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Neuropsychiatric Disease and Treatment Volume 14, 2018 - Issue

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Original Research

Association study between COMT, DRD2, and DRD3 gene variants and antipsychotic treatment response in Mexican patients with schizophrenia

Raul Escamilla1 Schizophrenia Clinic, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (INPRFM), Mexico City, Mexico

Beatriz Camarena2 Department of Pharmacogenetics, INPRFM, Mexico City, Mexico, [email protected]Correspondence[email protected]

Ricardo Saracco-Alvarez1 Schizophrenia Clinic, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (INPRFM), Mexico City, Mexico

Ana Fresán3 Division of Clinical Research, INPRFM, Mexico City, Mexico

Sandra Hernández2 Department of Pharmacogenetics, INPRFM, Mexico City, Mexico, [email protected]

Alejandro Aguilar-García2 Department of Pharmacogenetics, INPRFM, Mexico City, Mexico, [email protected]

Pages 2981-2987 | Published online: 05 Nov 2018

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Rachel L. Moster. (2023) Ethnic Differences in Antipsychotic Response: What Genetic Variation Does and Does Not Tell Us. Current Behavioral Neuroscience Reports.
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Felice Iasevoli, Camilla Avagliano, Luigi D’Ambrosio, Annarita Barone, Mariateresa Ciccarelli, Giuseppe De Simone, Benedetta Mazza, Licia Vellucci & Andrea de Bartolomeis. (2023) Dopamine Dynamics and Neurobiology of Non-Response to Antipsychotics, Relevance for Treatment Resistant Schizophrenia: A Systematic Review and Critical Appraisal. Biomedicines 11:3, pages 895.
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Jiangbo Ying, Qian Hui Chew, Roger S. McIntyre & Kang Sim. (2023) Treatment-Resistant Schizophrenia, Clozapine Resistance, Genetic Associations, and Implications for Precision Psychiatry: A Scoping Review. Genes 14:3, pages 689.
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Abdolhakim Ghanbarzehi, Ali Sepehrinezhad, Nazanin Hashemi, Minoo Karimi & Ali Shahbazi. (2023) Disclosing common biological signatures and predicting new therapeutic targets in schizophrenia and obsessive–compulsive disorder by integrated bioinformatics analysis. BMC Psychiatry 23:1.
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Shimeng Jiao, Ting Cao & Hualin Cai. (2022) Peripheral biomarkers of treatment-resistant schizophrenia: Genetic, inflammation and stress perspectives. Frontiers in Pharmacology 13.
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Martin Harrow, Thomas H Jobe & Liping Tong. (2021) Twenty-year effects of antipsychotics in schizophrenia and affective psychotic disorders. Psychological Medicine 52:13, pages 2681-2691.
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Ingrid Fricke-Galindo, Blanca E. Pérez-Aldana, Luis R. Macías-Kauffer, Susana González-Arredondo, David Dávila-Ortiz de Montellano, Carlos L. Aviña-Cervantes, Marisol López-López, Yaneth Rodríguez-Agudelo & Nancy Monroy-Jaramillo. (2022) Impact of COMT, PRODH and DISC1 Genetic Variants on Cognitive Performance of Patients with Schizophrenia. Archives of Medical Research 53:4, pages 388-398.
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Evangelia Eirini Tsermpini, Tea Terzi, Blanka Kores Plesničar & Vita Dolžan. 2022. Psychiatric Genomics. Psychiatric Genomics 161 188 .

