311
Views
66
CrossRef citations to date
0
Altmetric
Review

Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique

, , &
Pages 313-326 | Published online: 12 Jun 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Kylie E. Nash, Keat Ghee Ong & Robert E. Guldberg. (2022) Implantable biosensors for musculoskeletal health. Connective Tissue Research 63:3, pages 228-242.
Read now
Björn Gerdle & Bijar Ghafouri. (2020) Proteomic studies of common chronic pain conditions - a systematic review and associated network analyses. Expert Review of Proteomics 17:6, pages 483-505.
Read now
Hatice Kumru, Sergiu Albu, Joan Vidal & Josep Maria Tormos. (2017) Effectiveness of repetitive trancranial or peripheral magnetic stimulation in neuropathic pain. Disability and Rehabilitation 39:9, pages 856-866.
Read now
Monica Joelsson, Susanne Bernhardsson & Maria E. H. Larsson. (2017) Patients with chronic pain may need extra support when prescribed physical activity in primary care: a qualitative study. Scandinavian Journal of Primary Health Care 35:1, pages 64-74.
Read now

Articles from other publishers (61)

Roberto Bonanni, Sonia Gino Grillo, Ida Cariati, Lucia Tranquillo, Riccardo Iundusi, Elena Gasbarra, Virginia Tancredi & Umberto Tarantino. (2023) Osteosarcopenia and Pain: Do We Have a Way Out?. Biomedicines 11:5, pages 1285.
Crossref
Vladimíra Fejfarová, Radka Jarošíková, Jan Polák, Blanka Sommerová, Jitka Husáková, Veronika Wosková, Michal Dubský & Petr Tůma. (2023) Microdialysis as a tool for antibiotic assessment in patients with diabetic foot: a review. Frontiers in Endocrinology 14.
Crossref
Thangamani Ramalingam, Pooja Desai, Dhruvi Ghoghari, Vidhi Jethva & Rushvi Shah. (2023) Neurophysiology of pain education knowledge, pain disability, patient satisfaction and central sensitization in chronic musculoskeletal pain. IP Journal of Surgery and Allied Sciences 4:4, pages 137-141.
Crossref
Hajer Jasim. (2023) Topical review – salivary biomarkers in chronic muscle pain. Scandinavian Journal of Pain 23:1, pages 3-13.
Crossref
K. Sinha, Z. Uddin, H.I. Kawsar, S. Islam, M.J. Deen & M.M.R. Howlader. (2023) Analyzing chronic disease biomarkers using electrochemical sensors and artificial neural networks. TrAC Trends in Analytical Chemistry 158, pages 116861.
Crossref
Niki Bahrampour, Ariyo Movahedi, Abolghassem Djazayery & Cain C. T. Clark. (2022) The relationship between dietary sulfur amino acids intake and severity and frequency of pain in Iranian patients with musculoskeletal pains, 2020. BMC Research Notes 15:1.
Crossref
Antonio J. Varela & Kathryn W. Van Asselt. (2022) The relationship between psychosocial factors and reported disability: the role of pain self-efficacy. BMC Musculoskeletal Disorders 23:1.
Crossref
Nicholas Jacob Snow, Megan Christine Kirkland, Matthew Bruce Downer, Hannah Margaret Murphy & Michelle Ploughman. (2022) Transcranial magnetic stimulation maps the neurophysiology of chronic noncancer pain: A scoping review. Medicine 101:46, pages e31774.
Crossref
Bijar Ghafouri, Malin Ernberg, Paulin Andréll, Emmanuel Bäckryd, Marcelo Rivano Fisher, Yvonne Freund-Levi, Henrik Grelz, Olaf Gräbel, Rolf Karlsten, Eva Kosek, Monika Löfgren, Åsa Ringqvist, Karin Rudling, Britt-Marie Stålnacke, Niklas Sörlén, Karin Uhlin, Hans Westergren & Björn Gerdle. (2022) Swedish Chronic Pain Biobank: protocol for a multicentre registry and biomarker project. BMJ Open 12:11, pages e066834.
