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Review

Sleeping tongue: current perspectives of genioglossus control in healthy individuals and patients with obstructive sleep apnea

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Pages 169-179 | Published online: 15 Jun 2018

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David Stevens, Sarah Appleton, Andrew D Vincent, Yohannes Melaku, Sean Martin, Tiffany Gill, Catherine Hill, Andrew Vakulin, Robert Adams & Gary Wittert. (2020) Associations of OSA and Nocturnal Hypoxemia with Strength and Body Composition in Community Dwelling Middle Aged and Older Men. Nature and Science of Sleep 12, pages 959-968.
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Articles from other publishers (33)

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Adrien Mialland, Ihab Atallah & Agnès Bonvilain. (2023) Toward a robust swallowing detection for an implantable active artificial larynx: a survey. Medical & Biological Engineering & Computing 61:6, pages 1299-1327.
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Valérie Attali, Mathilde Weber, Isabelle Rivals, Thomas Similowski, Isabelle Arnulf & Peggy Gatignol. (2023) Moderate-to-severe obstructive sleep apnea syndrome is associated with altered tongue motion during wakefulness. European Archives of Oto-Rhino-Laryngology 280:5, pages 2551-2560.
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Michele L. Singer, Ethan S. Benevides, Sabhya Rana, Michael D. Sunshine, Robert C. Martinez, Brian E. Barral, Barry J. Byrne & David D. Fuller. (2023) Optogenetic activation of the tongue in spontaneously breathing mice. Respiratory Physiology & Neurobiology 309, pages 103998.
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Meng-Han Zhang, Xin-Xin Han, Yun Lu, Jia-Jia Deng, Wei-Hua Zhang, Jia-Qi Mao, Jing Mi, Wang-Hui Ding, Meng-Jie Wu, Li-Ming Yu & Yue-Hua Liu. (2023) Chronic intermittent hypoxia impaired collagen synthesis in mouse genioglossus via ROS accumulation: A transcriptomic analysis. Respiratory Physiology & Neurobiology 308, pages 103980.
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William Poncin, Nils Correvon, Jonathan Tam, Jean‐Christian Borel, Mathieu Berger, Giuseppe Liistro, Benny Mwenge, Raphael Heinzer & Olivier Contal. (2022) The effect of tongue elevation muscle training in patients with obstructive sleep apnea: A randomised controlled trial. Journal of Oral Rehabilitation 49:11, pages 1049-1059.
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Bruno Bordoni, Allan R Escher, Anastasia Toccafondi, Luca Mapelli & Paolo Banfi. (2022) Obstructive Sleep Apnea and Role of the Diaphragm. Cureus.
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Brandon Nokes, Christopher N. Schmickl, Rebbecca Brena, Nana Naa‐Oye Bosompra, Dillon Gilbertson, Scott A. Sands, Rakesh Bhattacharjee, Dwayne L. Mann, Robert L. Owens, Atul Malhotra & Jeremy E. Orr. (2022) The impact of daytime transoral neuromuscular stimulation on upper airway physiology – A mechanistic clinical investigation. Physiological Reports 10:12.
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Tülay Çevik Saldiran, İlke Kara, Seval Kutlutürk Yikilmaz & Mehmet Durgun. (2022) Influence of Body Posture and Apnea Severity on the Tone and Elasticity of Upper Airway Muscles in Awake Patients With Obstructive Sleep Apnea: A Cross-Sectional Study. Journal of Manipulative and Physiological Therapeutics 45:5, pages 365-377.
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Yukinori Kuwajima, Grace Kim, Yoshiki Ishida, Shikino Matsumoto, Kaho Ogawa, Reiko Shimpo, Joichi Shimpo, Hiroshi Nagasaki, Shigemi Nagai & Chia-Yu Chen. (2022) Tongue Pressure Declines Early on in Patients with Malocclusion. Applied Sciences 12:9, pages 4618.
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Xiaofeng Wu, Zhou Pan, Wei Liu, Shiqian Zha, Yan Song, Qingfeng Zhang & Ke Hu. (2022) The Discovery, Validation, and Function of Hypoxia-Related Gene Biomarkers for Obstructive Sleep Apnea. Frontiers in Medicine 9.
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L.M. de Azeredo, L.C. de Souza, B.L.S. Guimarães, F.P. Puga, N.S.C.S. Behrens & J.R. Lugon. (2022) Inspiratory muscle training as adjuvant therapy in obstructive sleep apnea: a randomized controlled trial. Brazilian Journal of Medical and Biological Research 55.
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Bing Jiang, Jeonghee Kim & Hangue Park. (2022) Palatal Electrotactile Display Outperforms Visual Display in Tongue Motor Learning. IEEE Transactions on Neural Systems and Rehabilitation Engineering 30, pages 529-539.
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Marissa C. Ciesla, Yasin B. Seven, Latoya L. Allen, Kristin N. Smith, Elisa J. Gonzalez-Rothi & Gordon S. Mitchell. (2022) Daily acute intermittent hypoxia enhances serotonergic innervation of hypoglossal motor nuclei in rats with and without cervical spinal injury. Experimental Neurology 347, pages 113903.
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Mateus Ramos Amorim, Raouf Amin & Vsevolod Y. Polotsky. (2021) Of Mice and Babies: PHOX2B and Obstructive Apneas in Congenital Central Hypoventilation Syndrome. American Journal of Respiratory and Critical Care Medicine 204:10, pages 1128-1130.
