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Clinical Ophthalmology Volume 12, 2018 - Issue
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Expert Opinion

Initiation and maintenance of a Treat-and-Extend regimen for ranibizumab therapy in wet age-related macular degeneration: recommendations from the UK Retinal Outcomes Group

Winfried Amoaku1 Academic Ophthalmology, Division of Clinical Neuroscience, University of Nottingham, Nottingham, UK
,
Konstantinos Balaskas2 NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and University College of London Institute of Ophthalmology, London, UK;3 University of Manchester, Manchester, UK
,
Tomas Cudrnak4 Royal Eye Infirmary, University Hospitals Plymouth NHS Trust, Plymouth, UK
,
Louise Downey5 Hull and East Yorkshire Eye Hospital, Hull and East Yorkshire Hospitals NHS Trust, Hull, UK
,
Markus Groppe6 Ophthalmology, Stoke Mandeville, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK
,
Sajjad Mahmood7 Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK
,
Hemal Mehta8 Royal Free London NHS Foundation Trust, London, UK
,
Quresh Mohamed9 Gloucestershire Eye Unit, Cheltenham General Hospital, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK
,
Bushra Mushtaq10 Birmingham and Midland Eye Centre, Sandwell and West Birmingham NHS Trust, Birmingham, UK
,
Philip Severn11 South Tees Hospitals NHS Foundation Trust, Middlesbrough, UK
,
Athanasios Vardarinos12 Eye Treatment Centre, West Suffolk Hospital, West Suffolk NHS Foundation Trust, Bury St Edmunds, UK
,
Yit Yang13 Wolverhampton Eye Infirmary, The Royal Wolverhampton NHS Trust, Wolverhampton, UK, [email protected]Correspondence[email protected]
&
Saad Younis14 Ophthalmology, Western Eye Hospital, Imperial College Healthcare NHS Trust, London, UK
 show all
Pages 1731-1740 | Published online: 10 Sep 2018

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Gayatri Yadav, Raja Narayanan & Amithavikram R Hathibelagal. (2022) Chromatic and flicker threshold changes in age-related macular degeneration following anti-VEGF treatment. Clinical and Experimental Optometry 105:3, pages 313-319.
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Markus Groppe & Mandeep Singh Bindra. (2021) Restructuring Wet Age-Related Macular Degeneration Services During the COVID-19 Pandemic to Allow Social Distancing Outpatient Clinics (SDOC). Clinical Ophthalmology 15, pages 651-659.
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Ellie Bowditch, Eugenia Chu, Thomas Hong & Andrew A. Chang. (2021) Treat and extend paradigm in management of neovascular age-related macular degeneration: current practice and future directions. Expert Review of Ophthalmology 16:4, pages 267-286.
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Hemal Mehta, Leah N Kim, Thibaud Mathis, Pardis Zalmay, Faruque Ghanchi, Winfried M Amoaku & Laurent Kodjikian. (2020) Trends in Real-World Neovascular AMD Treatment Outcomes in the UK. Clinical Ophthalmology 14, pages 3331-3342.
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Winfried Amoaku, Clare Bailey, Louise Downey, Richard P Gale, Faruque Ghanchi, Robin Hamilton, Sajjad Mahmood, Geeta Menon, Jenny Nosek, Ian Pearce & Yit Yang. (2020) Providing a Safe and Effective Intravitreal Treatment Service: Strategies for Service Delivery. Clinical Ophthalmology 14, pages 1315-1328.
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Siqing Yu, René Rückert & Marion R. Munk. (2019) Treat-and-extend regimens with anti-vascular endothelial growth factor agents in age-related macular degeneration. Expert Review of Ophthalmology 14:6, pages 287-307.
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Articles from other publishers (11)

