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Clinical Ophthalmology Volume 12, 2018 - Issue

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Review

Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review

Achini K MakuloluwaTennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UKCorrespondence[email protected]

Fatemeh ShamsTennent Institute of Ophthalmology, Gartnavel General Hospital, Glasgow, UK

Pages 227-236 | Published online: 24 Jan 2018

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A.L. Minella, M.I. Casanova, T.J. Chokshi, J. Kang, K. Cosert, M.M. Gragg, M.A. Bowman, M.E. Mccorkell, N.L. Daley, B.C. Leonard, C.J. Murphy, V.K. Raghunathan & S.M. Thomasy. (2023) The TGM2 inhibitor cysteamine hydrochloride does not impact corneal epithelial and stromal wound healing in vitro and in vivo. Experimental Eye Research 226, pages 109338.
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Mitchell Ross, Jonathan Mofford, Jennifer JingYuan Tian, Benjamin Muirhead, Emily Anne Hicks, Lindsay Sheardown & Heather Sheardown. (2023) Thermo-responsive and mucoadhesive gels for the treatment of cystinosis. Biomaterials Advances 144, pages 213235.
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Petroni Sergio, Iarossi Giancarlo, Federici Matteo, De Sanctis Carlo Maria, Petrocelli Gianni, Rosa Parrilla, Paola Valente & Buzzonetti Luca. (2022) Analysis of tear film in cystinosis patients treated with topical viscous cysteamine hydrochloride (Cystadrops ® ) . European Journal of Ophthalmology 32:6, pages 3358-3362.
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Ana Castro-Balado, Enrique Bandín-Vilar, Andrea Cuartero-Martínez, Laura García-Quintanilla, Gonzalo Hermelo-Vidal, Xurxo García-Otero, Lorena Rodríguez-Martínez, Jesús Mateos, Manuela Hernández-Blanco, Pablo Aguiar, Irene Zarra-Ferro, Miguel González-Barcia, Cristina Mondelo-García, Francisco J. Otero-Espinar & Anxo Fernández-Ferreiro. (2022) Cysteamine Eye Drops in Hyaluronic Acid Packaged in Innovative Single-Dose Systems: Stability and Ocular Biopermanence. Pharmaceutics 14:10, pages 2194.
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Jorge Jimenez, Jayde L. Resnick, Ahmad B. Chaudhry, Ilya Gertsman, Ken K. Nischal & Morgan V. DiLeo. (2022) Ocular biodistribution of cysteamine delivered by a sustained release microsphere/thermoresponsive gel eyedrop. International Journal of Pharmaceutics 624, pages 121992.
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Valeria Graceffa. (2022) Development of a fibrin-mediated gene delivery system for the treatment of cystinosis via design of experiment. Scientific Reports 12:1.
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Cristina Martín-Sabroso, Mario Alonso-González, Ana Fernández-Carballido, Juan Aparicio-Blanco, Damián Córdoba-Díaz, Federico Navarro-García, Manuel Córdoba-Díaz & Ana Torres-Suárez. (2021) Limitations and Challenges in the Stability of Cysteamine Eye Drop Compounded Formulations. Pharmaceuticals 15:1, pages 2.
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Zhen Liu, Uday B. Kompella & Anuj Chauhan. (2021) Gold nanoparticle synthesis in contact lenses for drug-less ocular cystinosis treatment. European Journal of Pharmaceutics and Biopharmaceutics 165, pages 271-278.
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Hong Liang, Antoine Labbé, Christophe Baudouin, Celine Plisson & Vincenzo Giordano. (2021) Long-term follow-up of cystinosis patients treated with 0.55% cysteamine hydrochloride. British Journal of Ophthalmology 105:5, pages 608-613.
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Sukhmandeep Kaur, Phulen Sarma, Hardeep Kaur, Manisha Prajapat, Nishant Shekhar, Jaimini Bhattacharyya, Harpinder Kaur, Subodh Kumar, Bikash Medhi, Jagat Ram, Dipankar Das, Pramod Avti, Ajay Prakash, Rahul Singh & Anusuya Bhattacharyya. (2021) Efficacy and Safety of Topical Cysteamine in Corneal Cystinosis: A Systematic Review and Meta-Analysis. American Journal of Ophthalmology 223, pages 275-285.
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Ana Castro-Balado, Cristina Mondelo-García, Iria Varela-Rey, Beatriz Moreda-Vizcaíno, Jesús F. Sierra-Sánchez, María Teresa Rodríguez-Ares, Gonzalo Hermelo-Vidal, Irene Zarra-Ferro, Miguel González-Barcia, Eva Yebra-Pimentel, María Jesús Giráldez-Fernández, Francisco J. Otero-Espinar & Anxo Fernández-Ferreiro. (2020) Recent Research in Ocular Cystinosis: Drug Delivery Systems, Cysteamine Detection Methods and Future Perspectives. Pharmaceutics 12:12, pages 1177.
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Anita Csorba, Erika Maka, Otto Alexander Maneschg, Attila Szabó, Nóra Szentmáry, Mária Csidey, Miklós Resch, László Imre, Krisztina Knézy & Zoltán Zsolt Nagy. (2020) Examination of corneal deposits in nephropathic cystinosis using in vivo confocal microscopy and anterior segment optical coherence tomography: an age-dependent cross sectional study. BMC Ophthalmology 20:1.
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Malgorzata Kowalczyk, Mario Damiano Toro, Robert Rejdak, Wojciech Załuska, Caterina Gagliano & Przemyslaw Sikora. (2020) Ophthalmic Evaluation of Diagnosed Cases of Eye Cystinosis: A Tertiary Care Center’s Experience. Diagnostics 10:11, pages 911.
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Filipe Sousa-Neves, Ana Clara Ribeiro, Eduardo Saraiva, Lígia Ribeiro, Joaquim Sequeira & Rosário Varandas. (2019) Ocular manifestations of intermediate cystinosis: To treat or not to treat?. European Journal of Ophthalmology 30:6, pages NP7-NP10.
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Johana Maria Guevara-Morales & Olga Yaneth Echeverri-Peña. (2020) Implementation of a method to quantify white blood cell cystine as a diagnostic support for cystinosis. Nefrología (English Edition) 40:1, pages 99-103.
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Johana Maria Guevara Morales & Olga Yaneth Echeverri Peña. (2020) Implementación de un método para la cuantificación de cistina intraleucocitaria como apoyo diagnóstico para la cistinosis. Nefrología 40:1, pages 99-103.
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Phillip Dixon, Kristin Powell & Anuj Chauhan. (2018) Novel approaches for improving stability of cysteamine formulations. International Journal of Pharmaceutics 549:1-2, pages 466-475.
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Andrea Minella, Marie Isabel Casanova, Tanvi Chokshi, Jennifer Kang, Krista Cosert, Megan Gragg, Morgan Bowman, Michelle Mccorkell, Nicole Daley, Brian Leonard, Christopher Murphy, VijayKrishna Raghunathan & Sara Thomasy. (2022) The TGM2 Inhibitor Cysteamine Hydrochloride Does Not Impact Corneal Epithelial and Stromal Wound Healing in Vitro and in Vivo. SSRN Electronic Journal.
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Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review

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Cysteamine hydrochloride eye drop solution for the treatment of corneal cystine crystal deposits in patients with cystinosis: an evidence-based review

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