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Review

Corneal stromal demarcation line after collagen cross-linking in corneal ectatic diseases: a review of the literature

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Pages 1803-1810 | Published online: 19 Sep 2016

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Cosimo Mazzotta, Manuela Agata Pulvirenti, Marco Zagari, Safaa Jihad & Ashraf Armia Balamoun. (2023) Crosslinking for progressive keratoconus: is there room for improvement?. Expert Review of Ophthalmology 18:2, pages 121-133.
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Tomoya Nishida, Takashi Kojima, Takahiro Kataoka, Naoki Isogai, Yoko Yoshida & Tomoaki Nakamura. (2022) Evaluation of the Relationship Between the Changes in the Corneal Biomechanical Properties and Changes in the Anterior Segment OCT Parameters Following Customized Corneal Cross-Linking. Clinical Ophthalmology 16, pages 1909-1923.
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Julio C Hernandez-Camarena, Enrique O Graue-Hernandez, Denise Loya-García, Raul E Ruiz-Lozano & Jorge E Valdez-García. (2019) Correlation between corneal stromal demarcation line depth and topographic outcomes after two pulsed-light-accelerated crosslinking protocols. Clinical Ophthalmology 13, pages 1665-1673.
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Articles from other publishers (32)

Kassandra Xanthopoulou, Georgia Milioti, Loay Daas, Cristian Munteanu, Berthold Seitz & Elias Flockerzi. (2022) Accelerated corneal crosslinking causes pseudoprogression in keratoconus within the first 6 weeks without affecting posterior corneal curvature. European Journal of Ophthalmology 32:5, pages 2565-2576.
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Sofie Näslund, Jeannette Beckman Rehnman, Anneli Fredriksson & Anders Behndig. (2021) Comparison of two annular photorefractive intrastromal cross‐linking protocols in high oxygen for low‐grade myopia through 24‐month follow‐up. Acta Ophthalmologica 100:5, pages 549-558.
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Shyon Parsa, Alejandro Rodriguez, Danielle M. Robertson, Robert Wayne Bowman & Walter Matthew Petroll. (2022) Temporal and Spatial Assessment of the Corneal Response to UV Cross-Linking Using 3-Dimensional In Vivo Confocal Microscopy. Eye & Contact Lens: Science & Clinical Practice 48:7, pages 308-312.
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Tuna Celik Buyuktepe & Omur O. Ucakhan. (2021) Long-term visual, refractive, tomographic and aberrometric outcomes of corneal collagen crosslinking (CXL) with or without hypoosmolar riboflavin solution in the treatment of progressive keratoconus patients with thin corneas. Graefe's Archive for Clinical and Experimental Ophthalmology 260:4, pages 1225-1235.
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Sebastiano Serrao, Giuseppe Lombardo & Marco Lombardo. (2021) Adverse events after riboflavin/UV-A corneal cross-linking: a literature review. International Ophthalmology 42:1, pages 337-348.
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Fernando B. Cresta, Rosangela Simoncelli & Micheline B. Lucas. 2022. Keratoconus. Keratoconus 393 401 .
Sheetal Brar, C. R. Roopashree & Sri Ganesh. (2021) Incidence of Ectasia After SMILE From a High-Volume Refractive Surgery Center in India. Journal of Refractive Surgery 37:12, pages 800-808.
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Shira Hed, Ran Matlov Kormas, Sagi Shashar, Boris E. Malyugin, Matthew Boyko & Boris Knyazer. (2021) Corneal Cross-Linking as Treatment in Pediatric Keratoconus: Comparison of Two Protocols. Journal of Ophthalmology 2021, pages 1-7.
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Fanka Gilevska, Alma Biscevic, Smiljka Popovic Suic, Maja Bohac & Sudi Patel. (2021) Are changes in visual acuity and astigmatism after corneal cross-linking (CXL) in keratoconus predictable?. Graefe's Archive for Clinical and Experimental Ophthalmology 259:8, pages 2259-2268.
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Sri Ganesh, Sheetal Brar & Rohan Bowry. (2021) Management of small-incision lenticule extraction ectasia using tissue addition and pocket crosslinking. Journal of Cataract and Refractive Surgery 47:3, pages 407-412.
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AmaniE Badawi. (2021) Corneal haze and densitometry in keratoconus after collagen cross-linking by three different protocols. Journal of Current Ophthalmology 33:4, pages 422.
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Sally Hayes, Siân R. Morgan & Keith M. Meek. (2021) Keratoconus: cross-linking the window of the eye. Therapeutic Advances in Rare Disease 2, pages 263300402110035.
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Laura Toro-Giraldo, Norma Morales Flores, Omar Santana-Cruz, Arturo Ramirez-Miranda, Alejandro Navas, Andrew Olivo-Payne, Alejandro Lichtinger, Aida Jimenez-Corona & Enrique O. Graue-Hernández. (2021) Cool Crosslinking: Riboflavin at 4°C for Pain Management After Crosslinking for Keratoconus Patients, A Randomized Clinical Trial. Cornea 40:1, pages 1-4.
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Cristina Ariadna Nicula, Dorin Nicula, Anca Maria Rednik & Adriana Elena Bulboacă. (2020) Comparative Results of “Epi-Off” Conventional versus “Epi-Off” Accelerated Cross-Linking Procedure at 5-year Follow-Up. Journal of Ophthalmology 2020, pages 1-13.
