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Expert Opinion

The modern perspective for long-acting injectables antipsychotics in the patient-centered care of schizophrenia

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Pages 1045-1060 | Published online: 30 Apr 2019

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Joshua Barnett & Sofia Pappa. (2023) Switching from Monthly to Three-Monthly Long-Acting Injectable Paliperidone: A Survey on Subjective Satisfaction and Safety. Patient Preference and Adherence 17, pages 1603-1610.
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Ruth Milz, Carmela Benson, Karl Knight, Jose Antunes, Dean Najarian, Paola-Maria Lopez Rengel, Steven Wang, Ute Richarz, Srihari Gopal & John M Kane. (2023) The Effect of Longer Dosing Intervals for Long-Acting Injectable Antipsychotics on Outcomes in Schizophrenia. Neuropsychiatric Disease and Treatment 19, pages 531-545.
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S Kor Spoelstra, Jojanneke Bruins, Leonie Bais, Paul Seerden, Stynke Castelein & Henderikus Knegtering. (2022) One-Month versus Three-Month Formulation of Paliperidone Palmitate Treatment in Psychotic Disorders: Patients’, Relatives’, and Mental Health Professionals’ Perspectives. Patient Preference and Adherence 16, pages 615-624.
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Maryia Zhdanava, H Lynn Starr, Todor I Totev, Patrick Lefebvre, Aditi Shah, Kristy Sheng & Dominic Pilon. (2022) Impact of COVID-19 Pandemic on Prescribing of Long-Acting Injectable Antipsychotics for Schizophrenia: Results from a United States Prescriber Survey. Neuropsychiatric Disease and Treatment 18, pages 2003-2019.
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Francesco Pietrini, Lorenzo Tatini, Gabriele Santarelli, Dario Brugnolo, Marco Squillace, Bernardo Bozza, Andrea Ballerini, Valdo Ricca & Giulio D’Anna. (2021) Self- and caregiver-perceived disability, subjective well-being, quality of life and psychopathology improvement in long-acting antipsychotic treatments: a 2-year follow-up study. International Journal of Psychiatry in Clinical Practice 25:3, pages 307-315.
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Martin Lambert, Pedro Sanchez, Paul Bergmans, Srihari Gopal, Maju Mathews, Annette Wooller & Katalin Pungor. (2020) Effect of Paliperidone Palmitate 3-Month Formulation on Goal Attainment and Disability After 52 Weeks’ Treatment in Patients with Clinically Stable Schizophrenia. Neuropsychiatric Disease and Treatment 16, pages 3197-3208.
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Articles from other publishers (18)

