494
Views
31
CrossRef citations to date
0
Altmetric
Review

Osimertinib in the treatment of non-small-cell lung cancer: design, development and place in therapy

, , , , , , , & show all
Pages 109-125 | Published online: 18 Aug 2017

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (7)

Chung-Shien Lee, Matthew Milone & Nagashree Seetharamu. (2021) Osimertinib in EGFR-Mutated Lung Cancer: A Review of the Existing and Emerging Clinical Data. OncoTargets and Therapy 14, pages 4579-4597.
Read now
Chung-Shien Lee, Sandhya Sharma, Emily Miao, Cheryl Mensah, Kevin Sullivan & Nagashree Seetharamu. (2020) A Comprehensive Review of Contemporary Literature for Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer and Their Toxicity. Lung Cancer: Targets and Therapy 11, pages 73-103.
Read now
Xuejuan Gao, Yanfeng Zhao, Yi Bao, Wei Yin, Liyu Liu, Ruchuan Liu, Zhengquan Yu, Xiao Zhou & Jianwei Shuai. (2019) Poor Prognosis With Coexistence Of EGFR T790M Mutation And Common EGFR-Activating Mutation In Non- Small Cell Lung Cancer. Cancer Management and Research 11, pages 9621-9630.
Read now
Mariacarmela Santarpia, Jessica Menis, Imane Chaib, Maria Gonzalez Cao & Rafael Rosell. (2019) Dacomitinib for the first-line treatment of patients with EGFR-mutated metastatic non-small cell lung cancer. Expert Review of Clinical Pharmacology 12:9, pages 831-840.
Read now
Jie Wang, XianYe Cheng, Yan Lu & BingRong Zhou. (2018) A case report of toxic epidermal necrolysis associated with AZD-9291. Drug Design, Development and Therapy 12, pages 2163-2167.
Read now
Ilaria Attili, Niki Karachaliou, PierFranco Conte, Laura Bonanno & Rafael Rosell. (2018) Therapeutic approaches for T790M mutation positive non-small-cell lung cancer. Expert Review of Anticancer Therapy 18:10, pages 1021-1030.
Read now
Mariacarmela Santarpia, Niccola Funel, Asif Ali & Elisa Giovannetti. (2018) Liquid biopsies to optimize therapeutic efficacy in unresponsive lung cancer patients. Expert Opinion on Drug Metabolism & Toxicology 14:8, pages 761-763.
Read now

Articles from other publishers (24)

Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Rui Manuel Reis & Letícia Ferro Leal. (2023) Liquid Biopsy for Lung Cancer: Up-to-Date and Perspectives for Screening Programs. International Journal of Molecular Sciences 24:3, pages 2505.
Crossref
Jang Ho Lee, Eun Young Kim, Cheol-Kyu Park, Shin Yup Lee, Min ki Lee, Seong-Hoon Yoon, Jeong Eun Lee, Sang Hoon Lee, Seung Joon Kim, Sung Yong Lee, Jun Hyeok Lim, Tae-Won Jang, Seung Hun Jang, Kye Young Lee, Seung Hyeun Lee, Sei Hoon Yang, Dong Won Park, Chan Kwon Park, Hye Seon Kang, Chang Dong Yeo, Chang-Min Choi & Jae Cheol Lee. (2023) Real-World Study of Osimertinib in Korean Patients with Epidermal Growth Factor Receptor T790M Mutation–Positive Non–Small Cell Lung Cancer. Cancer Research and Treatment 55:1, pages 112-122.
Crossref
Lovenish Bains & Tanuj Chawla. 2023. Gallbladder Cancer. Gallbladder Cancer 331 349 .
Mona A. Ibrahim, Sherif R. Mohamed, Mohamed A. Dkhil, Felwa A. Thagfan, Rewaida Abdel-Gaber & Doaa Soliman. (2022) The effect of Moringa oleifera leaf extracts against urethane-induced lung cancer in rat model. Environmental Science and Pollution Research 30:13, pages 37280-37294.
Crossref
Weiying Lin, Zhuoyi Lin & Mengxue Zhang. (2022) The Therapy of Osimertinib for EGFR Mutation—Non-small Cell Lung Cancer. Highlights in Science, Engineering and Technology 6, pages 219-229.
Crossref
Matin Shaikh, Yashodeep Shinde, Rahul Pawara, Malleshappa Noolvi, Sanjay Surana, Iqrar Ahmad & Harun Patel. (2021) Emerging Approaches to Overcome Acquired Drug Resistance Obstacles to Osimertinib in Non-Small-Cell Lung Cancer. Journal of Medicinal Chemistry 65:2, pages 1008-1046.
Crossref
燕 钟. (2022) Correlation between the Expression of PDCD4 and AP-1 and Cell Migration in Non-Small Cell Lung Cancer A549 and H520 Cells. Advances in Clinical Medicine 12:07, pages 6517-6524.
Crossref
Andrey D. Kaprin, S. A. Ivanov, V. A. Petrov, L. J. Grivtsova & Karine Sargsyan. 2022. Biobanks in Low- and Middle-Income Countries: Relevance, Setup and Management. Biobanks in Low- and Middle-Income Countries: Relevance, Setup and Management 175 192 .
Bengisu Dayanc, Sude Eris & Serif Senturk. 2022.
Zhongwei Liu, Neal Shah, Kent L. Marshall, Samuel A. Sprowls, Pushkar Saralkar, Afroz Mohammad, Kathryn E. Blethen, Tasneem A. Arsiwala, Ross Fladeland, Paul R. Lockman & Weimin Gao. (2021) Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo. Archives of Toxicology 95:11, pages 3575-3587.
Crossref
Yun-ting Zhu, Yi-fan Zhang, Jin-fang Jiang, Yong Yang, Li-xia Guo, Jing-jing Bao & Da-fang Zhong. (2021) Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers. Investigational New Drugs 39:4, pages 1011-1018.
Crossref
Mohd. Imran, Syed Mohammed Basheeruddin Asdaq, Shah Alam Khan, Dhanalekshmi Unnikrishnan Meenakshi, Abdulhakeem S. Alamri, Walaa F. Alsanie, Majid Alhomrani, Yahya Mohzari, Ahmed Alrashed, Mohammed AlMotairi, Eman H. Alkhaldi, Abeer K. Alorabi, Ahmed Subeh Alshrari, Mohammad Tauseef, Abida, Saleh I. Alaqel, Ozair Alam & Md. Afroz Bakht. (2021) Innovations and Patent Trends in the Development of USFDA Approved Protein Kinase Inhibitors in the Last Two Decades. Pharmaceuticals 14:8, pages 710.
Crossref
Shuo Li, Linping Ke, Xue Meng, Haiyan Zhou, Xiqin Zhang, Huaguo Wu, Jinming Yu & Hui Zhang. (2021) Next Generation Sequencing in the Management of Leptomeningeal Metastases of Non-Small Cell Lung Cancer: A Case Report and Literature Review. Recent Patents on Anti-Cancer Drug Discovery 16:1, pages 108-116.
Crossref
Christiane Stiller, Kristina Viktorsson, Elizabeth Paz Gomero, Petra Hååg, Vasiliki Arapi, Vitaliy O. Kaminskyy, Caroline Kamali, Luigi De Petris, Simon Ekman, Rolf Lewensohn & Amelie Eriksson Karlström. (2021) Detection of Tumor-Associated Membrane Receptors on Extracellular Vesicles from Non-Small Cell Lung Cancer Patients via Immuno-PCR. Cancers 13:4, pages 922.
Crossref
Remco de Kock, Chantal Knoops, Mieke Baselmans, Ben van den Borne, Luc Brunsveld, Volkher Scharnhorst & Birgit Deiman. (2021) Sensitive cell-free tumor DNA analysis in supernatant pleural effusions supports therapy selection and disease monitoring of lung cancer patients. Cancer Treatment and Research Communications 29, pages 100449.
Crossref
Jing Cong, Yuguang Zhang, Yadong Xue, Chuantao Zhang, Mingjin Xu, Dong Liu, Ruiyan Zhang & Hua Zhu. (2020) A Pilot Study: Changes of Intestinal Microbiota of Patients With Non-small Cell Lung Cancer in Response to Osimertinib Therapy. Frontiers in Microbiology 11.
Crossref
Juliana F. Vilachã, Sarah C. Mitchel, Muluembet Z. Akele, Stephen Evans & Matthew R. Groves. (2020) Making NSCLC Crystal Clear: How Kinase Structures Revolutionized Lung Cancer Treatment. Crystals 10:9, pages 725.
Crossref
E. V. Reutova, K. K. Laktionov, D. I. Yudin & M. S. Ardzinba. (2019) Rational approach to the treatment of EGFR-positive lung cancer. Medical Council:19, pages 51-56.
Crossref
David M. Evans, Jianwen Fang, Thomas Silvers, Rene Delosh, Julie Laudeman, Chad Ogle, Russell Reinhart, Michael Selby, Lori Bowles, John Connelly, Erik Harris, Julia Krushkal, Larry Rubinstein, James H. Doroshow & Beverly A. Teicher. (2019) Exposure time versus cytotoxicity for anticancer agents. Cancer Chemotherapy and Pharmacology 84:2, pages 359-371.
Crossref
Yi-Lin Chen, Chien-Chung Lin, Shu-Ching Yang, Wan-Li Chen, Jian-Rong Chen, Yi-Hsin Hou, Cheng-Chan Lu, Nan-Haw Chow, Wu-Chou Su & Chung-Liang Ho. (2019) Five Technologies for Detecting the EGFR T790M Mutation in the Circulating Cell-Free DNA of Patients With Non-small Cell Lung Cancer: A Comparison. Frontiers in Oncology 9.
Crossref
Hope S. Rugo, Jack A. Di Palma, Debu Tripathy, Richard Bryce, Susan Moran, Elizabeth Olek & Linda Bosserman. (2019) The characterization, management, and future considerations for ErbB-family TKI-associated diarrhea. Breast Cancer Research and Treatment 175:1, pages 5-15.
Crossref
Eduardo Clery, Pasquale Pisapia, Elena Vigliar, Umberto Malapelle, Claudio Bellevicine, Giancarlo Troncone & Fernando C. Schmitt. (2019) Role of Cytomorphology in the Era of Liquid Biopsy. Acta Cytologica 63:6, pages 497-505.
Crossref
Simon Garinet, Pierre Laurent-Puig, Hélène Blons & Jean-Baptiste Oudart. (2018) Current and Future Molecular Testing in NSCLC, What Can We Expect from New Sequencing Technologies?. Journal of Clinical Medicine 7:6, pages 144.
Crossref
Arenda D. Meedendorp, Arja ter Elst, Nils A. ’t Hart, Harry J. M. Groen, Ed Schuuring & Anthonie J. van der Wekken. (2018) Response to HER2 Inhibition in a Patient With Brain Metastasis With EGFR TKI Acquired Resistance and an HER2 Amplification. Frontiers in Oncology 8.
Crossref