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Neuropsychiatric Disease and Treatment Volume 8, 2012 - Issue
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Original Research

Six-month treatment with atypical antipsychotic drugs decreased frontal-lobe levels of glutamate plus glutamine in early-stage first-episode schizophrenia

Naoki Goto1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Reiji Yoshimura1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, JapanCorrespondence[email protected]
,
Shingo Kakeda2 Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Joji Nishimura2 Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Junji Moriya2 Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Kenji Hayashi1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Asuka Katsuki1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Hikaru Hori1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Wakako Umene-Nakano1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Atsuko Ikenouchi-Sugita1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
,
Yukunori Korogi2 Department of Radiology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
&
Jun Nakamura1 Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan
 show all
Pages 119-122 | Published online: 03 Apr 2012

Citations (10)

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Read on this site (3)

Juan R. Bustillo. (2013) Use of proton magnetic resonance spectroscopy in the treatment of psychiatric disorders: a critical update. Dialogues in Clinical Neuroscience 15:3, pages 329-337.
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Roger M Pinder. (2012) Editor’s choice. Neuropsychiatric Disease and Treatment 8, pages 321-322.
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Roberto Lozano Ortiz. (2012) Influence of drug treatment with antidepressants and antipsychotics on plasma urea levels. Neuropsychiatric Disease and Treatment 8, pages 245-246.
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Articles from other publishers (7)

Uzma Zahid, Robert A. McCutcheon, Faith Borgan, Sameer Jauhar, Fiona Pepper, Matthew M. Nour, Maria Rogdaki, Martin Osugo, Graham K. Murray, Pamela Hathway, Robin M. Murray & Oliver D. Howes. (2022) The effect of antipsychotics on glutamate levels in the anterior cingulate cortex and clinical response: A 1H-MRS study in first-episode psychosis patients. Frontiers in Psychiatry 13.
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Pallab Bhattacharyya, Amit Anand, Jian Lin & Murat Altinay. (2021) Left Dorsolateral Prefrontal Cortex Glx/tCr Predicts Efficacy of High Frequency 4- to 6-Week rTMS Treatment and Is Associated With Symptom Improvement in Adults With Major Depressive Disorder: Findings From a Pilot Study. Frontiers in Psychiatry 12.
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S. Andrea Wijtenburg, Jeffrey West, Stephanie A. Korenic, Franchesca Kuhney, Frank E. Gaston, Hongji Chen & Laura M. Rowland. (2021) Multimodal Neuroimaging Study of Visual Plasticity in Schizophrenia. Frontiers in Psychiatry 12.
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Johanna Balz, Yadira Roa Romero, Julian Keil, Florian Schubert, Bernd Ittermann, Ralf Mekle, Christiane Montag, Jürgen Gallinat & Daniel Senkowski. (2018) Glutamate Concentration in the Superior Temporal Sulcus Relates to Neuroticism in Schizophrenia. Frontiers in Psychology 9.
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Alice Egerton, Akarmi Bhachu, Kate Merritt, Grant McQueen, Agata Szulc & Philip McGuire. (2017) Effects of Antipsychotic Administration on Brain Glutamate in Schizophrenia: A Systematic Review of Longitudinal 1H-MRS Studies. Frontiers in Psychiatry 8.
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Junjie Wang, Yingying Tang, Tianhong Zhang, Huiru Cui, Lihua Xu, Botao Zeng, Yu Li, Gaiying Li, Chunbo Li, Hui Liu, Zheng Lu, Jianye Zhang & Jijun Wang. (2016) Reduced γ -Aminobutyric Acid and Glutamate+Glutamine Levels in Drug-Naïve Patients with First-Episode Schizophrenia but Not in Those at Ultrahigh Risk . Neural Plasticity 2016, pages 1-9.
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Oliver Gruber, Antonella Chadha Santuccione & Helmut Aach. (2014) Magnetic Resonance Imaging in Studying Schizophrenia, Negative Symptoms, and the Glutamate System. Frontiers in Psychiatry 5.
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