Crossref
Ömer Elma, Katherine Brain & Huan-Ji Dong. (2022) The Importance of Nutrition as a Lifestyle Factor in Chronic Pain Management: A Narrative Review. Journal of Clinical Medicine 11:19, pages 5950.
Crossref
Wolfgang Laube. (2022) Teil 2: Muskeldysfunktionen – mit Training gegen SchmerzPart 2: Muscle dysfunction—counteracting pain with training. Manuelle Medizin 60:3, pages 129-135.
Crossref
Yaron Haviv, Olga Georgiev, Tal Gaver-Bracha, Sharleen Hamad, Alina Nemirovski, Rivka Hadar, Yair Sharav, Doron J. Aframian, Yariv Brotman & Joseph Tam. (2022) Reduced Endocannabinoid Tone in Saliva of Chronic Orofacial Pain Patients. Molecules 27:14, pages 4662.
Crossref
Małgorzata Starzec-Proserpio, Marcela Grigol Bardin, Julie Fradette, Le Mai Tu, Yves Bérubè-Lauzière, Josianne Paré, Marie-Soleil Carroll & Mélanie Morin. (2022) High-Intensity Laser Therapy (HILT) as an Emerging Treatment for Vulvodynia and Chronic Musculoskeletal Pain Disorders: A Systematic Review of Treatment Efficacy. Journal of Clinical Medicine 11:13, pages 3701.
Crossref
Roberto Bonanni, Ida Cariati, Virginia Tancredi, Riccardo Iundusi, Elena Gasbarra & Umberto Tarantino. (2022) Chronic Pain in Musculoskeletal Diseases: Do You Know Your Enemy?. Journal of Clinical Medicine 11:9, pages 2609.
Crossref
Simone Battista, Andrea Dell'Isola, Mattia Manoni, Martin Englund, Alvisa Palese & Marco Testa. (2021) Experience of the COVID-19 pandemic as lived by patients with hip and knee osteoarthritis: an Italian qualitative study. BMJ Open 11:10, pages e053194.
Crossref
A. I. Levashova, M. A. Myagkova & I. A. Moseikin. (2021) Immunochemical and Electromyographic Indicators for Assessment of Pain Status in Reflex Syndrome. Neuroscience and Behavioral Physiology 51:8, pages 1066-1072.
Crossref
Simone Battista, Luca Buzzatti, Marialuisa Gandolfi, Cinzia Finocchi, Luca Falsiroli Maistrello, Antonello Viceconti, Benedetto Giardulli & Marco Testa. (2021) The Use of Botulinum Toxin A as an Adjunctive Therapy in the Management of Chronic Musculoskeletal Pain: A Systematic Review with Meta-Analysis. Toxins 13:9, pages 640.
Crossref
Seira Sato, Sho Ukimoto, Takashi Kanamoto, Nao Sasaki, Takao Hashimoto, Hikaru Saito, Eisuke Hida, Tomoharu Sato, Tatsuo Mae & Ken Nakata. (2021) Chronic musculoskeletal pain, catastrophizing, and physical function in adult women were improved after 3-month aerobic-resistance circuit training. Scientific Reports 11:1.
Crossref
Dong Huang, Yan-Qing Liu, Ling-Jie Xia, Xian-Guo Liu, Ke Ma, Guang-Zhao Liu, Li-Zu Xiao, Tao Song, Xiao-Qiu Yang, Zhi-Jian Fu & Min Yan. (2021) Expert consensus of Chinese Association for the Study of Pain on the non-opioid analgesics for chronic musculoskeletal pain. World Journal of Clinical Cases 9:9, pages 2068-2076.
Crossref
Bijar Ghafouri, Karin Wåhlén, Ulrika Wentzel-Olausson & Staffan Smeds. (2021) The Dynamic Computer Workstation—A Pilot Study of Clinical and Biochemical Investigation during Work at Static Respectively Mobile Keyboards. International Journal of Environmental Research and Public Health 18:4, pages 1493.
Crossref
Régis Junior Muniz, Mariane Schäffer Castro, Jairo Alberto Dussán-Sarria, Wolnei Caumo & Andressa de Souza. (2021) Pain catastrophizing in daughters of women with fibromyalgia: a case-control study. Brazilian Journal of Anesthesiology (English Edition).
