Advanced search
Publication Cover
Neuropsychiatric Disease and Treatment Volume 6, 2010 - Issue
Submit an article Journal homepage
69
Views
9
CrossRef citations to date
0
Altmetric
Original Research

Not all partial dopamine D2 receptor agonists are the same in treating schizophrenia. Exploring the effects of bifeprunox and aripiprazole using a computer model of a primate striatal dopaminergic synapse

Athan Spiros1 In Silico Biosciences, Berwyn, PA, USA
,
Robert Carr1 In Silico Biosciences, Berwyn, PA, USA
&
Hugo Geerts1 In Silico Biosciences, Berwyn, PA, USA;2 School of Medicine, University of Pennsylvania, PA, USACorrespondence[email protected]
Pages 589-603 | Published online: 06 Sep 2010

Citations (9)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

Hugo Geerts, Athan Spiros & Patrick Roberts. (2017) Phosphodiesterase 10 inhibitors in clinical development for CNS disorders. Expert Review of Neurotherapeutics 17:6, pages 553-560.
Read now
Athan Spiros & Hugo Geerts. (2012) A quantitative way to estimate clinical off-target effects for human membrane brain targets in CNS research and development. Journal of Experimental Pharmacology 4, pages 53-61.
Read now

Articles from other publishers (7)

Rachel Rose, Emma Mitchell, Piet Van Der Graaf, Daisuke Takaichi, Jun Hosogi & Hugo Geerts. (2022) A quantitative systems pharmacology model for simulating OFF-Time in augmentation trials for Parkinson’s disease: application to preladenant. Journal of Pharmacokinetics and Pharmacodynamics 49:6, pages 593-606.
Crossref
Patrick D. Roberts & James Conour. (2022) Mechanistic modeling as an explanatory tool for clinical treatment of chronic catatonia. Frontiers in Pharmacology 13.
Crossref
Athan Spiros & Hugo Geerts. (2021) Toward Predicting Impact of Common Genetic Variants on Schizophrenia Clinical Responses With Antipsychotics: A Quantitative System Pharmacology Study. Frontiers in Neuroscience 15.
Crossref
Hugo Geerts & James E. Barrett. (2019) Neuronal Circuit-Based Computer Modeling as a Phenotypic Strategy for CNS R&D. Frontiers in Neuroscience 13.
Crossref
Patrick Roberts, Athan Spiros & Hugo Geerts. (2016) A Humanized Clinically Calibrated Quantitative Systems Pharmacology Model for Hypokinetic Motor Symptoms in Parkinson’s Disease. Frontiers in Pharmacology 7.
Crossref
Hugo Geerts, Patrick Roberts & Athan Spiros. (2015) Assessing the synergy between cholinomimetics and memantine as augmentation therapy in cognitive impairment in schizophrenia. A virtual human patient trial using quantitative systems pharmacology. Frontiers in Pharmacology 6.
Crossref
Athan Spiros, Patrick Roberts & Hugo Geerts. (2014) A computer-based quantitative systems pharmacology model of negative symptoms in schizophrenia: exploring glycine modulation of excitation-inhibition balance. Frontiers in Pharmacology 5.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.