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Neuropsychiatric Disease and Treatment Volume 10, 2014 - Issue

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Review

Gabapentin enacarbil for the treatment of moderate to severe primary restless legs syndrome (Willis-Ekbom disease): 600 or 1,200 mg dose?

Akito Kume1 KUME Clinic, Nagoya, Japan;2 Nagoya Clinical Neuropharmacology Laboratory, Nagoya, JapanCorrespondence[email protected]

Pages 249-262 | Published online: 03 Feb 2014

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Theresa Mallick-Searle, Brett Snodgrass & Jeannine M Brant. (2016) Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology. Journal of Multidisciplinary Healthcare 9, pages 447-454.
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Elena P. Calandre, Fernando Rico-Villademoros & Mahmoud Slim. (2016) Alpha2delta ligands, gabapentin, pregabalin and mirogabalin: a review of their clinical pharmacology and therapeutic use. Expert Review of Neurotherapeutics 16:11, pages 1263-1277.
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Articles from other publishers (8)

Peter Young & Anna Heidbreder. 2020. Diagnostik und Therapie neurologischer Erkrankungen. Diagnostik und Therapie neurologischer Erkrankungen 335 351 .

Ningyuan Zhang, Yunfei Li, Yinghua Lv, Ling Xu, Junchao Chen, Hongxia Liu, Lujin Li & Qingshan Zheng. (2019) Quantitative Comparison of the Efficacies of 5 First‐Line Drugs for Primary Restless Leg Syndrome. The Journal of Clinical Pharmacology.
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Michele A. Faulkner. (2018) Use of α2δ Ligands for Restless Legs Syndrome/Willis Ekbom Disease. CNS Drugs 32:2, pages 149-159.
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James C. Anderson, Megan L. Fritz, John-Michael Benson & Brian L. Tracy. (2017) Nerve Decompression and Restless Legs Syndrome: A Retrospective Analysis. Frontiers in Neurology 8.
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Daniel O. Lee, Mark J. Buchfuhrer, Diego Garcia-Borreguero, Alon Y. Avidan, Mansoor Ahmed, Ryan Hays, William G. Ondo, Mark J. Jaros, Richard Kim & Gwendoline Shang. (2016) Efficacy of gabapentin enacarbil in adult patients with severe primary restless legs syndrome. Sleep Medicine 19, pages 50-56.
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Claudia Trenkwalder, Juliane Winkelmann, Yuichi Inoue & Walter Paulus. (2015) Restless legs syndrome—current therapies and management of augmentation. Nature Reviews Neurology 11:8, pages 434-445.
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Subhashie Wijemanne & Joseph Jankovic. (2015) Restless legs syndrome: clinical presentation diagnosis and treatment. Sleep Medicine 16:6, pages 678-690.
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Vivien C. Abad & Christian Guilleminault. 2015. Sleep, Neuronal Plasticity and Brain Function. Sleep, Neuronal Plasticity and Brain Function 503 553 .

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