Dorota Frydecka, Błażej Misiak, Patryk Piotrowski, Tomasz Bielawski, Edyta Pawlak, Ewa Kłosińska, Maja Krefft, Kamila Al Noaimy, Joanna Rymaszewska, Ahmed A. Moustafa & Jarosław Drapała. (2021) The Role of Dopaminergic Genes in Probabilistic Reinforcement Learning in Schizophrenia Spectrum Disorders. Brain Sciences 12:1, pages 7.
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Kengo Oishi, Tomihisa Niitsu, Nobuhisa Kanahara, Yasunori Sato, Yoshimi Iwayama, Tomoko Toyota, Tasuku Hashimoto, Tsuyoshi Sasaki, Masayuki Takase, Akihiro Shiina, Takeo Yoshikawa & Masaomi Iyo. (2020) Genetic risks of schizophrenia identified in a matched case–control study. European Archives of Psychiatry and Clinical Neuroscience 271:4, pages 775-781.
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Maria J. Arranz, Juliana Salazar & Marta H. Hernández. (2021) Pharmacogenetics of antipsychotics: Clinical utility and implementation. Behavioural Brain Research 401, pages 113058.
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Dmitriy V. Ivashchenko, Sofi Z. Khoang, Bakhu V. Makhmudova, Nina I. Buromskaya, Pavel V. Shimanov, Roman V. Deitch, Kristina A. Akmalova, Grigoriy N. Shuev, Irina V. Dorina, Marina I. Nastovich, Eugenia N. Shagovenko, Elena A. Grishina, Lyudmila M. Savchenko, Yuriy S. Shevchenko & Dmitriy A. Sychev. (2020) Pharmacogenetics of antipsychotics in adolescents with acute psychotic episode during first 14 days after admission: effectiveness and safety evaluation. Drug Metabolism and Drug Interactions 35:4.
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D. V. Ivashchenko, S. Z. Khoang, M. Kh. Tazagulova, B. V. Makhmudova, N. I. Buromskaya, P. V. Shimanov, R. V. Deitch, I. V. Dorina, M. I. Nastovich, K. A. Akmalova, A. A. Kachanova, E. A. Grishina, L. M. Savchenko, Yu. S. Shevchenko & D. A. Sychev. (2020) The polymorphic variants DRD2 rs1800497 and ABCB1 3435C>T are associated with antipsychotic safety parameters in adolescents with an acute psychotic episode: the results of a pilot study. Neurology, Neuropsychiatry, Psychosomatics 12:5, pages 24-31.
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Matea Nikolac Perkovic, Marina Sagud, Maja Zivkovic, Suzana Uzun, Gordana Nedic Erjavec, Oliver Kozumplik, Dubravka Svob Strac, Ninoslav Mimica, Alma Mihaljevic Peles & Nela Pivac. (2020) Catechol-O-methyltransferase rs4680 and rs4818 haplotype association with treatment response to olanzapine in patients with schizophrenia. Scientific Reports 10:1.
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M. N. Grunina, A. M. Zabotina, A. S. Zhuravlev, M. M. Pchelina, E. V. Volkova, R. F. Nasyrova, A. E. Taraskina & E. M. Krupitsky. (2020) DOPAMINE RECEPTOR D2 (DRD2) IN PERIPHERAL BLOOD LYMPHOCYTES AS BIOMARKER OF RESPONSE TO ANTIPSYCHOTIC MEDICATION. The Scientific Notes of the Pavlov University 27:1, pages 45-56.
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Anna Morozova, Yana Zorkina, Konstantin Pavlov, Olga Pavlova, Zinaida Storozheva, Eugene Zubkov, Natalia Zakharova, Olga Karpenko, Alexander Reznik, Vladimir Chekhonin & Georgiy Kostyuk. (2019) Association of rs4680 COMT, rs6280 DRD3, and rs7322347 5HT2A With Clinical Features of Youth-Onset Schizophrenia. Frontiers in Psychiatry 10.
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Aline Hajj, Sahar Obeid, Saria Sahyoun, Chadia Haddad, Jocelyne Azar, Lydia Rabbaa Khabbaz & Souheil Hallit. (2019) Clinical and Genetic Factors Associated with Resistance to Treatment in Patients with Schizophrenia: A Case-Control Study. International Journal of Molecular Sciences 20:19, pages 4753.
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Association study between COMT, DRD2, and DRD3 gene variants and antipsychotic treatment response in Mexican patients with schizophrenia

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Association study between COMT, DRD2, and DRD3 gene variants and antipsychotic treatment response in Mexican patients with schizophrenia

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