TKI-resistant ALK-rearranged lung adenocarcinoma with secondary CTNNB1 p.S45V and tertiary ALK p.I1171N mutations

Madhu M Ouseph1 Department of Pathology, Rhode Island Hospital and Alpert Medical School at Brown University, Providence, RI02903, USA

Angela Taber2 Division of Medical Oncology, Miriam Hospital and Alpert Medical School at Brown University, Providence, RI02906, USA

Humera Khurshid3 Division of Medical Oncology, Rhode Island Hospital and Alpert Medical School at Brown University, Providence, RI02903, USA

Russell Madison4 Foundation Medicine, Inc ., Cambridge, MA02141, USA

Bassam I Aswad1 Department of Pathology, Rhode Island Hospital and Alpert Medical School at Brown University, Providence, RI02903, USA

Murray B Resnick1 Department of Pathology, Rhode Island Hospital and Alpert Medical School at Brown University, Providence, RI02903, USA

Evgeny Yakirevich1 Department of Pathology, Rhode Island Hospital and Alpert Medical School at Brown University, Providence, RI02903, USA

Siraj M Ali4 Foundation Medicine, Inc ., Cambridge, MA02141, USA

Nimesh R Patel1 Department of Pathology, Rhode Island Hospital and Alpert Medical School at Brown University, Providence, RI02903, USACorrespondence[email protected]

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TKI-resistant ALK-rearranged lung adenocarcinoma with secondary CTNNB1 p.S45V and tertiary ALK p.I1171N mutations

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TKI-resistant ALK-rearranged lung adenocarcinoma with secondary CTNNB1 p.S45V and tertiary ALK p.I1171N mutations

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