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Review

Systane® lubricant eye drops in the management of ocular dryness

Umberto BenelliDepartment of Neurosciences, Section of Ophthalmology, University of Pisa, Pisa, ItalyCorrespondence[email protected]
Pages 783-790 | Published online: 10 Jun 2011

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Sruthi Srinivasan & Venkiteshwar Manoj. (2021) A Decade of Effective Dry Eye Disease Management with Systane Ultra (Polyethylene Glycol/Propylene Glycol with Hydroxypropyl Guar) Lubricant Eye Drops. Clinical Ophthalmology 15, pages 2421-2435.
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Renee Garofalo, Carolina Kunnen, Rekha Rangarajan, Venkiteshwar Manoj & Howard Ketelson. (2021) Relieving the symptoms of dry eye disease: update on lubricating eye drops containing hydroxypropyl-guar. Clinical and Experimental Optometry 104:8, pages 826-834.
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Silvia Tavazzi, Riccardo Origgi, Martina Anselmi, Andrea Corvino, Sara Colciago, Matteo Fagnola, Silvia Bracco & Fabrizio Zeri. (2020) Effects of Aqueous-Supplementing Artificial Tears in Wearers of Biweekly Replacement Contact Lenses vs Wearers of Daily Disposable Contact Lenses. Clinical Optometry 12, pages 75-84.
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Steven Silverstein, Elizabeth Yeu, Joseph Tauber, Michel Guillon, Lyndon Jones, David Galarreta, Sruthi Srinivasan & Venkiteshwar Manoj. (2020) Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clinical Ophthalmology 14, pages 3167-3177.
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Eleonora Favuzza, Michela Cennamo, Lidia Vicchio, Fabrizio Giansanti & Rita Mencucci. (2020) Protecting the Ocular Surface in Cataract Surgery: The Efficacy of the Perioperative Use of a Hydroxypropyl Guar and Hyaluronic Acid Ophthalmic Solution. Clinical Ophthalmology 14, pages 1769-1775.
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Gary Jerkins, Jack V Greiner, Louis Tong, Jacqueline Tan, Joseph Tauber, Ali Mearza & Sruthi Srinivasan. (2020) A Comparison of Efficacy and Safety of Two Lipid-Based Lubricant Eye Drops for the Management of Evaporative Dry Eye Disease. Clinical Ophthalmology 14, pages 1665-1673.
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Marc Labetoulle, Stefanie Schmickler, David Galarreta, Daniel Böhringer, Abayomi Ogundele, Michel Guillon & Christophe Baudouin. (2018) Efficacy and safety of dual-polymer hydroxypropyl guar- and hyaluronic acid-containing lubricant eyedrops for the management of dry-eye disease: a randomized double-masked clinical study. Clinical Ophthalmology 12, pages 2499-2508.
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Alejandro Aguilar, Martin Berra, Jorge Trédicce & Alejandro Berra. (2018) Efficacy of polyethylene glycol–propylene glycol-based lubricant eye drops in reducing squamous metaplasia in patients with dry eye disease. Clinical Ophthalmology 12, pages 1237-1243.
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Alison Ng, Adam Keech & Lyndon Jones. (2018) Tear osmolarity changes after use of hydroxypropyl-guar-based lubricating eye drops. Clinical Ophthalmology 12, pages 695-700.
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Maria Markoulli & Sailesh Kolanu. (2017) Contact lens wear and dry eyes: challenges and solutions. Clinical Optometry 9, pages 41-48.
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Nariman Nassiri, Yasaira Rodriguez Torres, Zachary Meyer, Michael A. Beyer, Gautham Vellaichamy, Amar S. Dhaliwal, Neil Chungfat & Frank S. Hwang. (2017) Current and emerging therapy of dry eye disease. Part A: pharmacological modalities. Expert Review of Ophthalmology 12:4, pages 269-297.
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Yuqiu Zhang, Hong Cao, Tong Lin & Lan Gong. (2016) Effects of artificial tears on rabbit ocular surface healing after exposure to benzalkonium chloride. Drug and Chemical Toxicology 39:4, pages 455-460.
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William G. Pitt, Yibei Zhao, Daniel R. Jack, Krystian X. Perez, Peter W. Jones, Ryan Marelli, Jared L. Nelson & John D. Pruitt. (2015) Extended elution of phospholipid from silicone hydrogel contact lenses. Journal of Biomaterials Science, Polymer Edition 26:4, pages 224-234.
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Seray Aslan Bayhan & Hasan Ali Bayhan. (2014) Lipid-containing osmoprotective eye drops in contact lens wearers. Clinical Ophthalmology 8, pages 2091-2093.
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Alejandro J Aguilar, Maria I Marquez, Paula A Albera, Jorge L Tredicce & Alejandro Berra. (2014) Effects of Systane® Balance on noninvasive tear film break-up time in patients with lipid-deficient dry eye. Clinical Ophthalmology 8, pages 2365-2372.
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Stephen Cohen, Anna Martin & Kenneth Sall. (2014) Evaluation of clinical outcomes in patients with dry eye disease using lubricant eye drops containing polyethylene glycol or carboxymethylcellulose. Clinical Ophthalmology 8, pages 157-164.
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Juan Francisco Llamas-Moreno, Leopoldo Martín Baiza-Durán, Laura Ray Saucedo-Rodríguez & José Félix Alaníz-De la O. (2013) Efficacy and safety of chondroitin sulfate/xanthan gum versus polyethylene glycol/propylene glycol/hydroxypropyl guar in patients with dry eye. Clinical Ophthalmology 7, pages 995-999.
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Christine W Sindt & Gary N Foulks. (2013) Efficacy of an artificial tear emulsion in patients with dry eye associated with meibomian gland dysfunction. Clinical Ophthalmology 7, pages 1713-1722.
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Michael Nye, Shara Rudner & Leonard Bielory. (2013) Emerging therapies in allergic conjunctivitis and dry eye syndrome. Expert Opinion on Pharmacotherapy 14:11, pages 1449-1465.
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Neha Gadaria-Rathod, Kyu-In Lee & Penny A Asbell. (2013) Emerging drugs for the treatment of dry eye disease. Expert Opinion on Emerging Drugs 18:2, pages 121-136.
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Holly Lorentz, Miriam Heynen, Helen Tran & Lyndon Jones. (2012) Using an In Vitro Model of Lipid Deposition to Assess the Efficiency of Hydrogen Peroxide Solutions to Remove Lipid from Various Contact Lens Materials. Current Eye Research 37:9, pages 777-786.
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