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Case Report

Hepatotoxicity induced by clozapine: a case report and review of literature

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Pages 1585-1587 | Published online: 26 Aug 2014

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Katrin Druschky, Sermin Toto, Stefan Bleich, Jessica Baumgärtner, Rolf R. Engel, Renate Grohmann, Hannah B. Maier, Alexandra Neyazi, Yannick J. Rudolph, Eckart Rüther, Harald Schwörer, Johanna Seifert, Susanne Stübner & Detlef Degner. (2021) Severe drug-induced liver injury in patients under treatment with antipsychotic drugs: Data from the AMSP study. The World Journal of Biological Psychiatry 22:5, pages 373-386.
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Amira M Ghoneim & Suzan M Mansour. (2020) The Effect of Liver and Kidney Disease on the Pharmacokinetics of Clozapine and Sildenafil: A Physiologically Based Pharmacokinetic Modeling. Drug Design, Development and Therapy 14, pages 1469-1479.
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Renato de Filippis, Pau Soldevila-Matías, Pasquale De Fazio, Daniel Guinart, Inmaculada Fuentes-Durá, Jose M. Rubio, John M. Kane & Georgios Schoretsanitis. (2020) Clozapine-related drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a systematic review. Expert Review of Clinical Pharmacology 13:8, pages 875-883.
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Articles from other publishers (8)

Suehyun Lee, Jeong Hoon Lee, Grace Juyun Kim, Jong-Yeup Kim, Hyunah Shin, Inseok Ko, Seon Choe & Ju Han Kim. (2022) A Data-Driven Reference Standard for Adverse Drug Reaction (RS-ADR) Signal Assessment: Development and Validation. Journal of Medical Internet Research 24:10, pages e35464.
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Evangelia Papatriantafyllou, Dimitris Efthymiou, Maria Markopoulou, Efthymia-Maria Sakellariou & Emilia Vassilopoulou. (2022) The Effects of Use of Long-Term Second-Generation Antipsychotics on Liver and Kidney Function: A Prospective Study. Diseases 10:3, pages 48.
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Evangelia Papatriantafyllou, Dimitris Efthymiou, Maria Markopoulou, Efthymia-Maria Sakellariou & Emilia Vassilopoulou. (2022) Effects of long-term second generation antipsychotics use in liver and kindey function. Public Health and Toxicology 2:Supplement 1.
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Nancy Monroy-Jaramillo, José Jaime Martínez-Magaña, Blanca Estela Pérez-Aldana, Alberto Ortega-Vázquez, Janitza Montalvo-Ortiz & Marisol López-López. (2022) The role of alcohol intake in the pharmacogenetics of treatment with clozapine. Pharmacogenomics 23:6, pages 371-392.
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O. D. Ostroumova, E. V. Shikh, N. V. Shikh, T. M. Ostroumova & Y. A. Isaakyan. (2022) Drug-induced liver injury with cholestasis in the neurologist and psychiatric practice. Neurology, Neuropsychiatry, Psychosomatics 14:1, pages 14-21.
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Nevena Todorović Vukotić, Jelena Đorđević, Snežana Pejić, Neda Đorđević & Snežana B. Pajović. (2021) Antidepressants- and antipsychotics-induced hepatotoxicity. Archives of Toxicology 95:3, pages 767-789.
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Timon Geib, Madhuranayaki Thulasingam, Jesper Z. Haeggström & Lekha Sleno. (2020) Investigation of Clozapine and Olanzapine Reactive Metabolite Formation and Protein Binding by Liquid Chromatography-Tandem Mass Spectrometry. Chemical Research in Toxicology 33:9, pages 2420-2431.
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O. L. Romanova, D. V. Sudukov, M. A. Golubev, M. L. Blagonravov, V. V. Goshkoev & A. A. Churilov. (2019) Pathologic Changes in the Liver During Acute Exposure to Clozapine and Its Combination with Ethanol (Experimental Study). General Reanimatology 15:2, pages 27-35.
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