Khadija Benallel, Wafaa Mansouri, Jalal Salim, Roukaya Benjelloun & Mohamed Kadiri. (2023) Prescribing habits of Moroccan psychiatrists toward patients with schizophrenia: about 72 practitioners. Middle East Current Psychiatry 30:1.
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Renato de Filippis, Filippo Antonio Staltari, Matteo Aloi, Elvira Anna Carbone, Marianna Rania, Laura Destefano, Luca Steardo Jr., Cristina Segura-Garcia & Pasquale De Fazio. (2023) Effectiveness of SGA-LAIs on Clinical, Cognitive, and Social Domains in Schizophrenia: Results from a Prospective Naturalistic Study. Brain Sciences 13:4, pages 577.
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Antonio Vita, Andrea Fagiolini, Giuseppe Maina, Claudio Mencacci, Edoardo Spina & Silvana Galderisi. (2023) Achieving long-term goals through early personalized management of schizophrenia: expert opinion on the role of a new fast-onset long-acting injectable antipsychotic. Annals of General Psychiatry 22:1.
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Ilaria Riboldi, Daniele Cavaleri, Chiara A Capogrosso, Cristina Crocamo, Francesco Bartoli & Giuseppe Carrà. (2022) Practical Guidance for the Use of Long-Acting Injectable Antipsychotics in the Treatment of Schizophrenia. Psychology Research and Behavior Management Volume 15, pages 3915-3929.
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Hannah A. Blair. (2022) Paliperidone palmitate intramuscular 6-monthly formulation in schizophrenia: a profile of its use. Drugs & Therapy Perspectives 38:8, pages 335-342.
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Lulu Lian, David D. Kim, Ric M. Procyshyn, Diane H. Fredrikson, Diana Cázares, William G. Honer & Alasdair M. Barr. (2021) Efficacy of long‐acting injectable versus oral antipsychotic drugs in early psychosis: A systematic review and meta‐analysis. Early Intervention in Psychiatry 16:6, pages 589-599.
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Rosaria Di Lorenzo, Anita Iorio, Margherita Pinelli, Federica Maria Magarini, Mattia Marchi, Andrea Sacchetti, Chiara Calogero, Gian Galeazzi, Paola Ferri, Sergio Rovesti & Alessandro Minarini. (2022) Effectiveness and Quality of Life with Paliperidone Palmitate 3-Monthly in Comparison with Other Long-Acting Drugs. Neuropsychiatric Disease and Treatment Volume 18, pages 829-846.
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Dean Najarian, Panna Sanga, Steven Wang, Pilar Lim, Arun Singh, Mary Jane Robertson, Kristin Cohen, Alain Schotte, Ruth Milz, Raja Venkatasubramanian, Huybrecht T’Jollyn, David P Walling, Silvana Galderisi & Srihari Gopal. (2022) A Randomized, Double-Blind, Multicenter, Noninferiority Study Comparing Paliperidone Palmitate 6-Month Versus the 3-Month Long-Acting Injectable in Patients With Schizophrenia. International Journal of Neuropsychopharmacology 25:3, pages 238-251.
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Azizah Attard, John Wakelam, Josephine Broyd, David Taylor & Jonathan Hafferty. (2022) Olanzapine long-acting injection, discontinuation rates and reasons for discontinuation: 10 years’ experience at a UK high-secure hospital. Therapeutic Advances in Psychopharmacology 12, pages 204512532211130.
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Katalin Pungor, Pedro Sanchez, Sofia Pappa, Jerome Attal, Karolina Leopold, Geertje Steegen, Antonio Vita, Carol Marsella, Caroline Verrijcken, Marjolein Lahaye & Annette Wooller. (2021) The Patient, Investigator, Nurse, Carer Questionnaire (PINC-Q): a cross-sectional, retrospective, non-interventional study exploring the impact of less frequent medication administration with paliperidone palmitate 3-monthly as maintenance treatment for schizophrenia. BMC Psychiatry 21:1.
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Giovanni Ostuzzi & Corrado Barbui. (2021) Expanding access to long-acting antipsychotics in low-income and middle-income countries. The Lancet Psychiatry 8:12, pages 1034-1035.
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John M. Kane, Joseph P. McEvoy, Christoph U. Correll & Pierre-Michel Llorca. (2021) Controversies Surrounding the Use of Long-Acting Injectable Antipsychotic Medications for the Treatment of Patients with Schizophrenia. CNS Drugs 35:11, pages 1189-1205.
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Giovanni OstuzziFederico BertoliniCinzia Del GiovaneFederico TedeschiChiara BovoChiara GastaldonMichela NoséFilippo OgheriDavide PapolaMarianna PurgatoGiulia TurriniChristoph U. CorrellCorrado Barbui. (2021) Maintenance Treatment With Long-Acting Injectable Antipsychotics for People With Nonaffective Psychoses: A Network Meta-Analysis. American Journal of Psychiatry 178:5, pages 424-436.
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Gerhard Gründer, Philipp Bauknecht, Stefan Klingberg, Karolina Leopold, Michael Paulzen, Stefanie Schell, Katarina Stengler & Stefan Leucht. (2020) Treatment Goals for Patients with Schizophrenia — A Narrative Review of Physician and Patient Perspectives. Pharmacopsychiatry 54:02, pages 53-59.
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Maryia Zhdanava, Dee Lin, Marie-Hélène Lafeuille, Isabelle Ghelerter, Laura Morrison, Patrick Lefebvre & Kruti Joshi. (2021) Antipsychotic Adherence, Resource Use, and Costs Before and After the Initiation of Once-monthly Paliperidone Palmitate Therapy Among Medicaid Beneficiaries With Prior Schizophrenia Relapse. Clinical Therapeutics 43:3, pages 535-548.
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Blanca Fernández-Abascal, Maria Recio-Barbero, Margarita Sáenz-Herrero & Rafael Segarra. (2021) Long-acting injectable aripiprazole in pregnant women with schizophrenia: a case-series report. Therapeutic Advances in Psychopharmacology 11, pages 204512532199127.
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Mary V. Seeman. (2019) The Gut Microbiome and Treatment-Resistance in Schizophrenia. Psychiatric Quarterly 91:1, pages 127-136.
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Hsiao-Fen Hsu, Chia-Chan Kao, Ti Lu, Jeremy C. Ying & Sheng-Yu Lee. (2019) Differences in the Effectiveness of Long-Acting Injection and Orally Administered Antipsychotics in Reducing Rehospitalization among Patients with Schizophrenia Receiving Home Care Services. Journal of Clinical Medicine 8:6, pages 823.
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