy 35:3, pages 167-174.
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Articles from other publishers (21)

Shawn M. Flynn & Charles P. France. (2023) Effects of Gabapentinoids on Heroin-Induced Ventilatory Depression and Reversal by Naloxone. ACS Pharmacology & Translational Science 6:4, pages 519-525.
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Jongsung Hahn, Youngkwon Jo, So Hee Yoo, Jaekyu Shin, Yun Mi Yu & Young-Mi Ah. (2022) Risk of major adverse events associated with gabapentinoid and opioid combination therapy: A systematic review and meta-analysis. Frontiers in Pharmacology 13.
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Abisola Olopoenia, Wendy Camelo-Castillo, Danya M. Qato, Adepeju Adekoya, Frank Palumbo, Leah Sera & Linda Simoni-Wastila. (2022) Adverse outcomes associated with concurrent gabapentin, opioid, and benzodiazepine utilization: A nested case-control study. The Lancet Regional Health - Americas 13, pages 100302.
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Thanh Gia Tu, Sohrab Sadeghi, Rabia Atayee & Kelly Lee. (2021) Gabapentinoid Dosing and Associated Toxicities in Patients With or Without Concomitant Opioids During Hospitalization. American Journal of Hospice and Palliative Medicine® 39:5, pages 530-534.
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Swarnali Goswami, Sujith Ramachandran, Manvi Sharma & Marie Barnard. (2022) Gabapentin and Opioids Utilization in Patients With Diabetic Neuropathy Enrolled in Medicare (2012–2016): A Cohort Study. Journal of Pharmacy Practice, pages 089719002210871.
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Kenil Patel, Paul M. Stranges, Aimee Bobko, Connie H. Yan & Mathew Thambi. (2022) Changes in postoperative inpatient and outpatient opioid utilization after pharmacist‐led order set standardization and education for total knee and hip replacement at an academic medical center. JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY 5:2, pages 163-173.
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Abisola Olopoenia, Wendy Camelo-Castillo, Danya M. Qato, Adepeju Adekoya, Frank Palumbo, Leah Sera & Linda Simoni-Wastila. (2022) Patterns of opioid and benzodiazepine use with gabapentin among disabled Medicare beneficiaries – A retrospective cohort study. Drug and Alcohol Dependence 230, pages 109180.
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Amanj Kurdi. (2021) Opioids and Gabapentinoids Utilisation and Their Related-Mortality Trends in the United Kingdom Primary Care Setting, 2010–2019: A Cross-National, Population-Based Comparison Study. Frontiers in Pharmacology 12.
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Nebojsa Nick Knezevic, Tabish Aijaz, Alvaro Camacho-Ortega & Kenneth D Candido. (2021) A Retrospective Analysis of Gabapentinoid and Opioids to Opioid Monotherapy for Pain Relief in Patients with Chronic Neck and Low Back Pain. Pain Medicine 22:8, pages 1760-1766.
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Payal H. Desai, Olesya Taylor, Kunal J. Shah, Kirk E. Evoy & Alyssa M. Peckham. (2021) Characterization of hospitalized patients who received naloxone while receiving opioids with or without gabapentinoids. Mental Health Clinician 11:4, pages 225-230.
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Karl Winckel, Mark Daglish, David Pache & Samantha A. Hollingworth. (2020) Time to rethink our approach to the Pharmaceutical Benefits Scheme (PBS) listing of medicines: the case of pregabalin. Australian Health Review 45:2, pages 261-262.
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Yang Xiang, Hangyu Ji, Yujia Zhou, Fang Li, Jingcheng Du, Laila Rasmy, Stephen Wu, W Jim Zheng, Hua Xu, Degui Zhi, Yaoyun Zhang & Cui Tao. (2020) Asthma Exacerbation Prediction and Risk Factor Analysis Based on a Time-Sensitive, Attentive Neural Network: Retrospective Cohort Study. Journal of Medical Internet Research 22:7, pages e16981.
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Daniel Kapustin, Anuj Bhatia, Aidan McParland, Aditya Trivedi, Alexandra Davidson, Richard Brull & Mandeep Singh. (2020) Evaluating the impact of gabapentinoids on sleep health in patients with chronic neuropathic pain: a systematic review and meta-analysis. Pain 161:3, pages 476-490.
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Carla R. Jungquist, Ann Quinlan-Colwell, April Vallerand, Heather L. Carlisle, Maureen Cooney, Susan J. Dempsey, Danielle Dunwoody, Angelika Maly, Kathy Meloche, Ashley Meyers, Jason Sawyer, Navdeep Singh, Denise Sullivan, Chris Watson & Rosemary C. Polomano. (2020) American Society for Pain Management Nursing Guidelines on Monitoring for Opioid-Induced Advancing Sedation and Respiratory Depression: Revisions. Pain Management Nursing 21:1, pages 7-25.
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Ji-cheng Hu, Xiao-qing Chai, Di Wang, Shu-hua Shu, Costan G. Magnussen, Li-xia Xie & Shan-shan Hu. (2020) Intraoperative Flurbiprofen Treatment Alters Immune Checkpoint Expression in Patients Undergoing Elective Thoracoscopic Resection of Lung Cancer. Medical Principles and Practice 29:2, pages 150-159.
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Alex J. Fauer, Matthew A. Davis, Sung Won Choi, Lauren P. Wallner & Christopher R. Friese. (2019) Use of gabapentinoid medications among US adults with cancer, 2005–2015. Supportive Care in Cancer 28:1, pages 5-8.
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Awdishu, Singh, Saunders, Yam, Hirsch, Lorentz, Atayee, Ma, Tsunoda, Namba, Mnatzaganian, Painter, Watanabe, Lee, Daniels & Morello. (2019) Advancing Pharmacist Collaborative Care within Academic Health Systems. Pharmacy 7:4, pages 142.
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Amanda H. Kumar & Ashraf S. Habib. (2019) The role of gabapentinoids in acute and chronic pain after surgery. Current Opinion in Anaesthesiology 32:5, pages 629-634.
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Mieke A. Soens, Jingui He & Brian T. Bateman. (2019) Anesthesia considerations and post-operative pain management in pregnant women with chronic opioid use. Seminars in Perinatology 43:3, pages 149-161.
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Alyssa M. Peckham, Kathleen A. Fairman & David A. Sclar. (2018) Authors’ Reply to: Tomoyuki Kawada’s Comment on: “All-Cause and Drug-Related Medical Events Associated with Overuse of Gabapentin and/or Opioid Medications: A Retrospective Cohort Analysis of a Commercially Insured US Population’’. Drug Safety 41:6, pages 643-644.
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Tomoyuki Kawada. (2018) Comment on: “All-Cause and Drug-Related Medical Events Associated with Overuse of Gabapentin and/or Opioid Medications: A Retrospective Cohort Analysis of a Commercially Insured US Population”. Drug Safety 41:6, pages 641-642.
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