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Original Research

Ocular comfort assessment of lifitegrast ophthalmic solution 5.0% in OPUS-3, a Phase III randomized controlled trial

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Pages 263-270 | Published online: 31 Jan 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

David McMullin, David Clark, Bill Cavanagh, Paul Karpecki & Todd C Brady. (2021) A Post-Acute Ocular Tolerability Comparison of Topical Reproxalap 0.25% and Lifitegrast 5% in Patients with Dry Eye Disease. Clinical Ophthalmology 15, pages 3889-3900.
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Steven Silverstein, Elizabeth Yeu, Joseph Tauber, Michel Guillon, Lyndon Jones, David Galarreta, Sruthi Srinivasan & Venkiteshwar Manoj. (2020) Symptom Relief Following a Single Dose of Propylene Glycol-Hydroxypropyl Guar Nanoemulsion in Patients with Dry Eye Disease: A Phase IV, Multicenter Trial. Clinical Ophthalmology 14, pages 3167-3177.
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Agustin L Gonzalez. (2018) Safety and efficacy of lifitegrast 5% ophthalmic solution in contact lens discomfort. Clinical Ophthalmology 12, pages 2079-2085.
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Articles from other publishers (8)

John D. Sheppard, Leslie E. O'Dell, Paul M. Karpecki, Michael B. Raizman, Walter O. Whitley, Gretchen Blemker, Mandy Hemphill, Laura H. Hendrix, Andrea Gibson & Marian Macsai. (2023) Does Dry Eye Disease Severity Impact Efficacy of Varenicline Solution Nasal Spray on Sign and Symptom Treatment Outcomes?. Optometry and Vision Science 100:2, pages 164-169.
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Darrell E WhiteLaura H HendrixLucille SunIris TamMarian MacsaiAndrea A Gibson. (2023) Matching-adjusted indirect comparison of phase 3 clinical trial outcomes of OC-01 (varenicline solution) nasal spray and lifitegrast 5% ophthalmic solution for the treatment of dry eye disease. Journal of Managed Care & Specialty Pharmacy 29:1, pages 69-79.
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Hsiao-Hsuan Wang, Wei-Yu Chen, Yi-Hsun Huang, Sheng-Min Hsu, Yeou-Ping Tsao, Yu-Hsiang Hsu & Ming-Shi Chang. (2022) Interleukin-20 is involved in dry eye disease and is a potential therapeutic target. Journal of Biomedical Science 29:1.
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James Katz, Laura M. Periman, Sathi Maiti, Enrica Sarnicola, Mandy Hemphill, Alan G. Kabat, Laura H. Hendrix, Puja Shah & Andrea Gibson. (2022) Bilateral Effect of OC-01 (Varenicline Solution) Nasal Spray for Treatment of Signs and Symptoms in Individuals with Mild, Moderate, and Severe Dry Eye Disease. Clinical Therapeutics 44:11, pages 1463-1470.
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Bridgitte Shen Lee, Melissa Toyos, Paul Karpecki, Jessica Schiffbauer & John Sheppard. (2022) Selective Pharmacologic Therapies for Dry Eye Disease Treatment: Efficacy, Tolerability, and Safety Data Review from Preclinical Studies and Pivotal Trials. Ophthalmology and Therapy 11:4, pages 1333-1369.
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Dorota Kopacz & Piotr Maciejewicz. 2019. Chronic Autoimmune Epithelitis - Sjogren's Syndrome and Other Autoimmune Diseases of the Exocrine Glands. Chronic Autoimmune Epithelitis - Sjogren's Syndrome and Other Autoimmune Diseases of the Exocrine Glands.
Christopher E. Starr, Preeya K. Gupta, Marjan Farid, Kenneth A. Beckman, Clara C. Chan, Elizabeth Yeu, José A.P. Gomes, Brandon D. Ayers, John P. Berdahl, Edward J. Holland, Terry Kim & Francis S. Mah. (2019) An algorithm for the preoperative diagnosis and treatment of ocular surface disorders. Journal of Cataract and Refractive Surgery 45:5, pages 669-684.
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Stacy L. Haber, Vera Benson, Casey J. Buckway, Jennifer M. Gonzales, David Romanet & Brittany Scholes. (2019) Lifitegrast: a novel drug for patients with dry eye disease. Therapeutic Advances in Ophthalmology 11, pages 251584141987036.
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