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Review

Intracameral dexamethasone injection in the treatment of cataract surgery induced inflammation: design, development, and place in therapy

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Pages 2223-2235 | Published online: 01 Nov 2018

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Kamran Hosseini, Subba Gollamudi, Harvey Reiser, Tom Walters & Richard L Lindstrom. (2023) 0.2% Betamethasone Sodium Phosphate: A Multicenter, Randomized, Double-Masked Study to Compare Its Ocular Safety, Tolerability, and Efficacy to Vehicle in Cataract Surgery Subjects. Clinical Ophthalmology 17, pages 2219-2230.
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Fatma Sali, Veysel Aykut, Ahmad Kunbaz, Ebubekir Durmus, Mustafa Hepokur, Halit Oguz & Fehim Esen. (2023) Endothelial loss following postoperative intracameral triamcinolone acetonide and subconjunctival dexamethasone injections. Cutaneous and Ocular Toxicology 42:4, pages 237-242.
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Jason Bacharach, Cathleen McCabe, Mitchell Jackson, Sanjay Rao, I Paul Singh, Sebastian Heersink, Nathan Radcliffe, Robert Weinstock, Dario Paggiarino & Keyur Patel. (2022) First Real-World, Multicenter, Post-Marketing, Retrospective Study of Dexamethasone Intraocular Suspension for Inflammation After Cataract Surgery. Clinical Ophthalmology 16, pages 1783-1794.
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Articles from other publishers (35)

Anvesh Annadanam & Angela J. Verkade. (2023) Dropless Cataract Surgery. Advances in Ophthalmology and Optometry 8:1, pages 139-153.
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Liping Li, Fan Jia, Youxiang Wang, Jiamin Liu, Yi Tian, Xinghuai Sun, Yuan Lei & Jian Ji. (2023) Trans-corneal drug delivery strategies in the treatment of ocular diseases. Advanced Drug Delivery Reviews 198, pages 114868.
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Dandan Liu, Yipeng Zang, Ziwei Hu, Chenrui Yu, Zhenxing Han, Mengmeng Wang, Maodong Xu, Xiaofeng Zhao, Wenjin Yue & Guangjun Nie. (2023) Synthesis of silicone hydrogel for soft contact lens (SCLs) and sustainable release of dexamethasone. Reactive and Functional Polymers 186, pages 105532.
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Viliana Gugleva & Velichka Andonova. (2023) Recent Progress of Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as Ocular Drug Delivery Platforms. Pharmaceuticals 16:3, pages 474.
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Megha GautamRituka GuptaPriti SinghVidhya VermaSunil VermaParul MittalSamendra KarkhurAnanyan SampathRajiv R. Mohan & Bhavana Sharma. (2023) Intracameral Drug Delivery: A Review of Agents, Indications, and Outcomes. Journal of Ocular Pharmacology and Therapeutics 39:2, pages 102-116.
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Adaeze Linda Onugwu, Chinekwu Sherridan Nwagwu, Obinna Sabastine Onugwu, Adaeze Chidiebere Echezona, Chinazom Precious Agbo, Stella Amarachi Ihim, Prosper Emeh, Petra Obioma Nnamani, Anthony Amaechi Attama & Vitaliy V. Khutoryanskiy. (2023) Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases. Journal of Controlled Release 354, pages 465-488.
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Michael Korenfeld, Joe Gira, Kevin Jong, Joseph Martel, Steven Vold, Tom Walters, Dale Usner & Eric Donnenfeld. (2022) OCS-01 (Novel Topical Dexamethasone Formulation) in Inflammation and Pain Post Cataract Surgery: A Randomized, Double-Masked, Vehicle-Controlled Study. Clinical Therapeutics 44:12, pages 1577-1587.
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Tianyang Liu, Nkiruka Ibeanu, Steve Brocchini, Peng Tee Khaw, Yann Bouremel & Sahar Awwad. (2022) Development of an in vitro model to estimate mass transfer from the anterior cavity. Frontiers in Drug Delivery 2.