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Asli Ayvaz, Jurriaan Brekelmans, Tos Berendschot, Mor M. Dickman, Nienke Visser, Rudy M.M.A. Nuijts & Isabelle E.Y. Saelens. (2020) Five years outcomes after corneal cross-linking for keratoconus. Journal of EuCornea 6, pages 9-12.
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Pavel Stodulka, Zuzana Halasova, Martin Slovak, Martin Sramka, Karel Liska & Jaroslav Polisensky. (2020) Photorefractive intrastromal crosslinking for correction of hyperopia: 12-month results. Journal of Cataract and Refractive Surgery 46:3, pages 434-440.
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Jiaonan Ma, Yan Wang & Vishal Jhanji. (2019) Corneal refractive surgery combined with simultaneous corneal cross‐linking: Indications, protocols and clinical outcomes—A review. Clinical & Experimental Ophthalmology 48:1, pages 78-88.
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Gregor Wollensak & Eberhard Spörl. (2018) Biomechanical efficacy of corneal cross-linking using hypoosmolar riboflavin solution. European Journal of Ophthalmology 29:5, pages 474-481.
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C. Cagini, G. Di Lascio, M. Messina, F. Riccitelli & HS Dua. (2018) Correlation of central and peripheral keratometric parameters after corneal collagen cross-linking in keratoconus patients. International Ophthalmology 39:9, pages 2041-2048.
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Anca Pantalon, Martin Pfister, Valentin Aranha dos Santos, Sabina Sapeta, Angelika Unterhuber, Niklas Pircher, Gerald Schmidinger, Gerhard Garhöfer, Doreen Schmidl, Leopold Schmetterer & René M. Werkmeister. (2019) Ultrahigh‐resolution anterior segment optical coherence tomography for analysis of corneal microarchitecture during wound healing. Acta Ophthalmologica 97:5.
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Mohammed Iqbal, Ahmed Elmassry, Ahmed Tawfik, Mervat Elgharieb, Khaled Nagy, Ashraf Soliman, Hisham Saad, Tarek Tawfik, Osama Ali, Ahmed Gad, Islam El Saman, Alaa Radwan, Hosam Elzembely, Amin Abou Ali & Omar Fawzy. (2018) Standard cross‐linking versus photorefractive keratectomy combined with accelerated cross‐linking for keratoconus management: a comparative study. Acta Ophthalmologica 97:4, pages e623-e631.
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Andreas Thorsrud, Anne Marie Hagem, Gunhild Falleth Sandvik & Liv Drolsum. (2018) Superior outcome of corneal collagen cross‐linking using riboflavin with methylcellulose than riboflavin with dextran as the main supplement. Acta Ophthalmologica 97:4, pages 415-421.
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Roy S. Rubinfeld, Ciro Caruso & Carmine Ostacolo. (2019) Corneal Cross-Linking: The Science Beyond the Myths and Misconceptions. Cornea 38:6, pages 780-790.
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Cristina Nicula, Radu Pop, Anca Rednik & Dorin Nicula. (2019) 10-Year Results of Standard Cross-Linking in Patients with Progressive Keratoconus in Romania. Journal of Ophthalmology 2019, pages 1-5.
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Riccardo Vinciguerra, Argyrios Tzamalis, Vito Romano, Esmaeil M. Arbabi, Mark Batterbury & Stephen B. Kaye. (2019) Assessment of the Association Between In Vivo Corneal Biomechanical Changes After Corneal Cross-linking and Depth of Demarcation Line. Journal of Refractive Surgery 35:3, pages 202-206.
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Leopoldo Spadea, Rita Napolitano, Emanuele Tonti & Vittoria De Rosa. 2019. Controversies in the Management of Keratoconus. Controversies in the Management of Keratoconus 75 81 .
Adel Barbara, Paul R. Meredith & Ramez Barbara. 2019. Controversies in the Management of Keratoconus. Controversies in the Management of Keratoconus 343 382 .
Jui-teng Lin. (2018) Influencing Factors Relating the Demarcation Line Depth and Efficacy of Corneal Crosslinking. Investigative Opthalmology & Visual Science 59:12, pages 5125.
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Michael W. Belin, Li Lim, Rajesh K. Rajpal, Farhad Hafezi, Jose A. P. Gomes & Beatrice Cochener. (2018) Corneal Cross-Linking: Current USA Status: Report From the Cornea Society. Cornea 37:10, pages 1218-1225.
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Louis Lhuillier, Cedric Ghetemme, Mathilde Boiché, Rekia Yahia, Naila Houmad, Mohamed Zaidi, Christophe Goetz & Jean Marc Perone. (2018) Visibility and Depth of the Stromal Demarcation Line After Corneal Collagen Cross-Linking Using Anterior Segment Optical Coherence Tomography: Comparison Between Isoosmolar and Hypoosmolar Riboflavin. Cornea 37:5, pages 567-573.
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Riccardo Vinciguerra, Vito Romano, Esmaeil M. Arbabi, Matthias Brunner, Colin E. Willoughby, Mark Batterbury & Stephen B. Kaye. (2017) In Vivo Early Corneal Biomechanical Changes After Corneal Cross-linking in Patients With Progressive Keratoconus. Journal of Refractive Surgery 33:12, pages 840-846.
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. (2017) Reflections on the Controversies on Collagen Corneal Cross-linking for Arresting Keratoconus. International Journal of Keratoconus and Ectatic Corneal Diseases 6:1, pages 0-0.
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