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Neuropsychiatric Disease and Treatment Volume 13, 2017 - Issue

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Original Research

Influence of CFH gene on symptom severity of schizophrenia

Chen Zhang1 Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, ShanghaiCorrespondence[email protected] [email protected]

Qinyu Lv1 Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai

Weixing Fan2 Department of Psychiatry, Jinhua Second Hospital, Jinhua

Wei Tang3 Department of Psychiatry, Wenzhou Kanging Hospital, Wenzhou, People’s Republic of China

Zhenghui Yi1 Schizophrenia Program, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, ShanghaiCorrespondence[email protected] [email protected]

Pages 697-706 | Published online: 02 Mar 2017

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Leanna M. Hernandez, Minsoo Kim, Pan Zhang, Richard A. I. Bethlehem, Gil Hoftman, Robert Loughnan, Diana Smith, Susan Y. Bookheimer, Chun Chieh Fan, Carrie E. Bearden, Wesley K. Thompson & Michael J. Gandal. (2023) Multi-ancestry phenome-wide association of complement component 4 variation with psychiatric and brain phenotypes in youth. Genome Biology 24:1.
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Kevin S. O'Connell, Ida E. Sønderby, Oleksandr Frei, Dennis van der Meer, Lavinia Athanasiu, Olav B. Smeland, Dag Alnæs, Tobias Kaufmann, Lars T. Westlye, Vidar M. Steen, Ole A. Andreassen, Timothy Hughes & Srdjan Djurovic. (2021) Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank. Psychological Medicine 52:15, pages 3497-3507.
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Hua Yu, Peiyan Ni, Yang Tian, Liansheng Zhao, Mingli Li, Xiaojing Li, Wei Wei, Jinxue Wei, Xiangdong Du, Qiang Wang, Wanjun Guo, Wei Deng, Xiaohong Ma, Jeremy Coid & Tao Li. (2022) Association of the plasma complement system with brain volume deficits in bipolar and major depressive disorders. Psychological Medicine, pages 1-11.
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Nikolai Tschernoster, Florian Erger, Patrick R. Walsh, Bairbre McNicholas, Margareta Fistrek, Sandra Habbig, Anna-Lena Schumacher, Kat Folz-Donahue, Christian Kukat, Mohammad R. Toliat, Christian Becker, Holger Thiele, David Kavanagh, Peter Nürnberg, Bodo B. Beck & Janine Altmüller. (2022) Unraveling Structural Rearrangements of the CFH Gene Cluster in Atypical Hemolytic Uremic Syndrome Patients Using Molecular Combing and Long-Fragment Targeted Sequencing. The Journal of Molecular Diagnostics 24:6, pages 619-631.
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Sizhong Guan, Linge Jian, Ye He, Yanna Su & Liping Zhou. (2022) Bioinformatic identification of differentially expressed genes regulated by DNA‐methylation in glioblastoma. European Journal of Neuroscience 55:5, pages 1278-1290.
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Ruimei Liu, Wei Tang, Weiping Wang, Feikang Xu, Weixing Fan, Yi Zhang & Chen Zhang. (2021) NLRP3 Influences Cognitive Function in Schizophrenia in Han Chinese. Frontiers in Genetics 12.
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Emma Corley, Laurena Holleran, Laura Fahey, Aiden Corvin, Derek W. Morris & Gary Donohoe. (2021) Microglial-expressed genetic risk variants, cognitive function and brain volume in patients with schizophrenia and healthy controls. Translational Psychiatry 11:1.
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Jessica F. Holland, Donna Cosgrove, Laura Whitton, Denise Harold, Aiden Corvin, Michael Gill, David O. Mothersill, Derek W. Morris & Gary Donohoe. (2020) Effects of complement gene‐set polygenic risk score on brain volume and cortical measures in patients with psychotic disorders and healthy controls. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 183:8, pages 445-453.
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Dandan Wang, Wei Tang, Junxiong Zhao, Weixing Fan, Yi Zhang & Chen Zhang. (2020) A Comprehensive Analysis of the Effect of SIRT1 Variation on the Risk of Schizophrenia and Depressive Symptoms. Frontiers in Genetics 11.
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Yi Zhang, Junxiong Zhao, Weiping Wang, Weixing Fan, Wei Tang & Chen Zhang. (2020) Homocysteine, but not MTHFR gene polymorphism, influences depressive symptoms in patients with schizophrenia. Journal of Affective Disorders 272, pages 24-27.
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Julia J. Woo, Jennie G. Pouget, Clement C. Zai & James L. Kennedy. (2019) The complement system in schizophrenia: where are we now and what’s next?. Molecular Psychiatry 25:1, pages 114-130.
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Jessica F. Holland, Donna Cosgrove, Laura Whitton, Denise Harold, Aiden Corvin, Michael Gill, David O. Mothersill, Derek W. Morris & Gary Donohoe. (2019) Beyond C4: Analysis of the complement gene pathway shows enrichment for IQ in patients with psychotic disorders and healthy controls. Genes, Brain and Behavior 18:8.
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John D. Lee, Liam G. Coulthard & Trent M. Woodruff. (2019) Complement dysregulation in the central nervous system during development and disease. Seminars in Immunology 45, pages 101340.
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Feikang Xu, Weixing Fan, Weiping Wang, Wei Tang, Fuyin Yang, Yi Zhang, Jun Cai, Lisheng Song & Chen Zhang. (2018) Effects of omega-3 fatty acids on metabolic syndrome in patients with schizophrenia: a 12-week randomized placebo-controlled trial. Psychopharmacology 236:4, pages 1273-1279.
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G. Donohoe, J. Holland, D. Mothersill, S. McCarthy-Jones, D. Cosgrove, D. Harold, A. Richards, K. Mantripragada, M. J. Owen, M. C. O'Donovan, M. Gill, A. Corvin & D. W. Morris. (2018) Genetically predicted complement component 4A expression: effects on memory function and middle temporal lobe activation. Psychological Medicine 48:10, pages 1608-1615.
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Liam G. Coulthard, Owen A. Hawksworth & Trent M. Woodruff. (2018) Complement: The Emerging Architect of the Developing Brain. Trends in Neurosciences 41:6, pages 373-384.
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Yi Zhang, Xinyu Fang, Weixing Fan, Wei Tang, Jun Cai, Lisheng Song & Chen Zhang. (2018) Interaction between BDNF and TNF-α genes in schizophrenia. Psychoneuroendocrinology 89, pages 1-6.
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Weihong Lu, Yi Zhang, Xinyu Fang, Weixing Fan, Wei Tang, Jun Cai, Lisheng Song & Chen Zhang. (2017) Genetic association analysis of microRNA137 and its target complex 1 with schizophrenia in Han Chinese. Scientific Reports 7:1.
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