136
Views
29
CrossRef citations to date
0
Altmetric
Review

The direct and indirect effects of α-synuclein on microtubule stability in the pathogenesis of Parkinson’s disease

, &
Pages 1685-1695 | Published online: 27 Jun 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (1)

Shanshan Hu, Meigui Hu, Jian Liu, Bei Zhang, Zhen Zhang, Fiona H Zhou, Liping Wang & Jianghui Dong. (2020) Phosphorylation of Tau and α-Synuclein Induced Neurodegeneration in MPTP Mouse Model of Parkinson’s Disease. Neuropsychiatric Disease and Treatment 16, pages 651-663.
Read now

Articles from other publishers (28)

Yinan Duan, Yixuan Wang, Yonghong Liu, Zhaohui Jin, Cui Liu, Xin Yu, Keke Chen, Detao Meng, Jianing Xi & Boyan Fang. (2023) Circular RNAs in Parkinson’s Disease: Reliable Biological Markers and Targets for Rehabilitation. Molecular Neurobiology 60:6, pages 3261-3276.
Crossref
Suzhen Lin, André D.G. Leitão, Savannah Fang, Yingli Gu, Sophia Barber, Rhiannon Gilliard-Telefoni, Alfredo Castro, Kijung Sung, Ruinan Shen, Jazmin B. Florio, Michael L. Mante, Jianqing Ding, Brian Spencer, Eliezer Masliah, Robert A. Rissman & Chengbiao Wu. (2023) Overexpression of alpha synuclein disrupts APP and Endolysosomal axonal trafficking in a mouse model of synucleinopathy. Neurobiology of Disease 178, pages 106010.
Crossref
Tagan A. Griffin, Paul D. Schnier, Elisa M. Cleveland, Robert W. Newberry, Julia Becker & George A. Carlson. (2023) Fibril treatment changes protein interactions of tau and α-synuclein in human neurons. Journal of Biological Chemistry 299:3, pages 102888.
Crossref
Jessica K. Smith, George D. Mellick & Alex M. Sykes. (2023) The role of the endolysosomal pathway in α-synuclein pathogenesis in Parkinson’s disease. Frontiers in Cellular Neuroscience 16.
Crossref
Samanta Mazzetti, Alessandra M. Calogero, Gianni Pezzoli & Graziella Cappelletti. (2023) Cross-talk between α-synuclein and the microtubule cytoskeleton in neurodegeneration. Experimental Neurology 359, pages 114251.
Crossref
Estibaliz Santiago-Mujika, Ruth Luthi-Carter, Flaviano Giorgini & Elizabeta B. Mukaetova-Ladinska. (2022) Tubulin Isotypes and Posttranslational Modifications in Vascular Dementia and Alzheimer’s Disease. Journal of Alzheimer's Disease Reports 6:1, pages 739-748.
Crossref
Katharina Pieger, Verena Schmitt, Carina Gauer, Nadja Gießl, Iryna Prots, Beate Winner, Jürgen Winkler, Johann Helmut Brandstätter & Wei Xiang. (2022) Translocation of Distinct Alpha Synuclein Species from the Nucleus to Neuronal Processes during Neuronal Differentiation. Biomolecules 12:8, pages 1108.
Crossref
Judit Oláh, Attila Lehotzky, Tibor Szénási & Judit Ovádi. 2022. Dementia in Parkinson’s Disease - Everything you Need to Know. Dementia in Parkinson’s Disease - Everything you Need to Know.
Lukas Seebauer, Yanni Schneider, Alice Drobny, Sonja Plötz, Tomas Koudelka, Andreas Tholey, Iryna Prots, Beate Winner, Friederike Zunke, Jürgen Winkler & Wei Xiang. (2022) Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson’s Patient-Derived Neuronal Cells. International Journal of Molecular Sciences 23:3, pages 1812.
Crossref
Béatrice Chambraud, Cillian Byrne, Geri Meduri, Etienne Emile Baulieu & Julien Giustiniani. (2022) FKBP52 in Neuronal Signaling and Neurodegenerative Diseases: A Microtubule Story. International Journal of Molecular Sciences 23:3, pages 1738.
Crossref
Iris N. Serratos, Elizabeth Hernández-Pérez, Carolina Campos, Michael Aschner & Abel Santamaría. (2021) An Update on the Critical Role of α-Synuclein in Parkinson’s Disease and Other Synucleinopathies: from Tissue to Cellular and Molecular Levels. Molecular Neurobiology 59:1, pages 620-642.
Crossref
Kedong Guo, Yingbo Zhang, Libo Li, Jingyan Zhang, Hua Rong, Deshui Liu, Junping Wang, Ming Jin, Nan Luo & Xiaojie Zhang. (2021) Neuroprotective effect of paeoniflorin in the mouse model of Parkinson’s disease through α-synuclein/protein kinase C δ subtype signaling pathway. NeuroReport 32:17, pages 1379-1387.
Crossref