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Sophie G. Carter & Danny J. Eckert. (2021) Effects of hypnotics on obstructive sleep apnea endotypes and severity: Novel insights into pathophysiology and treatment. Sleep Medicine Reviews 58, pages 101492.
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Eung-Kwon Pae & Ronald M. Harper. (2021) Elevated Hyoid Bone Position in Response to Mandibular Advancing Appliance Predicts Effectiveness of the Appliance for Obstructive Sleep Apnea. Frontiers in Dental Medicine 2.
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Rui‐Bin Yu, Chih‐Chung Huang, Chun‐Hsiang Chang, Ya‐Hui Wang & Jeng‐Wen Chen. (2020) Prevalence and patterns of tongue deformation in obstructive sleep apnea: A whole‐night simultaneous ultrasonographic and polysomnographic study. Journal of Sleep Research 30:3.
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S. Erridge, O. Moussa, C. McIntyre, A. Hariri, N. Tolley, B. Kotecha & S. Purkayastha. (2021) Obstructive Sleep Apnea in Obese Patients: a UK Population Analysis. Obesity Surgery 31:5, pages 1986-1993.
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Melina P. da Silva, Karolyne S. Magalhães, Daniel P. de Souza & Davi J. A. Moraes. (2021) Chronic intermittent hypoxia increases excitability and synaptic excitation of protrudor and retractor hypoglossal motoneurones. The Journal of Physiology 599:6, pages 1917-1932.
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Patrick McKeown, Carlos O’Connor-Reina & Guillermo Plaza. (2021) Breathing Re-Education and Phenotypes of Sleep Apnea: A Review. Journal of Clinical Medicine 10:3, pages 471.
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Denise Fernandes Barbosa, Lilian Chrystiane Giannasi, Liege Maria Di Bisceglie Ferreira, Miguel Meira e Cruz, Marcelo Corrêa Alves & Fausto Berzin. (2020) A singular oral appliance to treat obstructive sleep apnea in CPAP non-adherent patients. Dental Press Journal of Orthodontics 25:5, pages 44-50.
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Cyrel Ontimare Manlises, Jeng‐Wen Chen & Chih‐Chung Huang. (2020) Dynamic tongue area measurements in ultrasound images for adults with obstructive sleep apnea. Journal of Sleep Research 29:4.
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Chun-Hsiang Chang, Chih-Chung Huang, Ya-Hui Wang, Fang-Ju Chou & Jeng-Wen Chen. (2020) Ultrasound Shear-Wave Elastography of the Tongue in Adults with Obstructive Sleep Apnea. Ultrasound in Medicine & Biology 46:7, pages 1658-1669.
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Olga Dergacheva, Thomaz Fleury-Curado, Vsevolod Y Polotsky, Matthew Kay, Vivek Jain & David Mendelowitz. (2020) GABA and glycine neurons from the ventral medullary region inhibit hypoglossal motoneurons. Sleep 43:6.
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Yingqian Zhou, Di Zhao, Guoping Yin, Jingjing Li, Xin Cao, Yuhuan Zhang & Jingying Ye. (2019) Analysis of the myoelectric characteristics of genioglossus in REM sleep and its improvement by CPAP treatment in OSA patients. Sleep and Breathing 24:2, pages 471-482.
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Brien Hsu, Chitra Priya Emperumal, Vincent X. Grbach, Mariela Padilla & Reyes Enciso. (2020) Effects of respiratory muscle therapy on obstructive sleep apnea: a systematic review and meta-analysis. Journal of Clinical Sleep Medicine 16:5, pages 785-801.
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Omid Bafkar, Juan Carlos Cajas, Hadrien Calmet, Guillaume Houzeaux, Gary Rosengarten, Daniel Lester, Vu Nguyen, Stefan Gulizia & Ivan Stuart Cole. (2020) Impact of sleeping position, gravitational force & effective tissue stiffness on obstructive sleep apnoea. Journal of Biomechanics 104, pages 109715.
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Christopher Setzke, Oleg Broytman, John A. Russell, Natalie Morel, Michelle Sonsalla, Dudley W. Lamming, Nadine P. Connor & Mihaela Teodorescu. (2020) Effects of inhaled fluticasone propionate on extrinsic tongue muscles in rats. Journal of Applied Physiology 128:3, pages 576-585.
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Warren R. Ruehland, Peter D. Rochford, Robert J. Pierce, John Trinder, Amy S. Jordan, Jennifer M. Cori & Fergal J. O’Donoghue. (2019) Genioglossus muscle responses to resistive loads in severe OSA patients and healthy control subjects. Journal of Applied Physiology 127:6, pages 1586-1598.
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Olga Mediano, Sofia Romero-Peralta, Pilar Resano, Irene Cano-Pumarega, Manuel Sánchez-de-la-Torre, María Castillo-García, Ana Belén Martínez-Sánchez, Ana Ortigado & Francisco García-Río. (2019) Obstructive Sleep Apnea: Emerging Treatments Targeting the Genioglossus Muscle. Journal of Clinical Medicine 8:10, pages 1754.
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Wen-Yu Hsu, Nan-Ying Chiu, Cheng-Chen Chang, Ting-Gang Chang & Hsien-Yuan Lane. (2019) The association between cigarette smoking and obstructive sleep apnea. Tobacco Induced Diseases 17:April.
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