Crossref
Teemu Zetterman, Ritva Markkula & Eija Kalso. (2021) Glucose tolerance in fibromyalgia. Medicine 100:46, pages e27803.
Crossref
Tatsunori Ikemoto, Yukiko Shiro, Kayo Ikemoto, Kazuhiro Hayashi, Young-Chang Arai, Masataka Deie, Lee Beeston, Bradley Wood & Michael Nicholas. (2020) Feasibility of Imported Self-Management Program for Elderly People with Chronic Pain: A Single-Arm Confirmatory Trial. Pain and Therapy 9:2, pages 583-599.
Crossref
Nikolaos Christidis, Pegah Baghernejad, Aylin Deyhim & Hajer Jasim. (2020) Salivary Alpha-Amylase in Experimentally-Induced Muscle Pain. Diagnostics 10:9, pages 722.
Crossref
Golnaz Barjandi, Sofia Louca Jounger, Monika Löfgren, Indre Bileviciute‐Ljungar, Eva Kosek & Malin Ernberg. (2019) Plasma tryptophan and kynurenine in females with temporomandibular disorders and fibromyalgia—An exploratory pilot study. Journal of Oral Rehabilitation 47:2, pages 150-157.
Crossref
A.I. Levashova, M.A. Myagkova & I.A. Moseikin. (2020) Immunochemical and electromyographic indicators for assessment of pain status in myofascial back pain syndrome. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova 120:12, pages 73.
Crossref
Mao Shibata, Toshiharu Ninomiya, Kozo Anno, Hiroshi Kawata, Rie Iwaki, Ryoko Sawamoto, Chiharu Kubo, Yutaka Kiyohara, Nobuyuki Sudo & Masako Hosoi. (2020) Parenting style during childhood is associated with the development of chronic pain and a patient's need for psychosomatic treatment in adulthood. Medicine 99:29, pages e21230.
Crossref
Damián Escribano & Fernando Tecles. 2020. Saliva in Health and Disease. Saliva in Health and Disease 293 319 .
Björn Gerdle, Emmanuel Bäckryd, Torkel Falkenberg, Erik Lundström & Bijar Ghafouri. (2019) Changes in inflammatory plasma proteins from patients with chronic pain associated with treatment in an interdisciplinary multimodal rehabilitation program – an explorative multivariate pilot study. Scandinavian Journal of Pain 20:1, pages 125-138.
Crossref
Mark A. Messerli & Anyesha Sarkar. (2019) Advances in Electrochemistry for Monitoring Cellular Chemical Flux. Current Medicinal Chemistry 26:26, pages 4984-5002.
Crossref
Joyce Oi Suet Cheng & Sheung-Tak Cheng. (2019) Effectiveness of physical and cognitive-behavioural intervention programmes for chronic musculoskeletal pain in adults: A systematic review and meta-analysis of randomised controlled trials. PLOS ONE 14:10, pages e0223367.
Crossref
Hajer Jasim, Anders Carlsson, Björn Gerdle, Malin Ernberg & Bijar Ghafouri. (2019) Diurnal variation of inflammatory plasma proteins involved in pain. PAIN Reports 4:5, pages e776.
Crossref
Michael J. Fischer, Gergo Horvath, Martin Krismer, Erich Gnaiger, Georg Goebel & Dominik H. Pesta. (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskeletal Disorders 19:1.
Crossref
Giacomo Rossettini, Elisa Carlino & Marco Testa. (2018) Clinical relevance of contextual factors as triggers of placebo and nocebo effects in musculoskeletal pain. BMC Musculoskeletal Disorders 19:1.
Crossref
Hajer Jasim, Anders Carlsson, Britt Hedenberg-Magnusson, Bijar Ghafouri & Malin Ernberg. (2018) Saliva as a medium to detect and measure biomarkers related to pain. Scientific Reports 8:1.
Crossref
Line Bay Sørensen, Parisa Gazerani, Karin Wåhlén, Nazdar Ghafouri, Björn Gerdle & Bijar Ghafouri. (2018) Investigation of biomarkers alterations after an acute tissue trauma in human trapezius muscle, using microdialysis. Scientific Reports 8:1.