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Michelle Ai Ling Teo, Edward Bloch, Ramu Muniraju & Paul Ursell. (2022) Intraoperative subconjunctival steroid reduces the incidence of pseudophakic macular oedema: a cohort study of 20,066 consecutive phacoemulsification surgeries. Eye.
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Wissam Farhat, Vincent Yeung, Amy Ross, Francesca Kahale, Nikolay Boychev, Liangju Kuang, Lin Chen & Joseph B. Ciolino. (2022) Advances in biomaterials for the treatment of retinoblastoma. Biomaterials Science 10:19, pages 5391-5429.
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Sachin Nashik Sanap, Ashwini Kedar, Amol Chhatrapati Bisen, Sristi Agrawal & Rabi Sankar Bhatta. (2022) A recent update on therapeutic potential of vesicular system against fungal keratitis. Journal of Drug Delivery Science and Technology 75, pages 103721.
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Sara Aly Attia & J. Andrew MacKay. (2022) Protein and polypeptide mediated delivery to the eye. Advanced Drug Delivery Reviews 188, pages 114441.
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John A. Hovanesian & Eric D. Donnenfeld. (2022) Intracameral dexamethasone 9% vs prednisolone acetate 1% in controlling postoperative pain and inflammation in patients undergoing cataract surgery. Journal of Cataract and Refractive Surgery 48:8, pages 906-911.
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Robin K. Kuriakose, Soungmin Cho, Saman Nassiri & Frank S. Hwang. (2022) Comparative Outcomes of Standard Perioperative Eye Drops, Intravitreal Triamcinolone Acetonide-Moxifloxacin, and Intracameral Dexamethasone-Moxifloxacin-Ketorolac in Cataract Surgery. Journal of Ophthalmology 2022, pages 1-8.
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Zachary Bergman, Ryan Thompson, Alan Malouf & Ramya Swamy. (2022) Iris Atrophy After Administration of Intracameral Dexycu in Routine Cataract Surgery: A Case Series. Eye & Contact Lens: Science & Clinical Practice 48:4, pages 185-187.
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Alessandro Meduri, Loredana Bergandi, Giovanni William Oliverio, Miguel Rechichi, Giuseppe Acri, Pietro Perroni, Francesca Silvagno & Pasquale Aragona. (2021) The cold eye irrigation BSS solution used during phacoemulsification reduces post-surgery patients discomfort preventing the inflammation. European Journal of Ophthalmology 32:2, pages 911-917.
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Sophia G. Antimisiaris & Evangelos Natsaridis. 2022. Applications of Nanovesicular Drug Delivery. Applications of Nanovesicular Drug Delivery 53 80 .
Atul Arora, Nikita Gupta & Vishali Gupta. 2022. Diabetic Macular Edema. Diabetic Macular Edema 95 105 .
Gordon T. Brown, Peter A. Karth & Allan A. Hunter. (2021) Novel Postoperative Dropless Protocol for Micro-Incision Vitrectomy Surgery. Ophthalmic Surgery, Lasers and Imaging Retina 52:11, pages 587-591.
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Nadia Toffoletto, Madalena Salema-Oom, Soledad Anguiano Igea, Carmen Alvarez-Lorenzo, Benilde Saramago & Ana Paula Serro. (2021) Drug-Loaded Hydrogels for Intraocular Lenses with Prophylactic Action against Pseudophakic Cystoid Macular Edema. Pharmaceutics 13:7, pages 976.
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Tobias Sonntag, Franziska Froemel, W. Daniel Stamer, Andreas Ohlmann, Rudolf Fuchshofer & Miriam Breunig. (2021) Distribution of Gold Nanoparticles in the Anterior Chamber of the Eye after Intracameral Injection for Glaucoma Therapy. Pharmaceutics 13:6, pages 901.