Prem A. H. Nichani, Marko M. Popovic, Arjan S. Dhoot, Ananya Pathak, Rajeev H. Muni & Peter J. Kertes. (2023) Treat-and-extend dosing of intravitreal anti-VEGF agents in neovascular age-related macular degeneration: a meta-analysis. Eye.
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Bo Jiang, Lin Gao, Su Dong, Qingxue Hou, Minghao Sun, Jingjie Zhang, Haotian Yu, Zhongyu Zhang & Dawei Sun. (2021) The Influence of COVID-19 on the Stability of Patients with Neovascular Age-Related Macular Degeneration with Different Treatment Regimens. Advances in Therapy 39:4, pages 1568-1581.
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Ana I. Oca, Álvaro Pérez-Sala, Ana Pariente, Rodrigo Ochoa, Sara Velilla, Rafael Peláez & Ignacio M. Larráyoz. (2021) Predictive Biomarkers of Age-Related Macular Degeneration Response to Anti-VEGF Treatment. Journal of Personalized Medicine 11:12, pages 1329.
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Paolo Corazza, Francesco Maria D’Alterio, Jamil Kabbani, Mostafa Mohamed Ragheb Alam, Stefano Mercuri, Harry Otway Orlans & Saad Younis. (2021) Long-term outcomes of intravitreal anti-VEGF therapies in patients affected by neovascular age-related macular degeneration: a real-life study. BMC Ophthalmology 21:1.
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Maulik Bhavsar, Nitin Maksane, Utkarsh Shah, Anand Madhavan, Priyanka Dhar & Manan Thaker. (2021) Trends and practices in the management of neovascular age-related macular degeneration (nAMD) amongst ophthalmologists across India: Findings of a cross-sectional survey. Indian Journal of Clinical and Experimental Ophthalmology 7:3, pages 515-522.
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Konstantinos Balaskas, Winfried M. Amoaku, Tomas Cudrnak, Louise M. Downey, Markus Groppe, Sajjad Mahmood, Hemal Mehta, Quresh Mohamed, Bushra Mushtaq, Philip Severn, Athanasios Vardarinos & Yit C. Yang. (2021) Importance of Anatomical Efficacy for Disease Control in Neovascular AMD: An Expert Opinion. Ophthalmology and Therapy 10:2, pages 231-243.
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Voraporn Chaikitmongkol, Min Sagong, Timothy Y.Y. Lai, Gavin S.W. Tan, Nor Fariza Ngah, Masahito Ohji, Paul Mitchell, Chang-Hao Yang, Paisan Ruamviboonsuk, Ian Wong, Taiji Sakamoto, Anand Rajendran, Youxin Chen, Dennis S.C. Lam, Chi-Chun Lai, Tien Yin Wong, Chui Ming Gemmy Cheung, Andrew Chang & Adrian Koh. (2021) Treat-and-Extend Regimens for the Management of Neovascular Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy: Consensus and Recommendations From the Asia-Pacific Vitreo-retina Society. Asia-Pacific Journal of Ophthalmology 10:6, pages 507-518.
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Kenichiro Mori, Keijiro Ishikawa, Iori Wada, Yuki Kubo, Yoshiyuki Kobayashi, Takahito Nakama, Masatoshi Haruta, Masato Akiyama, Shintaro Nakao, Shigeo Yoshida & Koh-Hei Sonoda. (2020) Changes in metamorphopsia after the treat-and-extend regimen of anti-VEGF therapy for macular edema associated with branch retinal vein occlusion. PLOS ONE 15:10, pages e0241343.
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Miklós D. Resch, Anikó Balogh, Gábor Gy Deák, Zoltán Z. Nagy & András Papp. (2020) Vascular density in age-related macular degeneration after one year of antiVEGF treatment with treat-and-extend and fixed regimens. PLOS ONE 15:2, pages e0229388.
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Aditya Kelkar, Caroll Webers, Rohit Shetty, Jai Kelkar, Nikhil Labhsetwar, Abhishek Pandit, Madhulika Malode & Sayali Tidke. (2020) Factors affecting compliance to intravitreal anti-vascular endothelial growth factor therapy in Indian patients with retinal vein occlusion, age-related macular degeneration, and diabetic macular edema. Indian Journal of Ophthalmology 68:10, pages 2143.
Crossref
A. García-Layana, J. García-Arumí, M. S. Figueroa, L. Arias Barquet, J. M. Ruíz-Moreno, L. Monclús-Arbona & The Spanish AMD Multicenter Group. (2019) Management of Wet Age-Related Macular Degeneration in Spain: Challenges for Treat and Extend Implementation in Routine Clinical Practice. Journal of Ophthalmology 2019, pages 1-10.
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