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Original Research

Augmenting trabeculectomy in glaucoma with subconjunctival mitomycin C versus subconjunctival 5-fluorouracil: a randomized clinical trial

Pages 491-494 | Published online: 18 Apr 2011

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Florentina Joyce Freiberg, Juliane Matlach, Franz Grehn, Sabine Karl & Thomas Klink. (2013) Postoperative subconjunctival bevacizumab injection as an adjunct to 5-fluorouracil in the management of scarring after trabeculectomy. Clinical Ophthalmology 7, pages 1211-1217.
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Mohammad-Reza Sedghipour, Ali Mostafaei & Yousef Taghavi. (2011) Low-dose subconjunctival bevacizumab to augment trabeculectomy for glaucoma. Clinical Ophthalmology 5, pages 797-800.
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Articles from other publishers (18)

Stefan Siewert, Sabine Kischkel, Andreas Brietzke, Ludmila Kinzel, Tobias Lindner, Ulf Hinze, Boris Chichkov, Wolfram Schmidt, Michael Stiehm, Niels Grabow, Rudolf F. Guthoff, Klaus-Peter Schmitz & Thomas Stahnke. (2023) Development of a Novel Valve-Controlled Drug-Elutable Microstent for Microinvasive Glaucoma Surgery: In Vitro and Preclinical In Vivo Studies. Translational Vision Science & Technology 12:3, pages 4.
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Lars Kuepfer, Georg Fuellen & Thomas Stahnke. (2023) Quantitative systems pharmacology of the eye: Tools and data for ocular QSP. CPT: Pharmacometrics & Systems Pharmacology 12:3, pages 288-299.
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Ved Prakash Gupta, Nitika Beri & Jolly Rohatgi. (2022) Comparative evaluation of outcomes of novel approach of subconjunctival Mitomycin C (MMC) injection at the end of trabeculectomy versus intraTenon injection of MMC prior to the initial conjunctival incision – A pilot study. Indian Journal of Ophthalmology 70:12, pages 4194-4200.
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Thomas Stahnke, Stefan Siewert, Thomas Reske, Wolfram Schmidt, Klaus-Peter Schmitz, Niels Grabow, Rudolf F. Guthoff & Andreas Wree. (2018) Development of a biodegradable antifibrotic local drug delivery system for glaucoma microstents. Bioscience Reports 38:4.
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Hamed Esfandiari, Mohammad Pakravan, Shahin Yazdani, Azadeh Doozandeh, Mehdi Yaseri & Ian P. Conner. (2018) Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up. Ophthalmology Glaucoma 1:1, pages 66-74.
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Kenzo J. Koike & Peter T. Chang. (2018) Trabeculectomy: A Brief History and Review of Current Trends. International Ophthalmology Clinics 58:3, pages 117-133.
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Stefan K. De Smedt, Yannick S. Fonteyne, Felicienne Muragijimana, Katie Palmer & Ian Murdoch. (2016) Glaucoma Surgery Outcome in Rwanda. Journal of Glaucoma 25:8, pages 698-703.
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Hatem A. Tawfik, Mohamed H. Abdulhafez, Yousef A. Fouad, Hazem O. Rashed & Wesam M. Osman. (2016) Revisiting the Role of the Myofibroblast in Socket Surgery: An Immunohistochemical Study. Ophthalmic Plastic & Reconstructive Surgery 32:4, pages 292-295.
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Xiaoyan Liu, Liang Du & Ni Li. (2016) The Effects of Bevacizumab in Augmenting Trabeculectomy for Glaucoma. Medicine 95:15, pages e3223.
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R A Mahdy, S M Al-Mosallamy, M A Al-Aswad, A Bor'i & W M El-Haig. (2015) Evaluation the adjunctive use of combined bevacizumab and mitomycinc to trabeculectomy in management of recurrent pediatric glaucoma. Eye 30:1, pages 53-58.
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Emily Cabourne, Jonathan CK Clarke, Patricio G Schlottmann & Jennifer R Evans. (2015) Mitomycin C versus 5-Fluorouracil for wound healing in glaucoma surgery. Cochrane Database of Systematic Reviews 2015:11.
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Yuka Aoyama, Hiroshi Murata & Makoto Aihara. (2015) Targeting a Low-Teen Intraocular Pressure by Trabeculectomy With a Fornix-Based Conjunctival Flap. Journal of Glaucoma 24:3, pages 225-232.
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Jeremy O'Connor, Ghee Soon Ang, Jennifer C Fan Gaskin, Dan Q Nguyen & Jonathan G Crowston. (2014) Wound Healing Modulation in Glaucoma Filtration Surgery–Conventional Practices and New Perspectives: The Role of Antifibrotic Agents (Part I). Journal of Current Glaucoma Practice 8:2, pages 37-45.
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A. Koutsonas, A. Remky & N. Plange. (2013) Langzeitergebnisse nach Trabekulektomie mit 5-FluorouracilLong-term results after trabeculectomy with 5-fluorouracil. Der Ophthalmologe 111:8, pages 749-756.
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Lígia I De Fendi, Gustavo V Arruda, Ingrid U Scott & Jayter S Paula. (2013) Mitomycin C  versus 5-fluorouracil as an adjunctive treatment for trabeculectomy: a meta-analysis of randomized clinical trials . Clinical & Experimental Ophthalmology 41:8, pages 798-806.
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Melissa H.Y. Wong, Rahat Husain, Bryan C.H. Ang, Gus Gazzard, Paul J. Foster, Hla M. Htoon, Tina T. Wong, Francis T. Oen, Peng T. Khaw, Steve K. Seah & Tin Aung. (2013) The Singapore 5-Fluorouracil Trial. Ophthalmology 120:6, pages 1127-1134.
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Kun Shi, Daode Wang, Xiaojian Cao & Yingbin Ge. (2013) Endoplasmic Reticulum Stress Signaling Is Involved in Mitomycin C(MMC)-Induced Apoptosis in Human Fibroblasts via PERK Pathway. PLoS ONE 8:3, pages e59330.
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Thomas Stahnke, Marian Löbler, Christian Kastner, Oliver Stachs, Andreas Wree, Katrin Sternberg, Klaus-Peter Schmitz & Rudolf Guthoff. (2012) Different fibroblast subpopulations of the eye: A therapeutic target to prevent postoperative fibrosis in glaucoma therapy. Experimental Eye Research 100, pages 88-97.
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