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Blanca Lorenzo-Veiga, Carmen Alvarez-Lorenzo, Thorsteinn Loftsson & Hakon Hrafn Sigurdsson. (2021) Age-related ocular conditions: Current treatments and role of cyclodextrin-based nanotherapies. International Journal of Pharmaceutics 603, pages 120707.
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Sherif A. Gaballa, Uday B. Kompella, Omar Elgarhy, Ali M. Alqahtani, Barbara Pierscionek, Raid G. Alany & Hamdy Abdelkader. (2020) Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives. Drug Delivery and Translational Research 11:3, pages 866-893.
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Claudio Furino, Francesco Boscia, Alfredo Niro, Maria D'Addario, Maria O. Grassi, Valeria Saglimbene, Michele Reibaldi & Giovanni Alessio. (2021) DIABETIC MACULAR EDEMA AND CATARACT SURGERY. Retina 41:5, pages 1102-1109.
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Meg Ferrell Ramos, Jacqueline Brassard & Sharmila Masli. (2021) Immunology and Pathology in Ocular Drug Development. Toxicologic Pathology 49:3, pages 483-504.
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Cynthia Matossian, John Hovanesian, Jason Bacharach, Dario Paggiarino & Keyur Patel. (2021) Impact of dexamethasone intraocular suspension 9% on intraocular pressure after routine cataract surgery: post hoc analysis. Journal of Cataract and Refractive Surgery 47:1, pages 53-64.
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Kerry K. Assil, Michael D. Greenwood, Andrea Gibson, Srilatha Vantipalli, Jamie L. Metzinger & Michael H. Goldstein. (2021) Dropless cataract surgery: modernizing perioperative medical therapy to improve outcomes and patient satisfaction. Current Opinion in Ophthalmology 32:1, pages S1-S12.
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Nadia Toffoletto, Benilde Saramago & Ana Paula Serro. (2020) Therapeutic Ophthalmic Lenses: A Review. Pharmaceutics 13:1, pages 36.
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Fan Jia, Liping Li, Yu Fang, Maomao Song, Jiaping Man, Qiao Jin, Yuan Lei & Jian Ji. (2020) Macromolecular Platform with Super-Cation Enhanced Trans-Cornea Infiltration for Noninvasive Nitric Oxide Delivery in Ocular Therapy. ACS Nano 14:12, pages 16929-16938.
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Duc Dung Nguyen & Jui-Yang Lai. (2020) Advancing the stimuli response of polymer-based drug delivery systems for ocular disease treatment. Polymer Chemistry 11:44, pages 6988-7008.
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Sherif A. Gaballa, Omar H. El Garhy, Hossam Moharram & Hamdy Abdelkader. (2020) Preparation and Evaluation of Cubosomes/Cubosomal Gels for Ocular Delivery of Beclomethasone Dipropionate for Management of Uveitis. Pharmaceutical Research 37:10.
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Srividya Gorantla, Vamshi Krishna Rapalli, Tejashree Waghule, Prem Prakash Singh, Sunil Kumar Dubey, Ranendra N. SahaGautam Singhvi. (2020) Nanocarriers for ocular drug delivery: current status and translational opportunity. RSC Advances 10:46, pages 27835-27855.
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Arnold Lee & Hannah A. Blair. (2020) Dexamethasone Intracanalicular Insert: A Review in Treating Post-Surgical Ocular Pain and Inflammation. Drugs 80:11, pages 1101-1108.
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Li-Jyuan Luo, Duc Dung Nguyen & Jui-Yang Lai. (2020) Dually functional hollow ceria nanoparticle platform for intraocular drug delivery: A push beyond the limits of static and dynamic ocular barriers toward glaucoma therapy. Biomaterials 243, pages 119961.
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Ghobad Mohammadi, Shahla Mirzaeei, Shiva TaghePardis Mohammadi. (2019) Preparation and Evaluation of Eudragit® L100 Nanoparticles LoadedImpregnated with KT Tromethamine Loaded PVA -HEC Insertions forOphthalmic Drug Delivery. Advanced Pharmaceutical Bulletin 9:4, pages 593-600.
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