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Neuropsychiatric Disease and Treatment Volume 14, 2018 - Issue
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Original Research

Dysfunction of cortical synapse-specific mitochondria in developing rats exposed to lead and its amelioration by ascorbate supplementation

Faraz Ahmad1 Department of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia;2 Neuroscience Department, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence[email protected]
,
Mohammad Salahuddin3 Animal House Department, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
,
Widyan Alamoudi2 Neuroscience Department, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
&
Sadananda Acharya1 Department of Public Health, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
Pages 813-824 | Published online: 21 Mar 2018

Citations (11)

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Faraz Ahmad, Mohammad Salahuddin, Khaldoon Alsamman, Abdulaziz A AlMulla & Khaled F Salama. (2018) Developmental lead (Pb)-induced deficits in hippocampal protein translation at the synapses are ameliorated by ascorbate supplementation. Neuropsychiatric Disease and Treatment 14, pages 3289-3298.
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Articles from other publishers (10)

Lakshmi Jaya Madhuri Bandaru, Lokesh Murumulla, Bindu Lasya C., Krishna Prasad D. & Suresh Challa. (2023) Exposure of combination of environmental pollutant, lead (Pb) and β-amyloid peptides causes mitochondrial dysfunction and oxidative stress in human neuronal cells. Journal of Bioenergetics and Biomembranes 55:1, pages 79-89.
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Rahul Tripathi, Rohan Gupta, Mehar Sahu, Devesh Srivastava, Ankita Das, Rashmi K Ambasta & Pravir Kumar. (2021) Free radical biology in neurological manifestations: mechanisms to therapeutics interventions. Environmental Science and Pollution Research 29:41, pages 62160-62207.
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Zai-Hua Zhao, Ke-Jun Du, Tao Wang, Ji-Ye Wang, Zi-Peng Cao, Xiao-Ming Chen, Han Song, Gang Zheng & Xue-Feng Shen. (2021) Maternal Lead Exposure Impairs Offspring Learning and Memory via Decreased GLUT4 Membrane Translocation. Frontiers in Cell and Developmental Biology 9.
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Qing Han, Wei Zhang, JingChong Guo, Qian Zhu, Hui Chen, YongLi Xia & Gaochun Zhu. (2021) Mitochondrion: a sensitive target for Pb exposure. The Journal of Toxicological Sciences 46:8, pages 345-358.
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Miriam Beatriz Virgolini & Michael Aschner. 2021. Neurotoxicity of Metals: Old Issues and New Developments. Neurotoxicity of Metals: Old Issues and New Developments 159 213 .
Faraz Ahmad & Ping Liu. (2020) (Ascorb)ing Pb Neurotoxicity in the Developing Brain. Antioxidants 9:12, pages 1311.
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Faraz Ahmad & Ping Liu. (2020) Synaptosome as a tool in Alzheimer’s disease research. Brain Research 1746, pages 147009.
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Faraz Ahmad, Shafiul Haque, Vijaya Ravinayagam, Aqeel Ahmad, Majid Rasool Kamli, George E. Barreto & Ghulam Md Ashraf. (2020) Developmental lead (Pb)-induced deficits in redox and bioenergetic status of cerebellar synapses are ameliorated by ascorbate supplementation. Toxicology 440, pages 152492.
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Karina Chibowska, Jan Korbecki, Izabela Gutowska, Emilia Metryka, Maciej Tarnowski, Marta Goschorska, Katarzyna Barczak, Dariusz Chlubek & Irena Baranowska-Bosiacka. (2020) Pre- and Neonatal Exposure to Lead (Pb) Induces Neuroinflammation in the Forebrain Cortex, Hippocampus and Cerebellum of Rat Pups. International Journal of Molecular Sciences 21:3, pages 1083.
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Gerardo Hernández, Carla-Angélica Villanueva-Ibarra, María Maldonado-Vega, Nadia-Cristina López-Vanegas, Claudia-Estefania Ruiz-Cascante & José-Víctor Calderón-Salinas. (2019) Participation of phospholipase-A2 and sphingomyelinase in the molecular pathways to eryptosis induced by oxidative stress in lead-exposed workers. Toxicology and Applied Pharmacology 371, pages 12-19.
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