Crossref
M. Ernberg, N. Christidis, B. Ghafouri, I. Bileviciute-Ljungar, M. Löfgren, J. Bjersing, A. Palstam, A. Larsson, K. Mannerkorpi, B. Gerdle & E. Kosek. (2018) Plasma Cytokine Levels in Fibromyalgia and Their Response to 15 Weeks of Progressive Resistance Exercise or Relaxation Therapy. Mediators of Inflammation 2018, pages 1-14.
Crossref
S. Louca Jounger, N. Christidis, P. Svensson, T. List & M. Ernberg. (2017) Increased levels of intramuscular cytokines in patients with jaw muscle pain. The Journal of Headache and Pain 18:1.
Crossref
Maria V. Turkina, Nazdar Ghafouri, Björn Gerdle & Bijar Ghafouri. (2017) Evaluation of dynamic changes in interstitial fluid proteome following microdialysis probe insertion trauma in trapezius muscle of healthy women. Scientific Reports 7:1.
Crossref
Leonardo Fierro. (2017) Serotonin-gated inward currents are three times more frequent in rat hairy skin sensory afferents than in those innervating the skeletal muscle. Molecular Pain 13, pages 174480691772905.
Crossref
Fereshteh Dardmeh, Hiva Alipour, Hans Ingolf Nielsen, Sten Rasmussen & Parisa Gazerani. (2017) Effects of Chronic Musculoskeletal Pain on Fertility Potential in Lean and Overweight Male Patients. Pain Research and Management 2017, pages 1-10.
Crossref
Bodil Ohlsson. 2019. Dysphagia. Dysphagia 149 155 .
Hajer Jasim, Patrik Olausson, Britt Hedenberg-Magnusson, Malin Ernberg & Bijar Ghafouri. (2016) The proteomic profile of whole and glandular saliva in healthy pain-free subjects. Scientific Reports 6:1.
Crossref
Malin Ernberg, Nikolaos Christidis, Bijar Ghafouri, Indre Bileviciute-Ljungar, Monika Löfgren, Anette Larsson, Annie Palstam, Jan Bjersing, Kaisa Mannerkorpi, Eva Kosek & Björn Gerdle. (2016) Effects of 15 weeks of resistance exercise on pro-inflammatory cytokine levels in the vastus lateralis muscle of patients with fibromyalgia. Arthritis Research & Therapy 18:1.
Crossref
Jeanette Reffstrup Christensen, Thomas Viskum Gjelstrup Bredahl, Jenny Hadrévi, Gisela Sjøgaard & Karen Søgaard. (2016) Background, design and conceptual model of the cluster randomized multiple-component workplace study: FRamed Intervention to Decrease Occupational Muscle pain - "FRIDOM". BMC Public Health 16:1.
Crossref
Björn Gerdle, Malin Ernberg, Kaisa Mannerkorpi, Britt Larsson, Eva Kosek, Nikolaos Christidis & Bijar Ghafouri. (2016) Increased Interstitial Concentrations of Glutamate and Pyruvate in Vastus Lateralis of Women with Fibromyalgia Syndrome Are Normalized after an Exercise Intervention – A Case-Control Study. PLOS ONE 11:10, pages e0162010.
Crossref
Yannick Van Wanseele, An De Prins, Dimitri De Bundel, Ilse Smolders & Ann Van Eeckhaut. (2016) Challenges for the in vivo quantification of brain neuropeptides using microdialysis sampling and LC–MS . Bioanalysis 8:18, pages 1965-1985.
Crossref
A. Grimby-Ekman, B. Ghafouri, H. Sandén, B. Larsson & B. Gerdle. (2016) Different DHEA-S Levels and Response Patterns in Individuals with Chronic Neck Pain, Compared with a Pain Free Group—a Pilot Study. Pain Medicine, pages pnw162.
Crossref
Hannah Gajsar, Christina Titze, Monika Ilona Hasenbring & Henrik Bjarke Vaegter. (2016) Isometric Back Exercise Has Different Effect on Pressure Pain Thresholds in Healthy Men and Women. Pain Medicine, pages pnw176.