Estibaliz Santiago-Mujika, Ruth Luthi-Carter, Flaviano Giorgini, Raj N. Kalaria & Elizabeta B. Mukaetova-Ladinska. (2021) Tubulin and Tubulin Posttranslational Modifications in Alzheimer’s Disease and Vascular Dementia. Frontiers in Aging Neuroscience 13.
Crossref
Alida Amadeo, Sara Pizzi, Alessandro Comincini, Debora Modena, Alessandra Maria Calogero, Laura Madaschi, Gaia Faustini, Chiara Rolando, Arianna Bellucci, Gianni Pezzoli, Samanta Mazzetti & Graziella Cappelletti. (2021) The Association between α-Synuclein and α-Tubulin in Brain Synapses. International Journal of Molecular Sciences 22:17, pages 9153.
Crossref
Jara M. Baena-Montes, Sahar Avazzadeh & Leo R. Quinlan. (2021) α-synuclein pathogenesis in hiPSC models of Parkinson’s disease. Neuronal Signaling 5:2.
Crossref
Sahar Avazzadeh, Jara Maria Baena, Cameron Keighron, Yajaira Feller-Sanchez & Leo R. Quinlan. (2021) Modelling Parkinson’s Disease: iPSCs towards Better Understanding of Human Pathology. Brain Sciences 11:3, pages 373.
Crossref
Caroline Cristiano Real, Cláudia Kimie Suemoto, Karina Henrique Binda, Lea Tenenholz Grinberg, Carlos Augusto Pasqualucci, Wilson Jacob Filho, Renata Eloah de Lucena Ferretti-Rebustini, Ricardo Nitrini, Renata Elaine Paraizo Leite & Luiz Roberto de Britto. (2021) Active lifestyle enhances protein expression profile in subjects with Lewy body pathology. Dementia & Neuropsychologia 15:1, pages 41-50.
Crossref
Fares Bassil, Emily S. Meymand, Hannah J. Brown, Hong Xu, Timothy O. Cox, Shankar Pattabhiraman, Chantal M. Maghames, Qihui Wu, Bin Zhang, John Q. Trojanowski & Virginia M.-Y. Lee. (2021) α-Synuclein modulates tau spreading in mouse brains. Journal of Experimental Medicine 218:1.
Crossref
Emelie E. Aspholm, Irena Matečko-Burmann & Björn M. Burmann. (2020) Keeping α-Synuclein at Bay: A More Active Role of Molecular Chaperones in Preventing Mitochondrial Interactions and Transition to Pathological States?. Life 10:11, pages 289.
Crossref
Antonella Sferra, Francesco Nicita & Enrico Bertini. (2020) Microtubule Dysfunction: A Common Feature of Neurodegenerative Diseases. International Journal of Molecular Sciences 21:19, pages 7354.
Crossref
Marina I. Oliveira da Silva & Márcia A. Liz. (2020) Linking Alpha-Synuclein to the Actin Cytoskeleton: Consequences to Neuronal Function. Frontiers in Cell and Developmental Biology 8.
Crossref
Wenting Guo, Katarina Stoklund Dittlau & Ludo Van Den Bosch. (2020) Axonal transport defects and neurodegeneration: Molecular mechanisms and therapeutic implications. Seminars in Cell & Developmental Biology 99, pages 133-150.
Crossref
Judit Oláh, Attila Lehotzky, Sándor Szunyogh, Tibor Szénási, Ferenc Orosz & Judit Ovádi. (2020) Microtubule-Associated Proteins with Regulatory Functions by Day and Pathological Potency at Night. Cells 9:2, pages 357.
Crossref
Ping Chen & Xiaodong Li. (2019) Study on Effect of Striatal mGluR2/3 in Alleviating Motor Dysfunction in Rat PD Model Treated by Exercise Therapy. Frontiers in Aging Neuroscience 11.
Crossref
Alessandra M. Calogero, Samanta Mazzetti, Gianni Pezzoli & Graziella Cappelletti. (2019) Neuronal microtubules and proteins linked to Parkinson’s disease: a relevant interaction?. Biological Chemistry 400:9, pages 1099-1112.
Crossref
Peter Riederer, Daniela Berg, Nicolas Casadei, Fubo Cheng, Joseph Classen, Christian Dresel, Wolfgang Jost, Rejko Krüger, Thomas Müller, Heinz Reichmann, Olaf Rieß, Alexander Storch, Sabrina Strobel, Thilo van Eimeren, Hans-Ullrich Völker, Jürgen Winkler, Konstanze F. Winklhofer, Ullrich Wüllner, Friederike Zunke & Camelia-Maria Monoranu. (2019) α-Synuclein in Parkinson’s disease: causal or bystander?. Journal of Neural Transmission 126:7, pages 815-840.
Crossref
Judit Oláh & Judit Ovádi. (2019) Pharmacological targeting of α‐synuclein and TPPP /p25 in Parkinson's disease: challenges and opportunities in a Nutshell . FEBS Letters 593:13, pages 1641-1653.
Crossref
Francesca Longhena, Gaia Faustini, Maria Grazia Spillantini & Arianna Bellucci. (2019) Living in Promiscuity: The Multiple Partners of Alpha-Synuclein at the Synapse in Physiology and Pathology. International Journal of Molecular Sciences 20:1, pages 141.
Crossref