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Clinical Ophthalmology Volume 11, 2017 - Issue
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Clinical Trial Report

Pharmacokinetics and safety of olopatadine hydrochloride 0.77% in healthy subjects with asymptomatic eyes: data from 2 independent clinical studies

Edward Meier1 Apex Eye, Mason, OHCorrespondence[email protected]
,
Abhijit Narvekar2 Alcon Research Ltd., Fort Worth, TX
,
Ganesh R Iyer2 Alcon Research Ltd., Fort Worth, TX
,
Harvey B DuBiner3 Clayton Eye Center, Morrow, GA
,
Apinya Vutikullird4 WCCT Global, Cypress
,
David Wirta5 Eye Research Foundation, Newport Beach
&
Kenneth Sall6 Sall Eye Research Medical Center, Artesia, CA, USA
 show all
Pages 669-681 | Published online: 10 Apr 2017

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Piotr Kuna, Marek Jutel, Grazyna Pulka, Slawomir Tokarski, Paula Arranz, Gonzalo Hernández & Nieves Fernández Hernando. (2023) Safety and Tolerability of Bilastine 0.6% Ophthalmic Solution: An 8-Weeks Phase III Study. Clinical Ophthalmology 17, pages 735-746.
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Tianjing Ren, Xu Zhu, Natalie M. Jusko, Wojciech Krzyzanski & William J. Jusko. (2022) Pharmacodynamic model of slow reversible binding and its applications in pharmacokinetic/pharmacodynamic modeling: review and tutorial. Journal of Pharmacokinetics and Pharmacodynamics 49:5, pages 493-510.
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Jeewan S. Titiyal, Rajeswari Thangavel, Manpreet Kaur, Pradeep Venkatesh, T. Velpandian & Rajesh Sinha. (2021) Comparative evaluation of once-daily and twice-daily dosing of topical bromfenac 0.09%: aqueous pharmacokinetics and clinical efficacy study. Journal of Cataract and Refractive Surgery 47:9, pages 1115-1121.
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Umay Merve Güven & Ebru Başaran. (2021) In vitro-in vivo evaluation of olopatadine incorporated chitosan nanoparticles for the treatment of ocular allergy. Journal of Drug Delivery Science and Technology 64, pages 102518.
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Dolores Ochoa, Manuel Román, Carmen Belmonte, Samuel Martín-Vilchez, Gina Mejía-Abril, Francisco Abad-Santos, Gonzalo Hernández, Paula Arranz, Lorena Elgezabal & Nieves Fernández. (2021) Pharmacokinetics and Safety of a Bilastine Once-Daily, Preservative-Free, Ophthalmic Formulation. Advances in Therapy 38:7, pages 4070-4081.
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Cemal ÇavdarliPınar Topcu Yilmaz. (2020) Pupil Diameter, Corneal Thickness, and Anterior Chamber Alterations Following Topical Olopatadine Hydrochloride 0.1%: A Single-Masked Randomized Controlled Clinical Study. Journal of Ocular Pharmacology and Therapeutics 36:7, pages 540-544.
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Ketan M. Ranch, Furqan A. Maulvi, Mausam J. Naik, Akshay R. Koli, Rajesh K. Parikh & Dinesh O. Shah. (2019) Optimization of a novel in situ gel for sustained ocular drug delivery using Box-Behnken design: In vitro, ex vivo, in vivo and human studies. International Journal of Pharmaceutics 554, pages 264-275.
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Hakika Erdogan & Ozlem Cam. (2018) The Effect Of Topical Antihistamines Used Single Dose Daily in Allergic Conjunctivitis. The Open Ophthalmology Journal 12:1, pages 330-337.
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Samah Kandeel & Mohamed Balaha. (2018) Olopatadine enhances recovery of alkali-induced corneal injury in rats. Life Sciences 207, pages 499-507.
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