Crossref
Francisco Caravaca, Boris Gonzales, Miguel Ángel Bayo & Enrique Luna. (2016) Musculoskeletal pain in patients with chronic kidney disease. Nefrología (English Edition) 36:4, pages 433-440.
Crossref
Francisco Caravaca, Boris Gonzales, Miguel Ángel Bayo & Enrique Luna. (2016) Dolor músculo-esquelético en pacientes con enfermedad renal crónica. Nefrología 36:4, pages 433-440.
Crossref
Hugh MacPhersonRichard HammerschlagRemy R. CoeytauxRobert T. DavisRichard E. HarrisJiang-Ti KongHelene M. LangevinLixing LaoRyan J. MilleyVitaly NapadowRosa N. SchnyerElisabet Stener-VictorinClaudia M. WittPeter M. Wayne. (2016) Unanticipated Insights into Biomedicine from the Study of Acupuncture. The Journal of Alternative and Complementary Medicine 22:2, pages 101-107.
Crossref
Nikolaos Christidis, Bijar Ghafouri, Anette Larsson, Annie Palstam, Kaisa Mannerkorpi, Indre Bileviciute-Ljungar, Monika Löfgren, Jan Bjersing, Eva Kosek, Björn Gerdle & Malin Ernberg. (2015) Comparison of the Levels of Pro-Inflammatory Cytokines Released in the Vastus Lateralis Muscle of Patients with Fibromyalgia and Healthy Controls during Contractions of the Quadriceps Muscle – A Microdialysis Study. PLOS ONE 10:12, pages e0143856.
Crossref
Mariana Moreira da Silva, Regiane Albertini, Ernesto Cesar Pinto Leal-Junior, Paulo de Tarso Camillo de Carvalho, José Antonio SilvaJrJr, Sandra Kalil Bussadori, Luis Vicente Franco de Oliveira, Cezar Augusto Souza Casarin, Erinaldo Luiz Andrade, Danilo Sales Bocalini & Andrey Jorge Serra. (2015) Effects of exercise training and photobiomodulation therapy (EXTRAPHOTO) on pain in women with fibromyalgia and temporomandibular disorder: study protocol for a randomized controlled trial. Trials 16:1.
Crossref
J. Hadrévi, M. Björklund, E. Kosek, S. Hällgren, H. Antti, M. Fahlström & F. Hellström. (2015) Systemic differences in serum metabolome: a cross sectional comparison of women with localised and widespread pain and controls. Scientific Reports 5:1.
Crossref
Enrique Lluch, Jo Nijs, Margot De Kooning, Dries Van Dyck, Rob Vanderstraeten, Filip Struyf & Nathalie Anne Roussel. (2015) Prevalence, Incidence, Localization, and Pathophysiology of Myofascial Trigger Points in Patients With Spinal Pain: A Systematic Literature Review. Journal of Manipulative and Physiological Therapeutics 38:8, pages 587-600.
Crossref
W. Michael Panneton, Qi Gan & Michael Ariel. (2015) Injections of Algesic Solutions into Muscle Activate the Lateral Reticular Formation: A Nociceptive Relay of the Spinoreticulothalamic Tract. PLOS ONE 10:7, pages e0130939.
Crossref
Bradford W Fenton, Elim Shih & Jessica Zolton. (2015) The neurobiology of pain perception in normal and persistent pain. Pain Management 5:4, pages 297-317.
Crossref
Sala Horowitz. (2015) Current Understanding of Fibromyalgia: Diagnosis, Treatment, and Theories About Causes. Alternative and Complementary Therapies 21:1, pages 25-31.
Crossref
Leonardo Ierardi Goulart, Raimundo Nonato Delgado Rodrigues & Mario Fernando Prieto Peres. (2014) Restless Legs Syndrome and Pain Disorders: What’s in common?. Current Pain and Headache Reports 18:11.
Crossref
Chien-Chung Huang & Chia-Shiang Lin. (2014) Ultrasound-guided chronic musculoskeletal pain control. Acta Anaesthesiologica Taiwanica 52:3, pages 93-94.
Crossref